Gene Information

Name : Tmz1t_1768 (Tmz1t_1768)
Accession : YP_002355416.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1989949 - 1991241 bp
Length : 1293 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATATCCAGCTTCTCCGCACCCAGCTCGACCACGTCGCCGCACGCCTCGCCACGCGCGGGCTGGAGCTCGACAC
CGCCGCCTTCCAGGCCCTCGAGGACGAGCGCAAGCAGTTGCAGACCCGCACCCAGGAACTGCAGGCCCGCCGCAACGCGC
TGTCCAAGCAGATCGGCATGCTCAAGGGCAAGGGCGAGGACGCCTCCGCGGTGATGGCCGAGGTCGCCCAGCTCGGCGAC
GGGCTCAAGGCCTGCGAGCAGGCCCTGCCGATGCTGCTCGAGCGCATCAACGCCTTCCTGGCCACCCTGCCGAACCTGCC
GCAGGACGATGTTCCGGCGGGCGCAGACGAGACCGGCAACGTCGAGGTGCGGCGCTGGGGTACGCCGCGCGCCTACGACT
TCGAGGTGCGCGACCACGTGGACCTCGGCGCTCCGCTCGGCCTCGACTTCGAGACCGGCGCCAAGCTGTCGGGCTCGCGC
TTCGCCTTCCTGCGCGGTCCGGTGGCGCGCCTGCATCGCGCGCTCGCGCAGTTCATGCTCGACACCCACACCCGCGAGCA
CGGCTACACCGAGTGCTACACGCCCTACATCGTCAATGGCTCGGCGCTCTACGGCACCGGTCAGCTGCCCAAGTTCAAGG
AGGATCTGTTCTGGGTGCTGCGCGGCGGCGACGAGGAGGGCCTCGAGCAGTACCTGATCCCGACCGCAGAGATCACGCTC
ACCAACAGCGTGCGCGAGGAGGTGCTCGCGCTCGAGAGCCTGCCGATCCGTCTTACCGCGCATAGCCCCTGCTTCCGCTC
CGAGGCGGGCAGCGGCGGGCGCGACGTGCGCGGCATGATCCGCCAGCACCAGTTCGACAAGGTCGAGATGGTGCAGATCG
TCGAGCCGGCGAAGAGCAAGGAGGCGCTCGAACAGATGGTCGGCCACGCCGAGGCCATCCTGCAGAAGCTCGAGCTGCCC
TACCGGGTGATCACGCTGTGCACCGGCGACATGGGCTTCTCGGCTGCGAAGACCTACGATCTCGAGGTGTGGCTGCCGGC
GCAGAACACATACCGCGAGATCTCCAGCTGCTCGAACTGCGAGTCCTTCCAGGCGCGTCGCATGCAGGCCCGCTTCAAGA
ACGCGCAGGGCAAGAACGAGCTGGTGCACACGCTCAACGGGTCCGGTCTGGCGGTGGGGCGCACCCTGGTTGCGGTGCTG
GAGAACCACCAGCAGGCCGACGGTTCGATCGTGATCCCGCGGGCGCTGGTGCCCTACATGGGTGGCATCGAGCGCATCGA
AGCGCCGCTCTGA

Protein sequence :
MLDIQLLRTQLDHVAARLATRGLELDTAAFQALEDERKQLQTRTQELQARRNALSKQIGMLKGKGEDASAVMAEVAQLGD
GLKACEQALPMLLERINAFLATLPNLPQDDVPAGADETGNVEVRRWGTPRAYDFEVRDHVDLGAPLGLDFETGAKLSGSR
FAFLRGPVARLHRALAQFMLDTHTREHGYTECYTPYIVNGSALYGTGQLPKFKEDLFWVLRGGDEEGLEQYLIPTAEITL
TNSVREEVLALESLPIRLTAHSPCFRSEAGSGGRDVRGMIRQHQFDKVEMVQIVEPAKSKEALEQMVGHAEAILQKLELP
YRVITLCTGDMGFSAAKTYDLEVWLPAQNTYREISSCSNCESFQARRMQARFKNAQGKNELVHTLNGSGLAVGRTLVAVL
ENHQQADGSIVIPRALVPYMGGIERIEAPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-108 56