Gene Information

Name : BCB4264_A0475 (BCB4264_A0475)
Accession : YP_002365253.1
Strain : Bacillus cereus B4264
Genome accession: NC_011725
Putative virulence/resistance : Resistance
Product : heavy metal-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 459957 - 461882 bp
Length : 1926 bp
Strand : -
Note : identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525

DNA sequence :
ATGAACTCAGAAGTAAAAACGTTACACGCAAAAGAAACAATTTCTCATCCCTCTTTATGGGACACATTAAAAAAACATTA
TGAACTTGTATTTGCATTGGCATCTGGTATTTTTATTTTAGCTGGCTGGCTATTCACAAAGAACGATGCAATGAATGCAG
GTATTACTTGCTATATCCTTGCTTATATAGTTGGTGGATATGCAAAAGCGAAAGAAGGAATTGAAGATACGATTGAAGAA
AAAGAGCTAAATGTTGAAATGCTAATGCTCTTTGCAGCTATCGGTGCTGCAATTATTGGCTACTGGGCAGAAGGGGCTAT
TTTAATCTTCATCTTTGCGCTCAGCGGTGCTATGGAATCTTATACATTAAGTAAGAGCCAAAAAGAAATTTCCGCTCTTC
TTGACTTACAACCCGAAGAAGCATTACGCATTTCCAACGGAACAGAGGAACGTATTCCTGTTGGAGAGTTACAAATTAAC
GACATTATTTTAATTAAACCAGGTGAACGTGTTCCTGCTGACGGTACGATTCATAACGGTGAAACAAATATCGATGAAGC
AGCAATCACGGGAGAACCTATTCCAAATGAGAAAAGACATGGCGATGAAGTATTTGCAGGTACTGTAAATTTACGTGGTG
CTATCGAAGTTAAAATTACGAAGCCGAGCGATCAAACATTATTCCAAAAGATTATCCGTCTCGTACAAAGTGCACAAAGT
GAAAAATCACCATCACAACTATTCATCGAAAAGTTTGAAGGAACATACGTAAAAGGTGTACTACTCGTTGTTGCGCTTAT
GATGTTCGTTCCTCATTTCTTACTTGACTGGAGCTGGAATGAAACGTTTTATCGCGCTATGATCTTACTTGTAGTCGCAT
CTCCTTGTGCACTCGTTGCTGCCATTACACCAGCAACGTTATCTGCAATTTCTAACGGAGCAAGAAATGGAATTCTCTTT
AAAGGTGGCATACATTTAGAACGCCTCGCTTCAGTAAAAGCAATCGCCTTTGATAAAACAGGAACATTAACAGAAGGAAA
ACCTACCGTAACAGATATATATGTTCGAGAAAATATGACAGAAAAAGAAGTACTTTCTATTACAGCATCAATTGAAAGTC
ACTCTACACATCCTTTGGCTGCATCTATTGTTAAATATGCACAACATGCGTACGACATTACATTAAAAAAACCAGAAAAG
GTTGAAGATGTAACTGGTTTTGGGCTAAAAGGAATATTCGAAAACAACGCTTATAAAATAGGTAAAGCTGATTTTATCGG
TGAAGAAACAAAAACATTTCATAATGGTATTTCTGCCTCACTTGAAAAGGAAGGTAAAACTGTCGTTTATATTAGTGATG
AGGGAGGCATTCTTGGACTTATCGCTTTAAAAGATACGCTTCGCCAAGAAACAATAGCTGCTATTCGTGATTTACAAAGC
ATTGGTGTCGAAGCAATTATGATTACTGGAGATAATGAAGAAACGGCAAAAGCAATTGCCTCTGAAAGTAATATAAAGGA
ATATTACGCATCATGCTTACCAGAAACAAAAGTTGAAACGATTAAAAAGTTAAAAGAAAAATACGGTACAGTAGCAATGG
TCGGAGACGGTATAAATGATGCACCTGCACTAGCTACTGCTAGCATTGGTGTCGCAATGGGAGAAGGAACAGATGTAGCT
TTAGAAACTGCGGATGTTGTACTGATGAAGAACGAACTATCTCGTCTTTCTCAAGCAATCCGTCTATCAAAACGAATGAA
TCGTATTGTGAAGCAAAACGTAATCTTTTCGCTAGCCGTTATTGCCATGCTAATTTGTTCAAACTTCTTGCAATTTTTAG
CTCTTCCATTCGGTGTTATTGGCCATGAAGGAAGTACGATTCTTGTCATTTTGAATGGCTTACGATTATTAAAAGGAAGC
AAATAA

Protein sequence :
MNSEVKTLHAKETISHPSLWDTLKKHYELVFALASGIFILAGWLFTKNDAMNAGITCYILAYIVGGYAKAKEGIEDTIEE
KELNVEMLMLFAAIGAAIIGYWAEGAILIFIFALSGAMESYTLSKSQKEISALLDLQPEEALRISNGTEERIPVGELQIN
DIILIKPGERVPADGTIHNGETNIDEAAITGEPIPNEKRHGDEVFAGTVNLRGAIEVKITKPSDQTLFQKIIRLVQSAQS
EKSPSQLFIEKFEGTYVKGVLLVVALMMFVPHFLLDWSWNETFYRAMILLVVASPCALVAAITPATLSAISNGARNGILF
KGGIHLERLASVKAIAFDKTGTLTEGKPTVTDIYVRENMTEKEVLSITASIESHSTHPLAASIVKYAQHAYDITLKKPEK
VEDVTGFGLKGIFENNAYKIGKADFIGEETKTFHNGISASLEKEGKTVVYISDEGGILGLIALKDTLRQETIAAIRDLQS
IGVEAIMITGDNEETAKAIASESNIKEYYASCLPETKVETIKKLKEKYGTVAMVGDGINDAPALATASIGVAMGEGTDVA
LETADVVLMKNELSRLSQAIRLSKRMNRIVKQNVIFSLAVIAMLICSNFLQFLALPFGVIGHEGSTILVILNGLRLLKGS
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 2e-105 43
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 2e-105 43
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-95 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-95 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCB4264_A0475 YP_002365253.1 heavy metal-transporting ATPase BAC0092 Protein 4e-132 47