Gene Information

Name : Tmz1t_0990 (Tmz1t_0990)
Accession : YP_002354652.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1090773 - 1092788 bp
Length : 2016 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGCGTGTTCCTGTGCGAGAAGCCCTCCCAGGGCAAGGACATCGCCCGTGTGCTGGGTGCCGTTCAACGCGGCAACGG
CTGCTACAGCGGCGCGGGTGTCGTCGTGACCTGGTGCATCGGTCATCTGGTGGAGGCGGTTCCGCCCGAAGGCTACGGCG
AGCAATACAAGCGCTGGGCCATCGAGCAACTGCCCATTCTTCCTGAGCGTTGGCGTGTCGAGCCCAAGGCGGCGACCGCA
GCGCAATTCAAGGTCGTGCAGCAGCTCGTCGCCAAGGCGGGCGAGCTGGTGATAGCGACCGACGCCGACCGCGAGGGCGA
GATGATCGCCCGCGAGATCATCGACCTGTGCGGCTACCGCGGGCCGATTCAGCGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCGATCCGCAAGGCACTGGGTGCGCTCAAGCCGTCCGCCGAGACGCTGCCGCTGTATTTCTCCGCACTCGCCCGATCG
CGCGCCGACTGGCTGATCGGGATGAACTTGAGCCGCTTGTTCACACTGCTGGGGCGTCAGGCCGGCTATACGGGCGTGCT
GTCGGTGGGGCGCGTGCAGACGCCGACGCTGAAGTTGGTCGTGGATCGTGATCGCGAGATCGCGCGATTCGTCTCCATGC
CGTATTGGGCCGTGGATGTGCTGCTATCCCATGCCGGCCAATCCTTCACCGCGAGCTGGATACCGCCCGAAGGCAGCACG
GATGCAGCGGGTCGCTGCCTTCAGCAGCCGGTGGCGCAGCAGGCTGCGGATCGCATTCGCGCGGCACGCGATGCGCAGGT
CGTGTCGGTGGACACCGAGCGCGTGCGCGAGGCACCGCCGCTGCCGTTCGACCTGGGCACGCTGCAGGAGGTGTGCTCCA
AGCAGTTGGGCCTCGACGTGCAGGAGACGCTGGACATTGCCCAGGCGCTGTACGAGACGCACAAGGCGACAACGTATCCG
CGCTCGGATTCGGGCTACCTGCCCGAGAGCATGCTGGCCGAGGTGCCGACCGTACTCGACAGTCTGGTCAAGACCGACCC
CAGCCTGCGGCCGCTGATCGAGCGCCTGGATCGCCAACAGCGCTCGCGTGCATGGAACGACGGCAAGGTGTCGGCTCACC
ACGGCATCATCCCGACGCTGGAGCCCGCCAACCTGTCGGCCATGAACGAGAAGGAACTGGCCGTCTACCGGCTGATCTGC
GCCCATTACCTCGCGCAGTTCCTCCCGCACCATGAGTTCGACCGGACGGTAGCGCAGTTCTCGTGCGGCAGTCAGTCGCT
GGCGGCCGTGGGCAAGCAGATCGCCGTCACCGGCTGGCGTGAGGTGCTGGCGACGCCGGGGCCGGACGATGCCGATGGCG
AGGATGCGCAGCGCAGCCAGGTGCTGCCCGCCCTGCATGCGGGCCTGTCCTGCCCGGTCGGCAAGGTGGATCTCAAGGCG
CTGAAGACGCTGCCGCCCAAACCCTACACGCAGGGCGAGCTGATCAAGGCCATGAAGACCGTCGCCAAGTTCGTGACCGA
CCCGCGCCTGAAACAGAAGCTGCGAGATACCACCGGCATCGGCACCGAGGCGACACGCGCCAACATCATCAACGGTCTGA
TCGGTCGCGGCTACCTGGTCAAGAAAGGCCGCGCCGTCCGCGCTTCCGACGCGGCATTCACGCTCATCGACGCGGTGCCC
TCGGCCATCGCCGACCCCGGCACCACGGCGGTGTGGGAGCAGGCGCTCGACATGATCGAGGCCGGCCAGATGGCGCTGGA
CACCTTCATCGAGAAGCAGTCCGTGTGGGTCGGCCAGCTCGTGCAGCAGTACCGCGGCGCGACGCTCTCGCTCAAGCTGC
CGCCGGCGCCGGCCTGCCCGCAGTGCGGCGCACCGATGCAGCAGCGCACGGGCAAGAGCGGCGCGTTCTGGTCCTGCTCG
CGCTACCCGGACTGCAAGGGCACGTTGCCGCTCGAGTCCCCGACGGGCCGGCGCAGCGCACCGCGCAAGCGGCGCGCTGC
CTCCAAGGCGTCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGAVQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPILPERWRVEPKAATA
AQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCGYRGPIQRLWLSALNDASIRKALGALKPSAETLPLYFSALARS
RADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVSMPYWAVDVLLSHAGQSFTASWIPPEGST
DAAGRCLQQPVAQQAADRIRAARDAQVVSVDTERVREAPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMLAEVPTVLDSLVKTDPSLRPLIERLDRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIC
AHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVTGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA
LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLVKKGRAVRASDAAFTLIDAVP
SAIADPGTTAVWEQALDMIEAGQMALDTFIEKQSVWVGQLVQQYRGATLSLKLPPAPACPQCGAPMQQRTGKSGAFWSCS
RYPDCKGTLPLESPTGRRSAPRKRRAASKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 80
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 79
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 65
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 6e-158 51
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-158 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 6e-158 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-158 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 7e-159 50