Gene Information

Name : Tmz1t_2390 (Tmz1t_2390)
Accession : YP_002364218.1
Strain :
Genome accession: NC_011667
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 51283 - 53685 bp
Length : 2403 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: rme:Rm

DNA sequence :
ATGAGCAAATGCAGTGTTGGTAGTTGCGGATGTTCCATCGTGTCGCAGTCGCCGGGTGATTCGTCCCCCGACGGCCCCAA
CGGGAAGCTATACGGCGTCGACAGCACGGACTGCCCCACCGATGCGGCGCTGGTCCGCAACAATCTTGAACCCCTCGACG
GCGTGACGGGACTCAACCTCACCGTGACCCGGCAAAGGTCGGACGTGAGCGATCGCCCCGACCCGCCGGTCGCGGCCGAC
GCCGCCGTGCCAGCCATCGGTGCGCCGGCACAGCGCATCGATAAGACCACTGCTGCCGTGCACACGACGCTCGCGATCGC
CGGGATGGACTGTCCGACCGAGGAGGCGTTGATCCGGAGCAAGCTCGCTGGCATGGCCGGAGTGGCGGCGCTCGATTTCA
ACCTCGTCCAGCGTCGGCTGAGCGTGACGCATCGTCCGGGAGCATTGGAAGCGGTCCTCGGCGCCCTGAAAGCCATCGGT
CTCGAAGCGAAGGTCGAATCGGCAGGCACGGAGAGCGCAGCGCCGCCGATCAAACCCGCGCCCAAGACCCACTGGTGGCC
GATGGCGCTGGCCGGAGTCACCGCGACGTTGGCCGAGGGGGTGTATTGGCTCAACGGCGGTGACCACTGGACCGTCCTGG
CTCTCGCGCTGGTGTCGATCTTCAGTGGCGGTCTGGCGACCTACAAGAAAGGCTGGATCGCGCTCAGGCATCGCAATCTC
AACATCAACGCACTCATGTCGATTGCCGTGACCGGCGCGATGCTCATCGGACACTGGCCGGAAGCGGCCATGGTGATGTT
CCTCTTCGCACTGGCCGAGGTGATCGAAGCGAAATCGCTCGATCGGGCGCGCAATGCGATTCGCGGTCTGCTGGAACTCG
CGCCAGACACCGCGACGGTGCGCCAGGGCGATGGAAGCTGGGTGGTCGTGCCGGCCAAAACGGTGCCGCTGGAGGCCATG
GTGCGCGTGCGCCCCGGTGAGCGCATCGCGCTCGATGGCGTGGTGATCAGCGGACGTTCGACGGTCAATCAGGCGCCCAT
CACCGGAGAGAGCCTGCCGGTGGACAAAGGCGAAGGCGATAGCGTGTTCGCGGGCACGATCAATGAAGCGGGATCGCTGG
AATATCGCGTGACAGCGGAGGCGAAGCATTCCACCCTGGCCCGCATCATCCACGCCGTCGAATCCGCCCAGGGCAGCCGC
GCGCCCACCCAGCGCTTCGTCGACCGGTTCGCCCGGATCTACACGCCCGTCGTGTTCGCCGTCGCGCTGCTGGTGGCCAT
CGTGCCACCGCTAGCTTTCGACGGCGCGTGGATGGACTGGATCTACAAGGCGCTGGTGCTGCTGGTGATTGCCTGTCCGT
GTGCCTTGGTGATCTCGACGCCGGTCACGATCGTCAGCGGTCTCGCCGCGGCCGCCCGCAAGGGCATTCTGGTGAAAGGT
GGCGTCTATCTCGAAGAGGGGCGCAAACTCGCCACGCTGGCCCTCGACAAGACCGGCACGATTACGCACGGCAAGCCCGC
CCAGACGGACTTTCTGGTACTGAGCGGCGACGCGAACCAGGCGCATATCCTGGCAGGCAGTCTCGCGGCGCGCTCGGATC
ATCCGGTCTCGCTGGCGATCGCCCGTACCGCGGTTGAAATCGGATGGGTGCTGCGCGAGGTGACCGATTTCGCCGCCATT
CCGGGCCGAGGCGCGCGTGGCAGCATTGATGGTCACGTCTATCAGCTCGGCAACCATCGACTGATCGAGGAAATCGGCCT
GTGCTCACCCGACATCGAAAAAGCGCTCGACACGCTCGAGCGCCAAGGCAAGACGGCCGTACTCTTGGCGAACCATGCAG
AGGTGCTGGCCATCTTCGCCGTCGCCGACACGCTGCGCGAGACGAGCCGTCAGGCGATTGCCGATCTGCATTCCCTGGGG
GTGAAGACGCTGATGCTCACCGGCGATAACACTCACACGGCCGAAGCGATTGCCCGCGCGGTGGGTATCGACGAGGCAAG
GGGCAATCTGCTGCCCGAAGACAAACTCAGCACCATCGAATCACTGCTGACGCACCGGAAGGGGGGCAAGGTCGGCATGG
TGGGAGACGGCATCAACGACGCACCCTCGCTGGCCCGCGCGGACATCGGTTTCGCGATGGGGGCGGCGGGCACGGACACC
GCGATCGAGACCGCGGACGTGGCGTTGATGGACGACGACCTGCGCAAGATCCCCGCCTTCGTGCGCCTGTCACAGGCCAC
ATCCGACGTGCTGATCCAGAACATCGTAGTGGCGCTCGGCATCAAGGCGGTGTTTCTGCTGCTCACCGTGAGCGGGCAGG
CCACGATGTGGATGGCGGTATTCGCGGACATGGGGGCGAGTTTGCTGGTCGTGGCAAATGGACTCCGCTTGTTGCGGAGA
TAA

Protein sequence :
MSKCSVGSCGCSIVSQSPGDSSPDGPNGKLYGVDSTDCPTDAALVRNNLEPLDGVTGLNLTVTRQRSDVSDRPDPPVAAD
AAVPAIGAPAQRIDKTTAAVHTTLAIAGMDCPTEEALIRSKLAGMAGVAALDFNLVQRRLSVTHRPGALEAVLGALKAIG
LEAKVESAGTESAAPPIKPAPKTHWWPMALAGVTATLAEGVYWLNGGDHWTVLALALVSIFSGGLATYKKGWIALRHRNL
NINALMSIAVTGAMLIGHWPEAAMVMFLFALAEVIEAKSLDRARNAIRGLLELAPDTATVRQGDGSWVVVPAKTVPLEAM
VRVRPGERIALDGVVISGRSTVNQAPITGESLPVDKGEGDSVFAGTINEAGSLEYRVTAEAKHSTLARIIHAVESAQGSR
APTQRFVDRFARIYTPVVFAVALLVAIVPPLAFDGAWMDWIYKALVLLVIACPCALVISTPVTIVSGLAAAARKGILVKG
GVYLEEGRKLATLALDKTGTITHGKPAQTDFLVLSGDANQAHILAGSLAARSDHPVSLAIARTAVEIGWVLREVTDFAAI
PGRGARGSIDGHVYQLGNHRLIEEIGLCSPDIEKALDTLERQGKTAVLLANHAEVLAIFAVADTLRETSRQAIADLHSLG
VKTLMLTGDNTHTAEAIARAVGIDEARGNLLPEDKLSTIESLLTHRKGGKVGMVGDGINDAPSLARADIGFAMGAAGTDT
AIETADVALMDDDLRKIPAFVRLSQATSDVLIQNIVVALGIKAVFLLLTVSGQATMWMAVFADMGASLLVVANGLRLLRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 70
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 5e-126 47
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-128 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-128 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmz1t_2390 YP_002364218.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 71