Gene Information

Name : hemC (Tmz1t_1437)
Accession : YP_002355092.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1601991 - 1602923 bp
Length : 933 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGAGTCAAAGCAGCCCCGAGCGCATCGTCATCGCAACCCGTGAGAGCCGTCTCGCCCTGTGGCAGGCCGAGCACATCAA
GGCCCGCCTCGAGGCGCTCCACCCCGGCTGCCGGGTCGAGCTGCTCGGCATGACCACGCGTGGCGACCAGATCCTCGATC
GTCCGCTCGCGAAGGTCGGCGGCAAGGGCCTGTTCGTCAAGGAGCTCGAGACCGCGCTGCTCGACGGCCGCGCAGACATC
GCCGTGCATTCGATGAAGGACGTGCCGATGGTGATGGAGCCGGAGTTCGCGCTGCCCTGCATCACCGCGCGCGAGGTCCC
GCTCGACGCCTTCGTCTCCAGCCGCTACGAGAGCCTCGCCGACATGCCCCCGGGTGCCGTGGTCGGGACCTCCTCGCTGC
GCCGCGAGTCGCAGATCCACGCGCAGTATCCCTTCCTCGGCGTCACCAGTCTGCGTGGCAACCTCGATACCCGCCTGCGC
AAGCTCGACGAGGGTCAGTACGACGCCATCATCCTCGCCGCCGCCGGCCTCACGCGGCTCGGCCTGGGCGAGCGCATCCG
CTCGGTGATGCCGGCCGAGGTCTCGTTGCCCGCGGCCGGGCAGGGCGCGCTCGGCATCGAATGCCTTTCGGCGCGCGCGG
ACGTGATCGGCTGGCTGCAGCCGCTCGTCGATGCCGACACCACCGCGTGCGTCCTCGCCGAGCGCGCGGTCGCACGCGCG
CTCGCCGGCAGCTGCGAGGTGCCGCTGGGCGCCTACGCGGTGATGCGCGAGGGGCGGCTGTGGTTGCGCGGCTTCGTCGC
GCGCCCCGACGGCAGCACCATCGTGCGCGCCGAACGCGAGGGCGCGCCGGCCGAGGCCGAGGCGCTCGGGCGCGCGCTCG
CCGACGACCTGCGGGCGCAGGGCGCGGAAGCGATCCTCGCCGAGCTCGGCTGA

Protein sequence :
MSQSSPERIVIATRESRLALWQAEHIKARLEALHPGCRVELLGMTTRGDQILDRPLAKVGGKGLFVKELETALLDGRADI
AVHSMKDVPMVMEPEFALPCITAREVPLDAFVSSRYESLADMPPGAVVGTSSLRRESQIHAQYPFLGVTSLRGNLDTRLR
KLDEGQYDAIILAAAGLTRLGLGERIRSVMPAEVSLPAAGQGALGIECLSARADVIGWLQPLVDADTTACVLAERAVARA
LAGSCEVPLGAYAVMREGRLWLRGFVARPDGSTIVRAEREGAPAEAEALGRALADDLRAQGAEAILAELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-60 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-60 61