Gene Information

Name : bacE (BCB4264_A2335)
Accession : YP_002367052.1
Strain : Bacillus cereus B4264
Genome accession: NC_011725
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2234190 - 2235806 bp
Length : 1617 bp
Strand : +
Note : identified by match to protein family HMM PF00501; match to protein family HMM TIGR02275

DNA sequence : 
ATGCTAGTAGGTTATACAGAATGGCCAAAAGAATTTGCCGATCGTTACCGAGAAGAAGGATGTTGGCTTGGTGAAACATT
TGGAGGAGTGTTAAGAGAGCGGGCTGAGAAATATGGAGATCAAATCGCGGTTGTAAGTGGTAAGAAGCATATAACATATA
GTGAACTTAATAAAAAGGTAGATCGTTTAGCAGCAGGTTTACTGAATTTAGGAATAAAGAAAGAGGACAGAGTTGTAATC
CAGTTACCTAACATTATCGAGTTTTTCGAAATATGTTTTGCACTATTTCGAATTGGAGCGCTTCCTGTCTTTGCACTGCC
GTCACATCGAAGCAGTGAAATTAGTTATTTTTGTGATTTTGGCGAGGCGAGCGCTTACGTTATTTCAGATAAGGCTCTCG
GTTTTGATTATCGAAAACTAGCAAGAGAAGTGAAAGAGGAAGTGCCAAATTTACAACATGTAATTGTAGTGGGAGAAGAA
GAAGAGTTTGTGAACATAAATGATCTGTATATGGATCCCGTCTCATTACCAGAAGTTCAGCCAAGTGATGTTGCGTTTCT
CCAATTATCAGGAGGCACAACAGGTCTTTCTAAATTAATTCCTAGAACACATGATGACTATATTTATAGTTTACGTGTTA
GTGCTAAAATTTGTAATTTGAATGCAGAAAGCGTCTATATGGCAGTTCTTCCAGTAGCACACAATTACCCAATGAGTTCT
CCAGGGACATTTGGAACTTTCTATGCGGGTGGAAAAGTGGTATTGGCAACTGGTGGTAGTCCAGATGAGGCCTTTGCTCT
TATTGAAAAAGAAAAAGTTACAATTACAGCGCTCGTTCCGCCATTAGCAATGATTTGGCTTGATGCTGCATCTTCTCGTA
ATGCCGATTTATCGAGCTTAGAGGTTATTCAAGTAGGTGGTGCTAAGTTTAGCGCTGAGGTTGCAAGACGTATACGCCCT
ACATTTGGATGTACGTTACAGCAAGTATTCGGTATGGCGGAAGGATTAGTGAACTATACAAGATTAGAAGATCCGGAAGA
AATTATTATTCATACACAAGGTAGACCAATGTCTGCACTCGATGAAGTACGAGTTGTTGATGAAAATGACAACGATGTAC
AACCGGGCGAAGTAGGTAGTTTATTAACACGAGGTCCATATACAATTCGTGGTTACTATAAAGCCGAAGAGCATAATGCA
CGATCATTTACAAAGGATGGGTTTTATCGCACAGGTGATCTTGTAAAAGTAAATGAACAAGGATACATCATTGTAGAAGG
AAGAGATAAAGATCAAATTAACCGTGGTGGTGAGAAAGTTGCTGCGGAAGAAGTTGAAAATCATCTATTAGCACACGATG
CGATTCATGACGTAGCAATCGTATCTATGCCTGACGATTATTTAGGTGAACGCACCTGTGCTTTTGTTATAGTTCGCGGA
CAAGTTCCGGGAGTAAGTGAATTAAAAATGTTTTTAAGAGAACGTGGTATAGCGGCTTATAAAATTCCAGATCGAATTGA
ATTTATTGAATCATTCCCGCAAACAGGAGTCGGAAAAGTCAGCAAAAAAGAACTACGTAAAGTCATTGCTGAAAAACTTA
TTACAGTAAAACAATAA

Protein sequence : 
MLVGYTEWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVSGKKHITYSELNKKVDRLAAGLLNLGIKKEDRVVI
QLPNIIEFFEICFALFRIGALPVFALPSHRSSEISYFCDFGEASAYVISDKALGFDYRKLAREVKEEVPNLQHVIVVGEE
EEFVNINDLYMDPVSLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAKICNLNAESVYMAVLPVAHNYPMSS
PGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSRNADLSSLEVIQVGGAKFSAEVARRIRP
TFGCTLQQVFGMAEGLVNYTRLEDPEEIIIHTQGRPMSALDEVRVVDENDNDVQPGEVGSLLTRGPYTIRGYYKAEEHNA
RSFTKDGFYRTGDLVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAIHDVAIVSMPDDYLGERTCAFVIVRG
QVPGVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKELRKVIAEKLITVKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-117 49
ybtE CAA21394.1 - Virulence HPI Protein 1e-117 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-118 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-118 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-118 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-117 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-117 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-117 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-117 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bacE YP_002367052.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 8e-136 52
bacE YP_002367052.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-113 47
bacE YP_002367052.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 3e-111 45