Gene Information

Name : Tmz1t_0766 (Tmz1t_0766)
Accession : YP_002354433.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 850993 - 852495 bp
Length : 1503 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: azo:azo2250 succinate semialdehyde dehydrogenase [NAD(P)+]

DNA sequence : 
ATGGACCGATACAAGGGTGAACTGCTGAGCGACGACACGCGCCGGTTCCTGGCGCAGCCCAAGCGCATGGCGATCGGCGG
CGAATGGGTGGAGGCCCTCGGCGGTGGCATGCTCGAGGTGGTGGATCCCGCCAGCGGGCAGGTGTTCGATCGCGTGCCGG
CGGGCGAGGCGACCGACATCGACCGCGCGGTGGCGGCGGCGCGGCGCGCCTTCGAGCAGGGCGACTGGCCGCGCATGCGA
CCGGTGGACCGCGAGCGCCTGCTGCTGCGCCTGGCCGAGCTGGTGGAGGCGCATGCGCAGGAACTGGCCGAGATCGAGGC
GCTCGACAACGGCAAGCCGGTGACCATGGCGCGTGCGGTCGACGTGGCGCTGGTGGTGGACTTCCTGCGCTACATGGCCG
GCTGGGCGACCAAGATCGAAGGCTCGACGATGGAGGTGTCGGTCCCCCTGGTGCGCGACCGCGAGTTCTTCGGCTACACC
CGGCGCGAGCCGGTGGGCGTGGTGGGGGCGATCATCCCGTGGAACTTCCCGCTGCTGATGGTGGCGTGGAAGGCGGGGCC
GGCACTCGCCTCCGGGTGCACGATGGTGCTCAAGCCCGCCGAGGAGACGCCGCTGTCGGCGCTGCGCTTTGCCGAGCTGG
TGCAGCAGGCGGGCTACCCCGCGGGGGTGTTCAACGTCGTCACCGGCCACGGCCACTCCGCGGGTGCGGCGCTGGCCGCG
CACAAGGGCGTCGACAAGGTGGCCTTCACCGGCTCGACCGAGATCGGCAAGCTGGTCGGCAAGGCCGCGCTCGACAACAT
GACGCGGGTGTCGCTGGAGCTGGGCGGCAAGAGCCCGGTGATCGTGCTCGACGACGCCGACCCGGCGGTAGCGGCTGCGG
GCGCGGCGCAGGCGATCTTCTTCAACCAGGGGCAGGTGTGCTGCGCGGGTTCGCGCCTGTATGTGCACAAGAGTCGTTTC
GAGCGCGTGGTGGAGGGGCTGTCGGGGATCGCCGCGGACATGAAGCTCGGCGCCGGCATCGAGCCCTCGACGCAGATCGG
CCCGCTGGTGTCGGCCGTCCAGCAGCAGCGCGTGCTGGGCTACATCCGCAGCGGCTTCGAGGAGGGCGCGCGCGCGCTGG
CGGGCGGCGCAGCGGGCGAGGGCGAGGGCTACTTCGTCAAGCCGACGGTGCTGGTCGATACCCGCGACGACATGCGCGTG
GTGCGCGAGGAGATCTTCGGCCCGGTGGTGGTGGCGATGCCCTACGACGATCTCGACGAGGTCGCCCGCCGCGCCAACGA
CACCCCATACGGCCTCGGCGCCAGCATCTGGTCCAACGACCTGTCGCGGGTGCACCGCCTGGTGCCGAAGATCAAGGCCG
GTACGGTGTGGGTCAACTGCCACAACATCCTCGACGCCTCGATGCCCTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGC
GAGATGGGGCGCGCGGTGCTCGACCTGTACACCGAGGGCAAGTCGGTGATCATGGCCCTGTAA

Protein sequence : 
MDRYKGELLSDDTRRFLAQPKRMAIGGEWVEALGGGMLEVVDPASGQVFDRVPAGEATDIDRAVAAARRAFEQGDWPRMR
PVDRERLLLRLAELVEAHAQELAEIEALDNGKPVTMARAVDVALVVDFLRYMAGWATKIEGSTMEVSVPLVRDREFFGYT
RREPVGVVGAIIPWNFPLLMVAWKAGPALASGCTMVLKPAEETPLSALRFAELVQQAGYPAGVFNVVTGHGHSAGAALAA
HKGVDKVAFTGSTEIGKLVGKAALDNMTRVSLELGGKSPVIVLDDADPAVAAAGAAQAIFFNQGQVCCAGSRLYVHKSRF
ERVVEGLSGIAADMKLGAGIEPSTQIGPLVSAVQQQRVLGYIRSGFEEGARALAGGAAGEGEGYFVKPTVLVDTRDDMRV
VREEIFGPVVVAMPYDDLDEVARRANDTPYGLGASIWSNDLSRVHRLVPKIKAGTVWVNCHNILDASMPFGGYKQSGIGR
EMGRAVLDLYTEGKSVIMAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 8e-69 45
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-65 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-68 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-68 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-68 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmz1t_0766 YP_002354433.1 betaine-aldehyde dehydrogenase VFG0082 Protein 4e-65 42