Gene Information

Name : thyA (BCB4264_A2219)
Accession : YP_002366936.1
Strain : Bacillus cereus B4264
Genome accession: NC_011725
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 2122189 - 2123145 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAAAATGAATACTTAAATTTATGCCGCCATGTAATGGAACATGGTACGAAGAAAGAAGACCGTACAGG
GACAGGCACTGTATCTGTATTTGGATATCAAATGCGTTTTGATCTAAGTAAAGGTTTTCCTTTATTAACAACAAAGAGAG
TACCGTTTCGCCTTGTAGCAAGTGAACTGCTTTGGTTTATGAAAGGTGATACAAATATTCGCTATTTATTGCAGCATAAT
AATAACATTTGGAATGAATGGGCTTTTAAGAGCTGGGTAGAAAGTGATGAGTATACTGGTCCTGACATGACTGATTTTGG
TCTTCGCTCACAACAAGATGAAGAATTTAAAGTACAGTACGACGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ATGATGAGTTCTCAAATAAATATGGTTATTTAGGAGACGTTTACGGTAAACAGTGGCGTGCTTGGAAAACGACAGCTGGT
GAGACACTTGATCAATTAAAAGATGTAATTGAAATGATTAAAAAAACACCAGACTCACGTCGTTTAATCGTTTCTGCTTG
GAATCCAGAAGATGTACCAAGTATGGCCTTACCGCCTTGTCATACGTTATTCCAGTTTTATGTAGCAGATGGAAAGCTTT
CTTGTCAGTTATATCAAAGAAGTGGTGACATATTCCTTGGAATTCCATTTAACATTGCAAGTTACTCATTACTAACACAT
TTAATTGCACATGAATGCGGACTTGAAGTGGGAGAATTTGTTCATACAATTGGTGATGCACACATTTATACAAATCATTT
TGAACAAGTAGAAAAGCAATTGGCACGTGAACCACGTCCATTCCCGAAACTTACATTAAATCCAGATGTGAAATCTGTTT
TCGATTTTGAAATGGAAGATTTAACGATTGAAGGATACGATCCGCATCCAGCAATTAAAGCACCGGTTGCAGTATAA

Protein sequence :
MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKSWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDEFSNKYGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYSLLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNPDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 6e-106 65