Gene Information

Name : clpB (BCB4264_A1223)
Accession : YP_002365956.1
Strain : Bacillus cereus B4264
Genome accession: NC_011725
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1188467 - 1191067 bp
Length : 2601 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAAGAGCAAGATGGGTTAGCGGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTAAAGCAAGGTGCTGAAAGTTTAATTAAAAAGAAACCTTCTGTAACGGGGAGCGGTGCAGAA
GTTGGAAAATTGTATGTAACGAGCGCTCTGCAACAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATAAATCAATTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACGAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTAATCGGCCGTGA
TAGTGAAATACGACGTGTAATCCGTATTCTTTCACGTAAAACGAAAAACAATCCGGTTTTAATTGGGGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGCTAGCCCAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTGAAAGATAGAACGATT
TTTGCGTTAGATATGAGTGCACTCGTAGCTGGTGCGAAATTCCGTGGTGAGTTCGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGACGCATTTTATTATTCATTGATGAACTTCATACAATAGTTGGAGCTGGTAAAACAGAAG
GAGCCATGGATGCAGGAAATATGTTAAAACCGATGCTTGCACGTGGTGAACTGCATTGTATTGGAGCCACAACACTAGAT
GAATATCGCAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAGCCAACTGTTGA
AGATACGATTTCCATTTTACGTGGATTAAAAGAACGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGTGCGATTG
TAGCAGCATCTGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCAGATAAAGCAATTGATCTTGTTGACGAAGCG
TGTGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTGGAAAT
TGAAGAAGCGGCTCTTGGGAAAGAAACGGATCGTGGTAGCCAAGAGCGTCTAAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCCAGTGGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGACATTCACAAAGTTCGTGACTTACGTGAG
CATTTAGAACGTTTGCGTCGTGAATTAGAAGAAGCAGAAGGCAATTACGATTTAAATAAAGCAGCCGAACTTCGTCACGG
GAAAATTCCCGCAATTGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAAATTGCAGATATTGTTTCACGCTGGACTGGTATTCCTGTTGCGAAACTCGTGGAAGGT
GAACGCGAGAAATTATTACGCTTAGAGCAAATCTTATCAGAGCGTGTCATCGGACAAGAGGAAGCAGTAAGCTTAGTGTC
AGACGCGGTTCTTCGTGCTCGCGCTGGTATTAAAGATCCGAACCGCCCGATTGGTTCTTTCATCTTCTTAGGGCCAACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCCCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATTGACATG
TCTGAGTATATGGAAAAACACGCCGTGTCTCGCTTAATTGGTGCACCTCCTGGATATGTAGGATATGAAGAAGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCATATTCCGTTGTTTTATTAGATGAAATTGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGTCGTACAGTGGACTTTAAAAATACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTACTAGATGGATTAGAAGAAGATGGTTCGATTAAAGAGGAATCAAGAGA
CCTTGTAATGGGGCAATTAAGAGGACATTTCCGCCCTGAATTTTTAAACCGTGTGGATGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGCATTGTTGATAAAATTGTAAAAGAACTACAAGGTCGTCTAGCTGACCGTCACATTACA
GTAGAATTAACAGATGCAGCAAAAGAATTTGTTGTGGAAGCCGGTTTCGACCCAATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCACGAGAATTAATTGCAGGAACAATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAATAA

Protein sequence :
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQGAESLIKKKPSVTGSGAE
VGKLYVTSALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRDLVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002365956.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 2e-110 43