Gene Information

Name : Msil_0378 (Msil_0378)
Accession : YP_002360716.1
Strain : Methylocella silvestris BL2
Genome accession: NC_011666
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 416157 - 417761 bp
Length : 1605 bp
Strand : +
Note : TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein; ExsB family protein; KEGG: bid:Bind_2895 GMP synthase, large subunit

DNA sequence :
ATGGCTGAGGACAAGCTCTATGAGACGATCGTCAGACGCCATGACAAGGTCCTGATCGTCGATTTCGGATCGCAGGTCAC
CCAGCTGATCGCGCGCCGCGTGCGCGAGGCCGGCGTCTATTGCGAGATTGCGCCGTTTCAGGCGGCCGAAAAGGCCTTCA
ATGCGCTGAACCCCAAGGCTGTTATCCTCTCGGGCGGCCCCCGATCCGTATTGGAGCCAGATTCGCCGCGCGCGCCCAAA
ACTCTATTCGAGTCCGGTGTGCCCATTCTTGGCATCTGCTACGGCGAGCAGGTCATGGCCGAGCAGCTTGGCGGCACGGT
TATCGCCGGACATAGTCACAGCCGCGAATTCGGCCGCGCCGAAGTCGAGATTTTGCGCGAAAGCGCCCTGTTCGACGGCG
TCTGGGGGCGCGGCAAAAGCTATCCGGTCTGGATGAGCCATGGCGATGCAGTCAGCGAGCTGCCGGAAGGCTTTGTCCCC
ATCGCGACCTCGCCGAGCGCGCCGCTTGCCGCCATCGCCGACGAGGCGCGGAGATTTTTCGGCGTGCAGTTCCATCTCGA
AGTCGCCCACACGCCCGACGGCGCAAAACTCATTTCCAATTTCGTGCATAAGGTCGCCGGGCTCAGCGCCGATTGGACCA
TGGGCGCCTTCCGGCAGGAGGCGATCGCCGCGATCCGCGCGCAAGTCGGCTCGGGGCGCGTGCTGTGCGGCCTTTCCGGC
GGCGTCGATTCGGCGGTGGCGGCGTTGCTCATTTTCGAGGCGATCGGCGAACGGCTGACTTGCGTCTTCGTCGATCACGG
CCTGCTGCGGCAGGGCGAGGCCGAAGAGGTCGTGACCCTGTTTCGCGGCCATTACAATATTCCGCTGCATCACGTCGAGG
CGAAGGCGCTGTTTCTCGGGGCCCTGACCGGCGTCCGCGATCCGGAGGAAAAGCGCAAGATCATCGGGCGTCTTTTCATC
ACCGCTTTCGAGGCGGAGGCGAAAAAGATCGCCGCCGACGGCCGCGGCGCCCCGGAATTTTTGGCGCAGGGAACGCTCTA
CCCGGATGTGATCGAAAGCGTCTCGTTCAGCGGCGGACCTTCGGTCACCATCAAGTCGCATCACAATGTCGGCGGCTTGC
CCGAACGCATGAATATGAAGCTGGTCGAGCCGCTGCGCGAGCTGTTCAAGGATGAAGTGCGCGCGCTTGGCCGCGAGCTC
GGTCTGCCGGAAGCCTTTGTCGGGCGCCATCCCTTCCCGGGGCCGGGGCTGGCGATCCGCTGCCCAGGCGGAATCACGCC
GGAAAAGCTCGAAATCTTGCGCCAGGCCGACGCCATCTATCTCGATGAAATCCGCAAGGCCGGATTATATGACGAGATCT
GGCAGGCCTTCGCCGTGCTGCTGCCCGTGCAGACGGTCGGCGTGATGGGCGACGGTCGCACCTATGAATTCGTCTGCGCC
CTGCGGGCGGTCACCTCGGTCGATGGCATGACGGCCGATTTCTACCCCTTCGGCATGGGATTTCTCGGTCGGGCCGCGAC
ACGGATCGTCAACGAAGTCAAAGGCGTCAACAGGGTTGTCTACGACATAACGTCAAAGCCGCCTGGCACGATCGAGTGGG
AATAG

Protein sequence :
MAEDKLYETIVRRHDKVLIVDFGSQVTQLIARRVREAGVYCEIAPFQAAEKAFNALNPKAVILSGGPRSVLEPDSPRAPK
TLFESGVPILGICYGEQVMAEQLGGTVIAGHSHSREFGRAEVEILRESALFDGVWGRGKSYPVWMSHGDAVSELPEGFVP
IATSPSAPLAAIADEARRFFGVQFHLEVAHTPDGAKLISNFVHKVAGLSADWTMGAFRQEAIAAIRAQVGSGRVLCGLSG
GVDSAVAALLIFEAIGERLTCVFVDHGLLRQGEAEEVVTLFRGHYNIPLHHVEAKALFLGALTGVRDPEEKRKIIGRLFI
TAFEAEAKKIAADGRGAPEFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGREL
GLPEAFVGRHPFPGPGLAIRCPGGITPEKLEILRQADAIYLDEIRKAGLYDEIWQAFAVLLPVQTVGVMGDGRTYEFVCA
LRAVTSVDGMTADFYPFGMGFLGRAATRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-120 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-125 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-125 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-126 52