Gene Information

Name : Msil_0586 (Msil_0586)
Accession : YP_002360920.1
Strain : Methylocella silvestris BL2
Genome accession: NC_011666
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 635121 - 636506 bp
Length : 1386 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTACGATATCAAATGGATTCGCGACAATCCTGAGGTCTTCGATCAGGGGCGCAAGCGGCGCGGACTGGAGCCTCTCGC
CGCGCGCCTGCTTGAGCTTGACGACGCCCGTCGCGGCGCAATCGCGAAATTGCAGGTGGCGCAGGAGCGCCGCAACGCCG
CCTCCAAGGAAATCGGTCAGGCGATGGCCGCGAAGGATCAGGCGAAAGCCGACGCCCTCATGGCCGAAGTGTCCGCCTTG
AAGCGCGACCTACCCGAACTTGAGGCGGCCGAGCGCGCCGCCGCGGCTTTGCTGGACAAGGCCTTATCCGAAATTCCCAA
TCTGCCGCTTGAAGAGGTTCCCTTCGGCCGCGACGAAAACGACAATCGCGAGCATCACACGTTTGGTGAGAAGCCGCGCT
TTTCCTTCGACCCCGCCGAGCATTACGAGCTTGGCGAGACCTTGGGGCTGATGGATTTCGAGACGGCCGCAAAGCTGTCG
GGCGCGCGGTTTGTGGTCAACAAGGGCCCGCTGGCGCGGCTGGAGCGGGCGCTTGGCGCCTTCATGCTCGACCTGCACAC
GGGCGAGCACGGCTATACTGAGGTCAATCCACCGATTCTGGTCCGCGATGACGCGATGTTCGGCACGGCGCAGCTGCCGA
AGTTCGAAAATGACCAATTTTGGGCTCGTCCAGGGGCGCATCCTCTTTTGATCGATATGTTCGGTAGGGAAGAGGCTGAG
GAAATGAAGAAAAACAGGCTTTGGCTCATCCCCACCGCGGAAGTCCCACTCACCAATCTCGTTCGTGAATCGATTCTCGA
CGAAAAACAGCTGCCCCTCCGCTTTACCGCCTCAACGCCCTGTTTTCGCGCCGAGGCCGGCTCGGCCGGGCGCGATACGC
GCGGCATGATTCGCCAGCATCAGTTCACCAAGGTGGAACTCGTCTCAATCACGACGCCGGAACAGGCGCTGGCCGAACAT
GAGCGCATGCTCAGCTGCGCCGAAGAGGTGTTGAAGCGGCTGAAGCTGCCCTATCGCGTCGTCACGCTCTGCACCGGCGA
CATGGGCTTCGCCTCGCAAAAAACCTATGACATCGAGGTTTGGCTGCCGGGACAGGACCGCTACCGCGAAATCTCCTCCG
TCTCGGTCTGCGGCGACTTTCAGGCGCGGCGGATGAACGCGCGCTATCGTCCCGAAGGAGCCAAGAACACGCGTTTCGTC
CATACGCTGAATGGTTCGGGCGTCGCCGTCGGACGCGCGCTGGTGGCTGTTCTTGAGAATTACCAGACGGAGGACGGCTC
TATTATTGTCCCGGACGCGCTGGCTCCCTATATGGGCGGGATCACCCGCATCGAAAAACCTGCGCTCGAAAGACCAAACT
CGGAAAAACCGGTCTCGCGCGCATGA

Protein sequence :
MYDIKWIRDNPEVFDQGRKRRGLEPLAARLLELDDARRGAIAKLQVAQERRNAASKEIGQAMAAKDQAKADALMAEVSAL
KRDLPELEAAERAAAALLDKALSEIPNLPLEEVPFGRDENDNREHHTFGEKPRFSFDPAEHYELGETLGLMDFETAAKLS
GARFVVNKGPLARLERALGAFMLDLHTGEHGYTEVNPPILVRDDAMFGTAQLPKFENDQFWARPGAHPLLIDMFGREEAE
EMKKNRLWLIPTAEVPLTNLVRESILDEKQLPLRFTASTPCFRAEAGSAGRDTRGMIRQHQFTKVELVSITTPEQALAEH
ERMLSCAEEVLKRLKLPYRVVTLCTGDMGFASQKTYDIEVWLPGQDRYREISSVSVCGDFQARRMNARYRPEGAKNTRFV
HTLNGSGVAVGRALVAVLENYQTEDGSIIVPDALAPYMGGITRIEKPALERPNSEKPVSRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-76 54