Gene Information

Name : Msil_2342 (Msil_2342)
Accession : YP_002362634.1
Strain : Methylocella silvestris BL2
Genome accession: NC_011666
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2545397 - 2546917 bp
Length : 1521 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: bid:Bind_2852 aldehyde dehydrogenase

DNA sequence :
ATGGTTGAAAAGCTTCTGGCCGATCTCAAGGATCAGATCGCCATCCGGCCGCACTACGACAATTTCATCGGCGGCAAGTG
GACGCCGCCGGTCAAAGGCCAGAGTTTCGAGAATATCTCGCCGATCGACGGCAATGTCGTCTGCACCATCGCCCGCTCCA
CTGCCGAAGACGTCGAGCTTGCTCTTGACGCCGCGCACGCCGCCCGCGAGAGCTGGGGCAACGCCTCGCCGGCGACGCGG
TCCCTCGTGCTTCTGCGCATCGCCGATCGCATTGAAGAAAAGCTCGATGTGCTGGCGATGGTCGAGACCATCGACAACGG
CAAGCCGATCCGCGAGACCAAGGCGGCCGATCTGCCGCTCGCCGTCGATCACTTCCGCTATTTCGCCGGCGTGCTGCGCG
CCCAGGAAGGCTCGATCAGCGAAATCGACCACGACACCATCGCCTATCATTTCCATGAGCCGCTCGGCGTCGTCGCGCAG
ATCATCCCGTGGAATTTCCCGCTGCTGATGGCGGTGTGGAAGATCGCCCCCGCGCTCGCCGCCGGCAATTGCATCGTCAT
GAAGCCGGCCGAACAGACGCCCATGAGCATCATGGTCCTGATGGACGTGATCGGCGATTTGCTTCCGCCCGGCGTCCTCA
ACGTCATCAATGGTTTCGGCGTCGAATGCGGCAAACCGCTGGCGCAAAGTCCGCGCATCGCCAAGGTCGCCTTCACCGGC
GAAACGACGACCGGCCGCCTCATCATGCAATATGCGTCGGAAAACATCATTCCGGTGACGCTTGAGCTCGGCGGCAAGAG
CCCGAACATCTTCTTCGAGGACGTCGCCGACGAAGACGACGATTATTTCGACAAGGCCCTCGAAGGCTTCGCCATGTTCG
CGCTGAACCAAGGGGAGGTCTGCACCTGCCCCTCCCGCGCGCTGGTGCATGAGAAGATCTACGATCGCTTCATGGAGCGC
GCCATCAAGCGCGTCAACGCGATCAAGCAGGGCAACCCGCTCGATCCCTCGACCATGATCGGCGCACAGGCTTCGAACGA
CCAGCTTGAGAAGATCCTGTCCTATATGGACATCGGCCGCCAGGAAGGCGCCAAGGTGCTCGCCGGCGGCGGCCGCGCGG
ATCTCGGCCCGGAGCTCGCCAACGGCTTCTATGTGCAGCCGACGGTGCTCGAGGGCCACAACAAGATGCGCATCTTCCAG
GAGGAGATCTTCGGACCGGTGCTTTCGGTCACGACCTTCAAGGACGACGCGCAGGCGCTCGAGATCGCCAACGACACGCT
GTACGGCCTCGGTTCGGGCGTATGGACGCGCAACGGCACCCGCGCCTATCGTTTCGGCCGCGCCATCAAGGCCGGCCGCG
TGTGGACCAATTGCTACCACCTCTATCCGGCTCACGCAGCCTTCGGCGGCTACAAGAAGTCCGGCATCGGCCGCGAAAAC
CACAAGATGATGCTGGACCACTATCAGCAGACCAAGAATATGCTGGTCAGCTACAGCAACAAGCCGCTGGGCTTCTTCTG
A

Protein sequence :
MVEKLLADLKDQIAIRPHYDNFIGGKWTPPVKGQSFENISPIDGNVVCTIARSTAEDVELALDAAHAARESWGNASPATR
SLVLLRIADRIEEKLDVLAMVETIDNGKPIRETKAADLPLAVDHFRYFAGVLRAQEGSISEIDHDTIAYHFHEPLGVVAQ
IIPWNFPLLMAVWKIAPALAAGNCIVMKPAEQTPMSIMVLMDVIGDLLPPGVLNVINGFGVECGKPLAQSPRIAKVAFTG
ETTTGRLIMQYASENIIPVTLELGGKSPNIFFEDVADEDDDYFDKALEGFAMFALNQGEVCTCPSRALVHEKIYDRFMER
AIKRVNAIKQGNPLDPSTMIGAQASNDQLEKILSYMDIGRQEGAKVLAGGGRADLGPELANGFYVQPTVLEGHNKMRIFQ
EEIFGPVLSVTTFKDDAQALEIANDTLYGLGSGVWTRNGTRAYRFGRAIKAGRVWTNCYHLYPAHAAFGGYKKSGIGREN
HKMMLDHYQQTKNMLVSYSNKPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-143 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-148 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msil_2342 YP_002362634.1 aldehyde dehydrogenase VFG0082 Protein 5e-144 62