Gene Information

Name : guaA (PCC7424_2880)
Accession : YP_002378153.1
Strain : Cyanothece sp. PCC 7424
Genome accession: NC_011729
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3204107 - 3205735 bp
Length : 1629 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCTACTCAAATACCATCAAAACCCAGCACTTCTGAGACTGTGCCGACAGAGTCTCTCAAAGAAAGAATTAACCGCCA
AATGATCGTTATTCTCGACTTTGGCTCTCAATACTCAGAATTAATTGCCCGTCGTATTCGGGAAACCAATGTTTACTCAG
AAGTTTTGTCTTATCGCACCAGTGCAGAACAACTGCGTCAACTTGCTCCCAAAGGGATTATCCTTTCAGGAGGCCCTAAC
TCAGTCTATGACAAAAATGCGCCCCAGTGTACCCAAGAAATTTGGGACTTAGGCATTCCTATTTTAGGAGTTTGCTATGG
GATGCAGTTGATGGTGCAACAGTTAGGCGGTAAAGTAGAACGAGCGAAACGGGCTGAATATGGCAAAGCCTCCCTACATA
TTGACGATCCTACCGATTTATTAACCAACGTAGAAGATAATTCTATTGCTTGGATGAGTCATGGCGACTCCTGTATAGAA
TTGCCAGACGGGTTTAAAATTCTCGCTCATACCGATAATACTCCCTGTGCAGCGATCGCCAATCACGAACAGAAATTATT
TGGGGTACAATTCCATCCGGAAGTGGTGCATTCAGTGGGCGGAATTGCACTCATTCGGAACTTTGTCTATCATATCTGTG
AATGTGAACCCACTTGGACAACAGAAGCCTTTGTAGAAGAAGCGATTAGAGAAATTAGGGCAAAAATTGGCGATAAACGG
GTCTTATTAGCCCTTTCCGGCGGGGTAGACTCTTCAACCCTAGCCTTTTTATTACATCGCGCCATTGGAGATCAATTAAC
CTGTATGTTTATCGATCAGGGGTTCATGCGAAAAGGAGAACCAGAACGCCTGATGGAAATTTTTGATCATCAGTTTCATA
TTCCTGTCGTTTATGTCAATAGTCGGGAGCAGTTCTTAGAGCAACTCAAAGGGGTAACTGATCCGGAAGAAAAACGCCGC
TTAATCGGTCATGAGTTTATCAAAGTTTTTGAAGAAGAATCAAATCGTCTTGGCCCCTTTGATTATTTAGCTCAAGGTAC
GCTTTATCCTGATGTGATCGAATCTGCCGATAGTAATGTCGATCCTCAAACCGGAGAACGAGTGGCGGTTAAAATTAAAA
GTCATCACAACGTCGGGGGACTGCCTAAAAATCTCCGCTTTAAATTGGTAGAACCTTTACGAAAACTCTTTAAAGATGAA
GTGAGAAAGGTGGCGCGATCGATTGGTTTACCAGAAGAAATTGTCCGTCGTCATCCCTTTCCGGGGCCTGGGTTAGCCAT
TCGCATTATTGGGGAAGTCACCTCCGAACGCTTGAAAATATTGCGGGATGCGGATTTTGTGGTACGGGATGAGATCTCTA
AGCAAGGAATGTATCACGATTTTTGGCAAGCGTTTGCGGTGTTGTTACCGGTGCGGAGTGTTGGAGTCATGGGAGATCAA
CGTACCTATGCTCACCCGGTTGTTTTACGATTAATCACCAGTGAAGATGGAATGACCGCAGATTGGGCCAAAGTTCCCTA
TGATTTATTAGAAATTATTTCTAATCGAATTGTTAACGAAGTTCGGGGAGTTAATCGGGTGGTTTATGATATTACTTCTA
AACCTCCTGGAACGATCGAATGGGAATAA

Protein sequence :
MATQIPSKPSTSETVPTESLKERINRQMIVILDFGSQYSELIARRIRETNVYSEVLSYRTSAEQLRQLAPKGIILSGGPN
SVYDKNAPQCTQEIWDLGIPILGVCYGMQLMVQQLGGKVERAKRAEYGKASLHIDDPTDLLTNVEDNSIAWMSHGDSCIE
LPDGFKILAHTDNTPCAAIANHEQKLFGVQFHPEVVHSVGGIALIRNFVYHICECEPTWTTEAFVEEAIREIRAKIGDKR
VLLALSGGVDSSTLAFLLHRAIGDQLTCMFIDQGFMRKGEPERLMEIFDHQFHIPVVYVNSREQFLEQLKGVTDPEEKRR
LIGHEFIKVFEEESNRLGPFDYLAQGTLYPDVIESADSNVDPQTGERVAVKIKSHHNVGGLPKNLRFKLVEPLRKLFKDE
VRKVARSIGLPEEIVRRHPFPGPGLAIRIIGEVTSERLKILRDADFVVRDEISKQGMYHDFWQAFAVLLPVRSVGVMGDQ
RTYAHPVVLRLITSEDGMTADWAKVPYDLLEIISNRIVNEVRGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-144 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-144 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-144 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-129 50