Gene Information

Name : BCB4264_A0102 (BCB4264_A0102)
Accession : YP_002364931.1
Strain : Bacillus cereus B4264
Genome accession: NC_011725
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 95312 - 97747 bp
Length : 2436 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGCATTGGGCATAA
TAACATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTAATTGCTCTTG
GATTGAGCCCGGAGAAAGTGCAAAAAGAGGTAGAAGCGTTAATTGGACGTGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCTCGTGCTAAAAAAGTTATTGAATTGTCTATGGATGAAGCGCGTAAGCTAGGACATTCTTACGTTGGAACAGAACA
TATTTTACTTGGCTTAATCCGTGAAGGTGAAGGTGTAGCGGCACGTGTATTAAATAATTTAGGTGTAAGCCTCAACAAAG
CAAGACAACAAGTGTTACAACTTCTTGGAAGTAACGAAGCAAGTTCAGGTCACCAAGGTGGTTCATCGACAAATGCAAAT
ACACCGACACTAGACAGTTTAGCGCGCGACTTAACAGTTGTTGCACGTGAGAATCGTTTGGATCCTGTTATTGGACGTAG
TAAAGAAATTCAACGTGTAATTGAAGTGTTAAGCCGTAGAACAAAAAACAATCCAGTGTTAATTGGAGAGCCTGGTGTAG
GTAAAACAGCAATTGCTGAAGGGTTAGCACAGCAAATCGTAAATAATGAAGTTCCTGAAACGTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGAACAGTGGTAGCTGGGACGAAATATCGTGGTGAGTTTGAAGATCGTTTAAAGAAAGTAATGGA
TGAAATACGTCAAGCAGGGAATATTATTCTATTTATTGATGAACTTCATACATTAATCGGTGCAGGTGGAGCAGAAGGTG
CAATCGATGCATCGAATATTTTAAAACCATCTTTAGCACGCGGAGAATTACAATGTATTGGTGCGACAACTTTAGATGAG
TATCGTAAATATATTGAAAAGGATGCAGCTTTAGAGAGACGTTTCCAGCCAATTCATGTTGATGAGCCGAGTCTAGAAGA
ATCAACTCAAATCTTGAAAGGGTTACGCGATCGTTATGAGGCGCATCACCGTGTGTCTATTACAGATGATGCAATTGATG
CAGCTGTAAAACTTTCAGATCGTTATATTACGGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTGCGTTCTTATACAACACCACCAAACTTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTCGAAAAGA
AAAAGATGCGGCTGTACAAAGTCAAGAGTTTGAAAAGGCTGCTTCCTTACGTGATATGGAACAACGCTTACGTGAGAAAT
TGGAAGATACAAAGCGTCAGTGGAAAGAACAACAAGGAAAAGAAAATTCAGAGGTTACGGTAGAAGATATTGCAAATGTC
GTTTCTACATGGACACGTATCCCTGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATTCT
TCATGATCGTGTCATCGGTCAGGATGAAGCTGTAGTGGCTGTAGCGAAAGCTGTTCGTCGTGCAAGAGCAGGATTGAAAG
ATCCGAAACGTCCAATTGGTTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACAGAATTAGCAAGAGCATTGGCA
GAATCTATGTTCGGTGATGAGGATGCAATGATTCGCATTGATATGTCTGAGTATATGGAGAAACATTCAACTTCTCGCTT
AGTTGGTTCTCCTCCAGGATATGTTGGGTATGAAGAAGGCGGACAATTAACAGAGAAGGTTCGTCGTAAGCCGTATTCAG
TTGTCCTATTAGATGAAGTAGAGAAGGCGCATCCCGATGTATTTAATATTTTACTACAGGTATTGGAAGATGGTCGTTTA
ACTGATTCTAAAGGACGTACAGTTGACTTCCGTAATACGATTGTTATTATGACGTCTAACGTTGGTGCTGAGGCGTTAAA
ACGTAACAAACATCTTGGATTTAACGTACAAGATGAAAGCCGTGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAGGCATTTCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTATTCCATATGCTTGAGAAAAAACATATT
CAAGAAATTGTGACTCTTATGGTAAATCAGTTAGTGAATCGCTTAAAAGAACAAGAAATTGAATTGCAATTAACAGAAGG
GGCGATTGCAGCTATTGCTGATAAAGGGTTTGATCGTGAATATGGTGCTCGTCCACTACGTAGAGCAATTCAGAAGCATG
TAGAAGATAGACTATCGGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGGCAAAAAGTTATCTTTGATGTAGAAGGGGAA
ACATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLEESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELQLTEGAIAAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
TFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCB4264_A0102 YP_002364931.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 78
BCB4264_A0102 YP_002364931.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 3e-148 52