Gene Information

Name : guaA (Sbal223_1380)
Accession : YP_002357311.1
Strain : Shewanella baltica OS223
Genome accession: NC_011663
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1611658 - 1613235 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCGATATTCATGAGCACAAGATACTGATCCTCGATTTTGGATCTCAGTACACTCAACTGATTGCCCGTCGTATCCG
TGAAATCGGTGTGTACTGTGAATTATGGGCTTGGGACGTAACAGAAGCCCAAATCCGCGAATTTGCCCCGAACGGTATTA
TTCTTGCTGGCGGACCTGAAAGTGTAACGGCTGAAAACTCGCCGCGTGCGCCTGAATACGTATTTACTGCGGGCGTGCCT
GTACTGGGCATTTGCTACGGCATGCAAACCATGTCTGAGCAGCTGGGCGGTAAAGTGATCCAAGGTGTGGGTGAAGGTGA
ATTCGGCTACGCTCAAATTGAAATGCTGACAGATTCTTTGCTATTCAAAGGCATCGAAGACGCAGTTAATAGCGAAGGCA
AACCCTTACTCGACGTATGGATGAGCCACGGCGATAAAGTGTCGGCCATTCCTGAAGGGTTTGTGGCAGTTGCTAAAACG
GACACTTGCCCATTTGCTGCTATGGCAAACGAAGAGAAGCAATTCTTCGGCGTACAGTTCCACCCTGAAGTTACCCACAC
TCGCCAAGGCATGCGCATGTTATCGCACTTTGCCTTAGACATTTGTGGCTGTGCGGCTAACTGGAAACCTTCCTCTATCA
TCGAAGATGCGATTGAGCGCTTGAAGAAGCAAATCGGCGATGATGAAGTGATTTTAGGGCTATCGGGCGGTGTCGATTCT
TCGGTTGTGGCTATGTTGCTGCACCGCGCTATCGGTAAAAAACTGACCTGCGTATTCGTTGATAACGGTTTATTGCGTTT
GAACGAAGCCGAGCAAGTGATGGAAATGTTTGGCGATCATTTTGGTCTGAACATTATTCATGTTGATGCGGAAAATCGCT
TCCTTGACGCGATGAAAGGCGAAGCCGATCCAGAAGCTAAGCGTAAGATCATCGGCCGTGTATTCGTGGAAATTTTCGAT
GAAGAATCGAAAAAATGCGCCAATGCCAAATGGTTAGCGCAAGGCACGATTTATCCAGACGTGATTGAATCTGCTGGCAG
CGCCACAGGTAAAGCACATGTGATCAAGTCGCACCATAACGTTGGCGGTTTACCTGACCATATGGAACTGGGTTTAGTTG
AGCCACTGCGCGAACTGTTTAAAGATGAAGTGCGCAAAATTGGTCTTGAGTTAGGTCTGCCATATAATATGCTTTATCGT
CACCCGTTCCCAGGACCAGGTCTTGGTGTGCGTGTATTAGGTGAAGTGAAGAAAGAATACTGTGACTTATTGCGCCGCGC
CGATGCTATCTTCATTGAAGAACTGCATAAAGCCGACCTGTACAATAAAGTCAGCCAAGCCTTTACCGTGTTCTTACCTG
TACGCTCAGTCGGTGTTATGGGTGATGGCCGTAAATATGATTGGGTTGTGTCACTGCGCGCCGTTGAAACCGTTGATTTT
ATGACGGCCCATTGGGCACATCTGCCGTATGATTTCTTAGGTCGCGTATCAAACCGCATCATCAACGAAGTCGATGGCAT
TTCCCGCGTGGTTTACGATATCTCTGGCAAGCCGCCAGCGACTATCGAATGGGAATAA

Protein sequence :
MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFTAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTDSLLFKGIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKT
DTCPFAAMANEEKQFFGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDS
SVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVDAENRFLDAMKGEADPEAKRKIIGRVFVEIFD
EESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDHMELGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-124 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-124 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-124 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-109 47