Gene Information

Name : thyA (Tmz1t_1592)
Accession : YP_002355246.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1776441 - 1777235 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGACAGTACCTCGACCTGATGCGCCATGTGCTCGAGCACGGCGACCCCAAGACCGACCGCACCGGCACCGGAACCCT
GTCGGTGTTCGGCTGGCAGATGCGCTTCCGCCTGCAGGACGGTTTTCCGCTCCTGACCACCAAGAAGCTGCACACGCGCT
CGATCATCCACGAGTTGCTGTGGTTCCTGCAGGGCGACACCAACATCCGCTACCTGAGAGAAAACGGCGTGTCGATCTGG
GACGAATGGGCGGACGCCGACGGCGAGCTTGGCCCGGTGTACGGCAAGCAGTGGCGGCGCTGGGAGACCGCAGACGGGCG
CAGCGTCGACCAGATCGCACGCGTCGTCGAAAGCATCCGGCGCACCCCGGATTCGCGCCGCCATCTCGTCTCGGCATGGA
ATCCGGGCGAAGTCGACGCCATGGCCCTGCCGCCCTGCCACGCGCTGTTCCAGTTCTACGTCGCCGGTGGTCGCCTGTCA
TGCCAGCTCTACCAGCGCAGCGCGGACATCTTCCTCGGCGTGCCCTTCAACATCGCCTCCTATGCCCTGCTCACCCACAT
GGTGGCGCAGGTGTGCGAGCTCGAAGCGGGCGATTTCGTGTGGACCGGTGGCGACTGCCACCTCTACAGCAACCACCTGA
GGCAGGCGCGGGAGCAGCTCGAGCGCGCCCCGCGCCCCCTGCCGACGCTGCGCCTGAACCCCGCAGTGCGCGACCTCTTC
GGCTTCCGCTTCGAGGACATCGCGCTCGAAGGCTACGACCCGCATCCGCACATCAAGGCCCCGGTGGCGGTATGA

Protein sequence :
MRQYLDLMRHVLEHGDPKTDRTGTGTLSVFGWQMRFRLQDGFPLLTTKKLHTRSIIHELLWFLQGDTNIRYLRENGVSIW
DEWADADGELGPVYGKQWRRWETADGRSVDQIARVVESIRRTPDSRRHLVSAWNPGEVDAMALPPCHALFQFYVAGGRLS
CQLYQRSADIFLGVPFNIASYALLTHMVAQVCELEAGDFVWTGGDCHLYSNHLRQAREQLERAPRPLPTLRLNPAVRDLF
GFRFEDIALEGYDPHPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-83 63