Gene Information

Name : Msil_0434 (Msil_0434)
Accession : YP_002360770.1
Strain : Methylocella silvestris BL2
Genome accession: NC_011666
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 476151 - 476861 bp
Length : 711 bp
Strand : +
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rpt:Rpal_2126 two component transcriptional regulator, winged helix family

DNA sequence : 
ATGCGCCTGCTCGTTGTCGAGGACGACAAGGATTTGAATCGGCAGATTGTTTCTGCGCTTGAGCGCGCGGGCTACGCCGT
CGATCGCGCCTTCGACGGCGAGGAGGGCTGGTTCCTCGGCGATACCGAGCCATATGACGGCGTCGTGCTCGATCTCGGCC
TGCCGGGCAAGGATGGCGTGACCGTCCTTTCCGATTGGCGCAAGGCCGGCCGCGTGATGCCGGTGTTGATCCTGACGGCG
CGCGACCGCTGGGGCGAAAAGGTCAAAGGGTTCGACGCTGGAGCCGATGATTATGTCACCAAGCCGTTTCATATCGAGGA
GCTGCTCGCCCGGCTGCGCGCCCTGATGCGGCGCTCCGCGGGCCATGCCTCGAGCGTGTTCTCCTGCGGTCCGGTCAGTT
TCGACGAACGCGGCGGCAAGGTTTCGGTCGAGGGACAGCCGGTCAAGCTCACCTCGCATGAATATCGGCTGCTGGGCTAT
TTGATGCATCATCAGGGCAAGATCGTTTCACGCGCCGAGATCGTGGAGCATCTCTACGATCAGGATTTCGACCGCGACTC
CAACACGATCGAGGTTTTTGTCGGACGCCTGCGCAAGAAGCTCGGGGTCGACGTCATCCATACGATGCGGGGCCTTGGCT
ATATATTGGCGCCTCCGACGGCGGACGACGGCGCGGCCGCAAGCCGCTCCGAGCCGCCCGCCGGCCGCTGA

Protein sequence : 
MRLLVVEDDKDLNRQIVSALERAGYAVDRAFDGEEGWFLGDTEPYDGVVLDLGLPGKDGVTVLSDWRKAGRVMPVLILTA
RDRWGEKVKGFDAGADDYVTKPFHIEELLARLRALMRRSAGHASSVFSCGPVSFDERGGKVSVEGQPVKLTSHEYRLLGY
LMHHQGKIVSRAEIVEHLYDQDFDRDSNTIEVFVGRLRKKLGVDVIHTMRGLGYILAPPTADDGAAASRSEPPAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 6e-31 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator NC_002516.2.879194.p Protein 7e-39 47
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator CP000647.1.gene1136. Protein 1e-35 46
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator BAC0530 Protein 8e-36 46
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator CP001918.1.gene2526. Protein 7e-34 45
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator CP001138.1.gene1939. Protein 3e-35 45
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator CP000034.1.gene2022. Protein 8e-35 44
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator NC_002695.1.913289.p Protein 8e-35 44
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator BAC0487 Protein 3e-29 44
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator CP004022.1.gene1005. Protein 3e-36 43
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator BAC0111 Protein 1e-28 41
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator BAC0197 Protein 6e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msil_0434 YP_002360770.1 winged helix family two component transcriptional regulator VFG0475 Protein 3e-35 45