Gene Information

Name : guaA (BbuZS7_B17)
Accession : YP_002364845.1
Strain :
Genome accession: NC_011724
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 15133 - 16668 bp
Length : 1536 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATACTCAGGCAATACTTGTATTAGATTTTGGATCCCAATATAGTCAACTAATTGCAAGAAGAATTAGAGAAATTGG
CGTTTATACAAAAGTAATACCTTACTATACTCCTTTAAAAGAAATTAAAAATATGAATATCTCAGGAATAATACTAGGTG
GAAGTCCTGCTTCTGTTTATTCAAAAGAAGCTCCTACCTTGGATATGGAAATTTTTAATTTGAAAATACCTGTTTTGGGA
ATATGCTATGGAATGCAAATAATTGTTAAATTATTTGGGGGCCTAGTATCTAAAGACTCTAAGCAAGAATATGGAAGCTC
TGAAATCTTTCTAAGAGATGAAAAATCTCTTTTATTTTCAGAACTTCCAAACAAATTTAAAATTATCATGAGTCATGGAG
ACAGTATTGAAAAAATTCCTGATAATTTCAAACAATTGGCTTTTACAAAAAATTGTATTGCTTCTATATCAAATGAAACT
CAAAAAATTTACGGCCTACAATTCCATCCAGAAGTAACTCATTCTGAATTTGGCGATCAAATACTTAAAAATTTTGTTTT
TAAAATTTGCCAAGCCCAAATTAATTGGTCATTAGAAGGCAATCTAGAAACCATTGTGAAAAAAATTAAGCTCAAAGTGG
GAAGCAAAAAGGTTATTTTAGGACTTTCTGGTGGCACAGACTCTTTAGTTTGCGCATTACTTATAAAAAAAGCTATAAAC
GAAAATTTGATCTGCGTTTTTGTAAACACTGGATTGTTGCGCAAAAATGAAGATAAAAAAATACTAGAATTAAAGCATCA
ATATGATTTAAATATAAAATTTATTGATGCTTCTATAAAATTCTTGAACCGTTTAAAAAACATAAGTGATCCTGAGGAAA
AGAGAAAAATAATAGGAAAAGAATTTGTAGATGTTTTTGAAAAAATTACTCTAGAAGATCAAAATATAGAATATTTAGCT
CAAGGAACAATTTATTCTGACGTAATTGAATCTAAATCAAAAGACAGCTCTTCTTCAAAAATCAAATCTCATCACAACGT
AGGGGGACTCCCAGATAAGATGAGTTTAAAACTCTTAGAACCTTTGAATGAATTTTTTAAAGATGAAATAATTCAAATCG
GAATAAATCTAGGTATTAAAAAAGAATCTCTTTACAGACATCCATTTCCCGGACCAGGACTAGCTATAAGAATAATTGGA
GAAGTAACACAAGAAAAGATAAATATCTTACAAGAAGCAGACAATATTCTAACAGAGGAGCTTTTTATAAATGATTTATA
TTATCAAATAAGACAAGCATTTGTTGTATTGCTTCCTGTCAAATCTGTAGGCGTAATGGGAGATCAAAGGACATATGAAT
ATACAGCTGTAATTAGATGTGTAAATACCCAAGACTTCATGACTGCAGAATGGACTGAACTTCCTTACAGTTTTTTAAAA
AAAGTTTCTTCAAGAATAATTAATGAAGTTCGGGGTATAAATAGAGTTTGTTATGATATATCTTCTAAGCCTCCATCAAC
CATAGAATGGGAATAA

Protein sequence :
MNTQAILVLDFGSQYSQLIARRIREIGVYTKVIPYYTPLKEIKNMNISGIILGGSPASVYSKEAPTLDMEIFNLKIPVLG
ICYGMQIIVKLFGGLVSKDSKQEYGSSEIFLRDEKSLLFSELPNKFKIIMSHGDSIEKIPDNFKQLAFTKNCIASISNET
QKIYGLQFHPEVTHSEFGDQILKNFVFKICQAQINWSLEGNLETIVKKIKLKVGSKKVILGLSGGTDSLVCALLIKKAIN
ENLICVFVNTGLLRKNEDKKILELKHQYDLNIKFIDASIKFLNRLKNISDPEEKRKIIGKEFVDVFEKITLEDQNIEYLA
QGTIYSDVIESKSKDSSSSKIKSHHNVGGLPDKMSLKLLEPLNEFFKDEIIQIGINLGIKKESLYRHPFPGPGLAIRIIG
EVTQEKINILQEADNILTEELFINDLYYQIRQAFVVLLPVKSVGVMGDQRTYEYTAVIRCVNTQDFMTAEWTELPYSFLK
KVSSRIINEVRGINRVCYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-113 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-113 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-113 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-101 43