Gene Information

Name : serS (EFER_1042)
Accession : YP_002382206.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1073497 - 1074789 bp
Length : 1293 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTAATGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGTTGGGCGCTCTTGAGGAGCGTCGTAAAGTATTGCAGGTCAAAACGGAAAACCTGCAAGCGGAGCGTAACTCCC
GATCGAAATCCATTGGCCAGGCGAAAGCGCGGGGGGAAGATATCGAGCCTTTACGTCTGGAAGTGAACAAACTGGGCGAA
GAGCTGGATGCAGCAAAAGCCGAGCTGGATGCTTTACAGGCTGAAATTCGCGATATCGCGCTGACAATCCCTAACCTGCC
TGCAGATGAAGTGCCGGTAGGTAAAGATGAAAATGACAACGTTGAAGTCAGCCGCTGGGGTACCCCGCGTGAGTTTGACT
TCGAAGTTCGTGACCACGTGACGCTGGGTGAAATGCACTCTGGCCTGGACTTTGCAGCCGCAGTTAAGCTGACCGGTTCG
CGCTTTGTGGTGATGAAAGGGCAGATTGCTCGTATGCACCGCGCACTGGCGCAGTTTATGCTAGATCTGCATACCGAACA
GCACGGTTATAGTGAAAACTATGTTCCGTATCTGGTTAACCAGGACACGCTGTACGGTACAGGGCAGTTGCCGAAGTTTG
CTGGCGATCTGTTCCATACTCGTCCGCTGGAAGAAGAAGCAGATACCAGTAACTACGCACTGATCCCAACGGCAGAAGTT
CCGCTGACTAACCTGGTACGCGGTGAAATCATTGATGAAGATGATCTGCCAATTAAGATGACCGCCCACACCCCATGCTT
CCGTTCTGAAGCCGGTTCATATGGTCGTGACACCCGTGGTCTGATCCGTATGCACCAGTTCGACAAAGTTGAAATGGTGC
AGATCGTTCGCCCGGAAGACTCAATGGCGGCGCTGGAAGAGATGACCGGTCATGCGGAAAAAGTCCTGCAGTTGCTGGGC
CTGCCGTACCGTAAAATCATTCTTTGCACCGGCGACATGGGCTTTGGCGCTTGCAAAACTTACGACCTGGAAGTATGGAT
CCCGGCACAGAACACCTACCGCGAGATCTCTTCCTGCTCCAACGTTTGGGATTTCCAGGCGCGTCGTATGCAGGCACGTT
GCCGTAGCAAGTCGGACAAGAAAACCCGTCTGGTTCATACCCTGAACGGTTCTGGTCTGGCTGTTGGTCGTACGCTGGTT
GCGGTAATGGAAAACTATCAGCAGGCTGATGGTCGTATCGAAGTACCGGAAGTTTTACGCCCGTACATGAACGGCCTTGA
ATATATCGGTTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEV
PLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-102 57