Gene Information

Name : Tmz1t_2872 (Tmz1t_2872)
Accession : YP_002889848.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD(+))
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3108790 - 3110310 bp
Length : 1521 bp
Strand : -
Note : PFAM: aldehyde dehydrogenase; KEGG: dar:Daro_1008 aldehyde dehydrogenase

DNA sequence :
ATGCTGTACGCACTGCCCGGCCAGGCCGAAGCCAAGGTTCAGTTCAAGACCCGCTACGACAACTTCATTGGTGGCAAGTG
GGTGGCCCCGGTCAAGGGCCAGTATTTCGATGTGGTGACCCCGATCACCGGCCAGAAGTACACCCAGGCCGCGCGTTCCA
CCGCCGAGGACATCGAGCTCGCCCTCGACGCCGCGCACGCAGCCTTCCCCAAGTGGGGCAAGGCCGACGCCACCACCCGT
TCGAACATCCTGCTCAAGATCGCCGACCGCCTCGAGGCCAACCTCGAGCTGCTCGCCTACGCCGAGACCGTCGATAACGG
CAAGCCGATCCGCGAGACGCTCAACGCCGACATCCCGCTCGCCGTCGACCACTTCCGCTACTTCGCCGGCTGCCTGCGCT
CGCAGGAAGGCGGCATCTCGGAGATCGACGAGAACACCATGGCCTATCACATCCACGAGCCCCTGGGCGTGGTCGGCCAG
ATCATCCCGTGGAACTTCCCCATCCTGATGGCGGCGTGGAAGCTGGCGCCGGCGCTGGGTGCGGGCAACTGCGTGGTGCT
CAAGCCCGCCGAGTCGACCCCGATCTCGATCCTGGTGCTGATGGAGCTGATCGCCGACCTGCTGCCGCCGGGCGTGCTCA
ACATCGTCAACGGCTACGGCCGCGAGGCCGGCATGCCGCTCGCCACCAGCAAGCGCATCGCCAAGATCGCCTTCACCGGC
TCCACCTCCACCGGCCGCGTGATCGCCCAGGCCGCCGCCAACAACCTGATCCCGGCCACGCTCGAACTGGGCGGCAAGTC
GCCCAACATCTTCTTCGCCGACGTCATGGACAAGGACGACGCCTTCCTCGACAAGGCGATCGAGGGCCTGGTGCTGTTCG
CCTTCAACCAGGGCGAGGTGTGCACCTGCCCGAGCCGCGCGCTGATCCAGGAATCGATCTACGACCGCTTCATGGAGCGT
GCTCTGAAGCGCGTCGCCGCGATCAAGCAGGGCAGCCCGCTCGACACCGACACCATGATGGGCGCGCAGGCCTCCGCCGA
GCAGATGAGCAAGATCCAGTCGTATCTGCAGCTCGGCAAGGAAGAGGGCGCCCAGGTGCTGATCGGCGGTGCGCGCGCCC
AACTCGGCGGCGACCTGGCCGACGGCTTCTATATCCAGCCGACGCTGTTCAAGGGCCACAACAAGATGCGCATCTTCCAG
GAGGAGATCTTCGGGCCGGTGCTCGCGGTGACCACCTTCAAGGACGAGGCCGAGGCCCTGGCGATCGCAAATGACACCCT
GTATGGTCTGGGCGCCGGCGTGTGGAGCCGCAACGGCAACGTCGCCTACCGCATGGGCCGCGCCATCCAGGCCGGGCGCG
TGTGGACCAACTGCTACCACGCCTACCCGGCGCACGCGGCCTTCGGCGGCTACAAGGAGTCGGGCATCGGCCGCGAGACG
CACAAGGTCATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACAGCGAGAACAAGCTCGGCTTCTTCTG
A

Protein sequence :
MLYALPGQAEAKVQFKTRYDNFIGGKWVAPVKGQYFDVVTPITGQKYTQAARSTAEDIELALDAAHAAFPKWGKADATTR
SNILLKIADRLEANLELLAYAETVDNGKPIRETLNADIPLAVDHFRYFAGCLRSQEGGISEIDENTMAYHIHEPLGVVGQ
IIPWNFPILMAAWKLAPALGAGNCVVLKPAESTPISILVLMELIADLLPPGVLNIVNGYGREAGMPLATSKRIAKIAFTG
STSTGRVIAQAAANNLIPATLELGGKSPNIFFADVMDKDDAFLDKAIEGLVLFAFNQGEVCTCPSRALIQESIYDRFMER
ALKRVAAIKQGSPLDTDTMMGAQASAEQMSKIQSYLQLGKEEGAQVLIGGARAQLGGDLADGFYIQPTLFKGHNKMRIFQ
EEIFGPVLAVTTFKDEAEALAIANDTLYGLGAGVWSRNGNVAYRMGRAIQAGRVWTNCYHAYPAHAAFGGYKESGIGRET
HKVMLDHYQQTKNLLVSYSENKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-151 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-161 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-161 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-161 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-161 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmz1t_2872 YP_002889848.1 aldehyde dehydrogenase (NAD(+)) VFG0082 Protein 4e-152 64