Gene Information

Name : lysS (Tmz1t_1957)
Accession : YP_002355604.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2201649 - 2203190 bp
Length : 1542 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCCGACCAGACGCAGACCACGCCCCAGCCCCAGGACGAAAACCACCTCATCGCCGAGCGCCGCGAGAAACTCGCCGC
CTGGCGCGCGAGCGGCGGTGCCTTCCCCAACGATTTCTCGCGCGAGAACACCGCCGGCAAGCTCGACGAGCTCTACGGCG
ACAAGGACGCCGAGGCGCTGGAAGCGACGCCGGTCGAGGTCAGGGTGGCCGGCCGCATCATGTTGAAGCGCATCATGGGC
AAGGCGAGCTTCGTCACCATCCAGGACCTCTCCGGCCGCATCCAGCTCTACGTGCAGCGCGACGGCGTGGGCGAGGACGT
CTATGCCCAGTTCAAGACCTGGGACATCGGCGACATCGTCGGCTGCGTGGGCACGGTGTTCAAGACCAAGACCGGCGAAC
TCACCGTCAAGGCCGCGGAGATCCGCCTGCTCACCAAGAGCCTGCGCCCGCTGCCCGACAAGTTCCACGGCCTCACCGAC
GTCGAGCAGAAGTACCGCCAGCGCTATGTCGACCTGATCATGAACGAGCAGTCGCGCTTCACCTTCGTGGCGCGCAGCCG
CATGGTGCAGTCGATCCGCAACTACATGACCGGCCACGGCTTCCTCGAGGTCGAGACGCCGATGATGCACCCCATCCCGG
GCGGTGCCGCGGCCAAGCCCTTCACCACCCACCACAATGCGCTCGACATGGAGCTCTTCCTGCGCATCGCGCCCGAGCTC
TACCTCAAGCGCCTGGTGGTGGGCGGCCTGGAGAAGGTCTTCGAGGTCAACCGCAACTTCCGCAACGAAGGTCTCAGCCC
GCGCCACAACCCCGAATTCACCATGATGGAGTTCTACGAGGCGTACGCGAACTACAAGACGCTGATGGACTTCACCGAGG
GCCTGATCCGCCACGCCGCGCGCGAGGCGCTGGGCACCGAATCCTTCGTCTATCAGGGCCGCGAGCTCGACCTGTCGAAG
CCCTTCCACCGCCTCACCATCGTGCAGGCGATCCGCAAGTACCACCCGGGCTTCACCGCGGAACAACTGGCCGACGCCGC
GTGGCTGAAGGAAAAGATCGTCGCCTTCGGCGAGAAGGTCAAGCCGGGCGGCCTGGGCAGCCTGCAGCTGCAGCTCTTCG
AAGCCTGCGCCGAGGCCGAGCTGTGGGAGCCGACCTTCATCATCGACTACCCGGTCGAGGTCTCGCCGCTGGCGCGCGCG
TCCGACACCGACCCCGAGATCACCGAGCGCTTCGAGCTCTTCATCGTCGGCCGCGAGATCGCCAACGGCTTCTCCGAGCT
CAACGACCCCGAGGACCAGGCCGCGCGCTTCCGCGCCCAGGTCGAGGCCAAGGAAGCGGGCGACGAGGAGGCCATGTATT
ACGACGCCGACTACATCCGCGCGCTCGAATACGGCCTGCCCCCGACCGGCGGCTGCGGCATCGGCATCGACCGCCTGGTG
ATGCTGCTCACCGACGCGCCGGCGATCCGCGACGTGATCCTGTTCCCGCAGATGCGCCCCGAGGCCGCTGCGGGCCTGGT
CATCCCGGAACCCGAGCTCTGA

Protein sequence :
MSDQTQTTPQPQDENHLIAERREKLAAWRASGGAFPNDFSRENTAGKLDELYGDKDAEALEATPVEVRVAGRIMLKRIMG
KASFVTIQDLSGRIQLYVQRDGVGEDVYAQFKTWDIGDIVGCVGTVFKTKTGELTVKAAEIRLLTKSLRPLPDKFHGLTD
VEQKYRQRYVDLIMNEQSRFTFVARSRMVQSIRNYMTGHGFLEVETPMMHPIPGGAAAKPFTTHHNALDMELFLRIAPEL
YLKRLVVGGLEKVFEVNRNFRNEGLSPRHNPEFTMMEFYEAYANYKTLMDFTEGLIRHAAREALGTESFVYQGRELDLSK
PFHRLTIVQAIRKYHPGFTAEQLADAAWLKEKIVAFGEKVKPGGLGSLQLQLFEACAEAELWEPTFIIDYPVEVSPLARA
SDTDPEITERFELFIVGREIANGFSELNDPEDQAARFRAQVEAKEAGDEEAMYYDADYIRALEYGLPPTGGCGIGIDRLV
MLLTDAPAIRDVILFPQMRPEAAAGLVIPEPEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-135 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002355604.1 lysyl-tRNA synthetase VFG1668 Protein 3e-135 58