Gene Information

Name : leuS (BbuZS7_0257)
Accession : YP_002374774.1
Strain : Borrelia burgdorferi ZS7
Genome accession: NC_011728
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 255828 - 258350 bp
Length : 2523 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCTAAATACGAATTCATAAAAATTGAAAAAAAATGGCAAGAATTTTGGGATAATAACAAAACATACAAAGTAGAAGA
AGATCCAAGTATTCCCAAGGAAAAAAGATTGTATATACTTGACATGTTCCCCTATCCTTCTGCCAACGGGCTTCATGTTG
GTCATCCAGAAGGATACACAGCAACAGACATATTTGGAAGATACAAGCTTTTGAATGGATTTCATGTACTTCACCCGATA
GGATTTGATAGCTTTGGACTTCCTGCTGAAAATTACGCAATACAAACAGGAACTCACCCTCAAAAAAGTACAGAAGAAAA
TATTAATAAGTTTAAAAAACAAATAAAAGCTTTGGGGTTTGCCTATGATTGGGATCGAGAAATTAGAACACATGAGGAGA
ATTACTATAAATGGACACAGTGGATTTTCCTGCAATTATATAAAAAAGGGCTAGCTTATGTAAAAGAAATGCCTGTATGG
TACTGCCCCGAGCTTGGAACGGTACTAGCAAATGAAGAGATTATTCAAACTTCAGATGGACCAAAATCTGAGAGAGGATC
TTACAGCGTCGAAAAAAAATATTTAAGACAGTGGGTTTTAAAAATTACAAAGTATGCTGAAAGATTGCTAGACGACCTTG
AAGAATTAGAATGGCCTGAATCTGTAAAAGAAATGCAGCGAAATTGGATTGGCAAATCAACAGGAGTTGAAATTGAATTT
GAAATTGAAGGCCACAGCGATAAAATTAAAGTCTTTACAACAAGGCCAGACACAATCTTTGGCATCACATATTTAGTGAT
CGCACCAGAAAATAAACTAATAGAAAAAATAACAAAGAACAACTTTAAACAAAATGTTTTAAAATATGTAAAGCACGAAG
AACTCAAAAGCGATCTTAATAGGACTTCTCTTGAAAAAGATAAATCGGGAGTTTTCACAGGATCTTACGCATTTCATCCA
ATAACAAATGAAAAAATTCCAATTTGGGTTGGAAGCTACGTACTAGGAACTTACGGAACCGGAGCTGTAATGGGTGTTCC
AGCACATGATGAAAGAGACTTTCAATTTGCCAAAAAGTATCAATTAAAAATTTTACCCGTGATATCAAAATCGGGGAAAA
ATGAAATATTAGAAAAAGCATTTGTTGATGATGGAATTTCAATAAATTCTCCCAATGAATTTAATAATCTTAAAAATTCT
GAAGTAAAAGACAAAGTAATAAAATGGCTTACTAAAAACAAAAAAGGGAAAGAAAAAGTTGCCTACAAGCTTAGAGATTG
GATTTTTTCAAGACAAAGATACTGGGGAGAGCCTATACCCATTTTGTTTGATAAACTTGGAAATGCAATACCTTTAGAGG
AAAATGATCTTCCCTTAAAGCTTCCAGAAATTGCAAACTATAAACCTTCTGGAACAGGTGAATCTCCTTTGTCAAGAATT
AAAGATTGGGTAAACGTAAAAGATATGGGCTTTACAAGAGAAACAAACACAATGCCTCAATGGGCAGGCTCTTGTTGGTA
TTATTTAAGATACTTAGACCCCAAAAACTCAAAAGAGTTTGCAAACAAAAAAAAAATTGAATATTGGATGCCGGTTGATC
TATACATAGGCGGAGCTGAACATACAGTATTACACCTGCTTTACTCAAGGTTTTGGCACAAGGTTCTTTATGATCTAGGA
TACGTAAATACCAAAGAACCTTTTAAAAAGCTAATAAATCAAGGCATAATAACATCATTTTCTTATCAAAAAGAAAACGG
GGTTTTAATACCCAATGACCAAGTTATAGAAAAAGACAATAAATTTTTTGATAAAAAAGATAACAAAGAAGTAACCCAAG
TAATTGCCAAAATGTCAAAATCTTTAAAAAATGTAATAAACCCAGACGACATCATTAAGGAATTTGGAGCAGACTCAATG
AGAATTTATGAAATGTTTATGGGGCCACTAACAGATTCTAAGCCTTGGAACACTAAAGGAATTATTGGTGTTTTTCGATT
TTTAAACAAAATTTGGAACTTAAGAGAAAAAGAACTATCAAAAGAGAATCCCCCAAGGGAAATAATATCTGAACTACATA
AAGTAATAAAAAAAGTCACAGAAGACACAGAAAAACTAAATTTTAACACAGCAATCTCCGCCATGATGATATTTATAAAT
GAACTTCTAAAGTATGAAAAAAATTATTTAAACATATTTAAACCGTTTATCATTATTTTATCTCCCTATGCACCCCATTT
AGCAGAAGAGTTGTGGGAATATATTGGAGAGCTTCCTAGTTTATTCAAAAATTCAAAATGGCCAAAATTCGATGAAAGCC
TTATTATTAAAGACAAAAAAGAAATTGTCTTGCAAATAAATGGAAAAATAAAAGACAAAATTTTACTAAACAAAGAGACA
GGCGAAAAAGAACTAAAAGAAATAGCAATGGAAAATAGCAAAATAAAATCAAACTTATTAAATAAAAAAATAGTAAAAAT
AATTGTAATTAAAAACAAGCTTGTCAACATAGTGATAAAGTAA

Protein sequence :
MSKYEFIKIEKKWQEFWDNNKTYKVEEDPSIPKEKRLYILDMFPYPSANGLHVGHPEGYTATDIFGRYKLLNGFHVLHPI
GFDSFGLPAENYAIQTGTHPQKSTEENINKFKKQIKALGFAYDWDREIRTHEENYYKWTQWIFLQLYKKGLAYVKEMPVW
YCPELGTVLANEEIIQTSDGPKSERGSYSVEKKYLRQWVLKITKYAERLLDDLEELEWPESVKEMQRNWIGKSTGVEIEF
EIEGHSDKIKVFTTRPDTIFGITYLVIAPENKLIEKITKNNFKQNVLKYVKHEELKSDLNRTSLEKDKSGVFTGSYAFHP
ITNEKIPIWVGSYVLGTYGTGAVMGVPAHDERDFQFAKKYQLKILPVISKSGKNEILEKAFVDDGISINSPNEFNNLKNS
EVKDKVIKWLTKNKKGKEKVAYKLRDWIFSRQRYWGEPIPILFDKLGNAIPLEENDLPLKLPEIANYKPSGTGESPLSRI
KDWVNVKDMGFTRETNTMPQWAGSCWYYLRYLDPKNSKEFANKKKIEYWMPVDLYIGGAEHTVLHLLYSRFWHKVLYDLG
YVNTKEPFKKLINQGIITSFSYQKENGVLIPNDQVIEKDNKFFDKKDNKEVTQVIAKMSKSLKNVINPDDIIKEFGADSM
RIYEMFMGPLTDSKPWNTKGIIGVFRFLNKIWNLREKELSKENPPREIISELHKVIKKVTEDTEKLNFNTAISAMMIFIN
ELLKYEKNYLNIFKPFIIILSPYAPHLAEELWEYIGELPSLFKNSKWPKFDESLIIKDKKEIVLQINGKIKDKILLNKET
GEKELKEIAMENSKIKSNLLNKKIVKIIVIKNKLVNIVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 52