Gene Information

Name : Tmz1t_2714 (Tmz1t_2714)
Accession : YP_002889693.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2942913 - 2945966 bp
Length : 3054 bp
Strand : -
Note : PFAM: acriflavin resistance protein; KEGG: vco:VC0395_A1355 transporter AcrB/D/F family

DNA sequence :
ATGAACATCGCCGAGTACACGATCCGCAAGTCCGTCGTCGCCTGGGTGGCCACGCTGCTGGTGCTGGCGGGCGGCTGGCT
GGCCTACGAGCGCCTCGGCCGCTTCGAGGATCCGGAGTTCGTCATCCGCCAGGCGGTGGTCGTCACCGCCTACCCCGGTG
CCTCGCCGGCGCAGGTGGCCGAGGAGATCACCGACCGCATCGAGGGCGCGGTGCAGCAGATGCAGGAGGTGGAGGAGGTC
GTCTCGGTGTCGCGCGCCGGCGAGTCGCTGGTGAAGGTGGAGGCCAGGCTCGCCTTCTCGCATACCCAGGCCGAGCTCGA
CCAGGTGTGGGACAAGCTGCGCGGCAAGATCGCCGAGGCCGCGCGCGCCCTGCCGCCGGGTGCGGCCGAGCCGGTGGTGA
AGGGCGACTTCGGCGACGTCTTCGCGCTCTTCTACGCGGTCACCGGCGAGGGCTACAGCCCGCGCCAGCTCTATGACTAC
GTCGACCTGCTGCGCCGCGAGCTGGTGCTGGTGCCGGGCGTGGCGCGGGTGGCGCTGCTGGGCGAGCGCAGGGAGGCGAT
CTACGTCGAGGTCTCGAGCGCGCGCGCCGCGCAGCTCGGCGTGCCGCTCGAGCGCATCTACGCCTCGCTGCGCACGCAGA
ACCTGATCGCGCCCGCCGGTGCGGTCGATGCCGGCCCGCTGCGCCTGCAGATCCAGCCGGCGGACGGCGTGGTCTCGGTG
GCGGCGCTCGGCGAGCTGGTGGTGGCGGGCGACGCCGCGAGCGGCCTGCTGCGTCTGCGCGACGTGGCCGAGATCCGCCG
CGAGTACGTCGACCCGCCCGCGGTGCTGATGCGCCATGACGGCCAGGCGGCGATCGGACTGGGCATCTCCAACGTGCTCG
GCGGCAACGTGGTGGAGATGGGCGACGCGGTCAAGCGCCGCCTCGCCGAGCTCGAAGGCCAGCGTCCGGTGGGCATGGAG
CTGAACGTGGTCTCCTTCCAGTCCGATTCTGTGCGCGCCGCGGTGGCGGGCTTCGTGGACAACCTGGTGGCGGCAGTGGC
GATCGTGGTCGTGGTGCTGCTGCTCTTCATGGGCCTGCGCAGCGGGCTGATCATCGGCGCGGTGCTGGTGCTGACTGTGG
CCGGCACGCTGATCGCGATGTGGATGGACGGCATCGCCATGCAGCGCATCTCGCTCGGCGCGCTGATCATCGCGCTCGGC
ATGCTGGTGGACAACGCGATCGTGGTCACCGACGGCATCCTGGTGCGGATGCAGAAGGGCGAGGCGGTGGGCCCGGCTGC
GGGTGCCGTGGTGCGTGGGACGGTGTGGCCGCTGCTCGGCGGCACCGTGGTCGGCATCCTCGCCTTCAGCGCGATCGGCC
TGTCGCCCACCGACATGGGGGAGTACGCCGGCTCGCTGTTCTGGGTGATCCTGTACTCGATGCTGCTGTCGTGGCTGTTC
GCGATCACGCTGACGCCGCTGCTGTGCGCCGCCTTCCTGAAGGTGAAGGTGGAGGCGGGTGCGCGGGAGGGTGGCCTGCT
GCGCGCCTATCGCCGCCTGCTGCAGGGCGTGCTGGCCCGGCGCGTGGCGAGCGGCGTGGTGCTGCTGGGGTTGCTCGCCG
CCGGCGTGCTCGCCTTCGGTCACGTGCCACCGGGATTCATGCCCGATTCGGCGCGGCCGCAGTTCGTCGTCGACCTGGCG
CTGCCGCAGGGTACCGACATCCGAACCACTGCCGCCGTGGTCGCCGAGGCCGAGGCGAAGGTGAGCGCGGCGCCGGGCGT
GAGCCATGTGACGAGCTTCATCGGCCAGGGCGGGCTGCGCTTCATGCTCACCTACAGCCCGGAAGACCCCAACCCGGCCT
ATGGCCAGCTCTTGGTCGATGTCGAGCGCTTCGAGGACATCGCCGGCCTCATCGAGCGCCTGCAGCCCGAGCTCGAGGCC
GCCTTCCCGCAGGCCAGCGTCAAGGTGTGGAAGTTCATGCTCGGCCGCGGCGGCGGCAAGAAGATCGAGGCCGCCTTCCG
CGGCCCCGACCCGGCGATGCTGCGCCGGCTGGCGGAAGAGGCCAAGGCGATCATGGCCGCCGACCCCGGGGCGGTGGCGA
TCCAGGACGACTGGCGCCAGGCGGTGCCAGTGGTGCGCCCGCACTTCTCGGTCGAGGCCGCGCAGCGCGCCGGCGTCCTG
CCCTCGGACATCGCCGCCGCGCTCGAGCGCACCTACGTCGGCCAGAACATCGGCGTGTATCGCGACAAGGAGCGTCTGAT
CCCCATCCTGGCGCGCGCGCCGGCGGACGAGCGCGGCGGCGTCGAGGATCTCGGCAACGCCCAGGTCTTCAGTGCGACCG
CCGGCAAGTGCGTGCCGGTGAGCCAGTTCGTCGAGCGCGTCGACACGGTGTGGGAGGACGCGCTGATCCGGCGCGAGAAC
CGCTTCCCGACCATCAAGGCGCAGTGCGACCCGCCCGCAGGGCAGCTGTCCGCGCCGCTGTTCGAGCGCCTGCGCCCGCA
GATCGAGGCCATCACGCTGCCGCCAGGCTATGTTTTGGAGTGGCACGGCGAGCACAAGGCCTCGGTCGAGGCCAACGCCG
GCCTGGCCGCGGCGGCGCCCTTCGGCTTCGCGGCGATGGTGGTGGCGGTGATCGTGATGTTCAATGGCCTGCGCCAGACC
GCGGTGATCTGGCTCACCGTGCCGCTGGCGGTGGTGGGGGTGGCGATCGGGCTGCTGCTGTTCCAGGCGCCCTTCGAGTT
CATGGCCATCCTCGGCTTCCTGAGCCTCACCGGCATGCTGATCAAGAACGCGATCGTGCTGGTGGACCAGATCGACGTCG
AGATCCGGGAGGGCAAGCCGCGCCTGCTCGCGCTGCTCGACGCGTCGGCCAGCCGGGCACGCCCGGTCTTCCTCGGCGCG
GTCACGACGGTGCTGGGGGTGGCGCCGCTGCTGGTCGATCCCTTCTTCCGCAGCATGGCGGTGACCATCATGTTCGGCCT
CATCTTCGCCACCGGACTCACCCTGGTGGTGGTGCCGCTGCTGTACGCAAGCTTCTTCCGCATCCGCGGCGACGAGGCGG
AGGCGGGGCGATGA

Protein sequence :
MNIAEYTIRKSVVAWVATLLVLAGGWLAYERLGRFEDPEFVIRQAVVVTAYPGASPAQVAEEITDRIEGAVQQMQEVEEV
VSVSRAGESLVKVEARLAFSHTQAELDQVWDKLRGKIAEAARALPPGAAEPVVKGDFGDVFALFYAVTGEGYSPRQLYDY
VDLLRRELVLVPGVARVALLGERREAIYVEVSSARAAQLGVPLERIYASLRTQNLIAPAGAVDAGPLRLQIQPADGVVSV
AALGELVVAGDAASGLLRLRDVAEIRREYVDPPAVLMRHDGQAAIGLGISNVLGGNVVEMGDAVKRRLAELEGQRPVGME
LNVVSFQSDSVRAAVAGFVDNLVAAVAIVVVVLLLFMGLRSGLIIGAVLVLTVAGTLIAMWMDGIAMQRISLGALIIALG
MLVDNAIVVTDGILVRMQKGEAVGPAAGAVVRGTVWPLLGGTVVGILAFSAIGLSPTDMGEYAGSLFWVILYSMLLSWLF
AITLTPLLCAAFLKVKVEAGAREGGLLRAYRRLLQGVLARRVASGVVLLGLLAAGVLAFGHVPPGFMPDSARPQFVVDLA
LPQGTDIRTTAAVVAEAEAKVSAAPGVSHVTSFIGQGGLRFMLTYSPEDPNPAYGQLLVDVERFEDIAGLIERLQPELEA
AFPQASVKVWKFMLGRGGGKKIEAAFRGPDPAMLRRLAEEAKAIMAADPGAVAIQDDWRQAVPVVRPHFSVEAAQRAGVL
PSDIAAALERTYVGQNIGVYRDKERLIPILARAPADERGGVEDLGNAQVFSATAGKCVPVSQFVERVDTVWEDALIRREN
RFPTIKAQCDPPAGQLSAPLFERLRPQIEAITLPPGYVLEWHGEHKASVEANAGLAAAAPFGFAAMVVAVIVMFNGLRQT
AVIWLTVPLAVVGVAIGLLLFQAPFEFMAILGFLSLTGMLIKNAIVLVDQIDVEIREGKPRLLALLDASASRARPVFLGA
VTTVLGVAPLLVDPFFRSMAVTIMFGLIFATGLTLVVVPLLYASFFRIRGDEAEAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmz1t_2714 YP_002889693.1 acriflavin resistance protein BAC0425 Protein 0.0 62
Tmz1t_2714 YP_002889693.1 acriflavin resistance protein BAC0428 Protein 2e-161 47
Tmz1t_2714 YP_002889693.1 acriflavin resistance protein BAC0519 Protein 2e-158 46
Tmz1t_2714 YP_002889693.1 acriflavin resistance protein BAC0526 Protein 2e-141 41