Gene Information

Name : lysS (PCC8801_0856)
Accession : YP_002371091.1
Strain : Cyanothece sp. PCC 8801
Genome accession: NC_011726
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 895910 - 897631 bp
Length : 1722 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTCCGAATCAACCCCCAAAAGAGCCTCATTCTGCTTCAAGTTTAGAAGAAATTCGCGCTACACGCTTAGAAAAAGT
TGAACAGTTGCAACAATTGGGATTAGTTCCCTACGCCTATAAATGGGAATCTACCCATACGGCAGCCAATTTACAAGATA
AATATGCCACTCTTAAAGATGGGGAAGAAGTTGATCTAGAAGTAGCGATCGCAGGAAGAATTATTGCCCGTCGTGTCTTC
GGAAAATTGGCCTTTTTTAGTCTTCAAGATGAAACCGGAACCATTCAATTATATTTAGATAAACAACAAATTGATACCTC
AATGACTGAGGTGACTGATGCCTTTAATACCCTGAAAAAATTAACCGATACAGGGGATATTTTAGGCGTTGTAGGAACCA
TTAAACGAACGGAAAAGGGAGAACTTTCGGTGAAGGTTCAAACCTATACGATTTTGACGAAATCTTTACTCCCTTTACCC
GATAAATGGCATGGGTTAACGGATACAGAAAAACGCTATCGTCAACGCTACGTCGATTTAATTGTTAATCCCCAAGTTCG
TCAAACTTTTCGCCGTCGGGCTCAAATTACCGCTTCTATTCGTCGTTATTTAGATGAGAACGGCTTTATCGAAATAGAAA
CTCCTGTTTTACAAAGTGAAGCGGGAGGAGCAGAAGCGCGTCCGTTTATTACCTATCATAACACCTTGGATATGGAATTA
TATCTGAGGATTGCTACCGAATTGCATCTAAAACGCTTAATTATTGGCGGCTTTGAAAAGGTGTTTGAATTGGGGCGAAT
TTTCCGTAATGAAGGAGTTTCTACTAAACATAATCCTGAGTTTACTTCCATCGAAGTTTATCAAGCCTACGCCGATTATT
TTGATATGATGGAGTTAACTGAAGCACTTATTACCAATGCCGCTCAAACCGTTTTAGGCACATTAAAACTTACCTATCAA
GAGACAGAAATTGATTTATCAACCCCTTGGCGACGGGTGACAATGACAGACATTGTTAAAGAAAAAACGGGGTTAGATTT
TGATAGCTTTACTGACTTTGAAAGTGCAAAAGAAGCAGCAAAAAAAGCAGGAATAGACGTTCCTGATGACTGTCCTTCTC
TCGGAAAATTAATGAATGAAGCCTTTGAACAAAAGGTAGAAGAAACCTTAATTCAACCGACTTTTATTCTAGATTTTCCC
GTAGAAATTTCACCCTTAGCAAAACCCCATCGCTCTAAAAAAGGGTTAGTAGAACGTTTTGAATTATACATTGTTGGCCG
AGAATTAGCCAATAGTTTTTCGGAATTAACCGATCCCATCGATCAACGGGAAAGATTAGAAAAACAAGCCGAACAAAAGG
CCGCTGGAGACTTAGAGGCACAAGGAGTTGATGAAGATTTTCTAACTGCTTTGGAATACGGAATGCCTCCGACTGGAGGG
TTAGGCATTGGCATCGATCGCTTAGTTATGTTATTAACTGATTCTCCAAGTATTCGGGATGTAATTGCCTTTCCTCTCTT
AAAAAGTCAGAGTGTTGCTGTTAAGTCGTTTGACTATGATGCTGACAAAAAAATTCTTAGGGTTGAATTTACCAATGGCA
GTATTTATCAATACCATGATGTGCCTAAATCTCTCTATCAAGCGTTAGAAAAAGCTCCCTCAAAAGGACAGTTTTTTAAT
GCTGAAATACGGGATAAATTTGGGTTTGATCGAGAAGTTTAA

Protein sequence :
MSPNQPPKEPHSASSLEEIRATRLEKVEQLQQLGLVPYAYKWESTHTAANLQDKYATLKDGEEVDLEVAIAGRIIARRVF
GKLAFFSLQDETGTIQLYLDKQQIDTSMTEVTDAFNTLKKLTDTGDILGVVGTIKRTEKGELSVKVQTYTILTKSLLPLP
DKWHGLTDTEKRYRQRYVDLIVNPQVRQTFRRRAQITASIRRYLDENGFIEIETPVLQSEAGGAEARPFITYHNTLDMEL
YLRIATELHLKRLIIGGFEKVFELGRIFRNEGVSTKHNPEFTSIEVYQAYADYFDMMELTEALITNAAQTVLGTLKLTYQ
ETEIDLSTPWRRVTMTDIVKEKTGLDFDSFTDFESAKEAAKKAGIDVPDDCPSLGKLMNEAFEQKVEETLIQPTFILDFP
VEISPLAKPHRSKKGLVERFELYIVGRELANSFSELTDPIDQRERLEKQAEQKAAGDLEAQGVDEDFLTALEYGMPPTGG
LGIGIDRLVMLLTDSPSIRDVIAFPLLKSQSVAVKSFDYDADKKILRVEFTNGSIYQYHDVPKSLYQALEKAPSKGQFFN
AEIRDKFGFDREV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-107 49
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 5e-85 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002371091.1 lysyl-tRNA synthetase VFG1668 Protein 3e-107 49