Gene Information

Name : Tmz1t_1116 (Tmz1t_1116)
Accession : YP_002354771.1
Strain : Thauera sp. MZ1T
Genome accession: NC_011662
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1220586 - 1221863 bp
Length : 1278 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bbr:BB0876 polysaccharide biosynthesis protein

DNA sequence :
ATGCACACCCTCGACACCCTCAAGCTCGCCATCATCGGCCTCGGTTACGTCGGCCTGCCGCTCGCGGTCGAATTCGCCAA
GAAGCGCTCCGTCGTCGGCTTCGACATCAACCAGGCCCGCATCGACGCCCTCAAGACCGGCCACGACGCCACCCTCGAGG
TCTCCGACGAAGAACTGCGCGAAGCCACCGGCCTGCAATACAGCGCCAACCTGCAGGACCTCGCCGCCTGCAACACCTTC
ATCGTCACCGTCCCCACCCCCATCGACGAGCACAAGCAGCCCGACCTCACCCCGCTGGTCAAGGCCAGCGAGACCATCGG
CAAGGTGCTCAAGAAGGGCGACATCGTCATCTACGAATCCACGGTCTACCCCGGCGCCACTGAGGAAGACTGCGTCCCGG
TGCTGGAGAAGTTTTCCGGCCTCAAATTCAACGTCGACTTCTACGCCGGCTACAGCCCCGAGCGCATCAACCCGGGCGAC
AAGGAACACCGCGTCTCCACCATCAAGAAGGTCACCTCCGGCTCCACCCCCGAAGTGGCCGAGCTGGTCGACCAGCTCTA
CCGCCAGATCATCGTCGTCGGCACCCACAAGGCCGAAAGCATCAAGGTGGCCGAAGCCGCCAAGGTCATCGAGAACACCC
AGCGCGACGTCAACATCGCCCTCATCAACGAGCTGGCCATCATCTTCAACAAGATGGGCATCGACACCGAGGCCGTGCTG
CAGGCCGCCGGCAGCAAGTGGAACTTCCTGCCCTTCCGTCCGGGCCTGGTCGGCGGCCACTGCATCGGCGTGGACCCCTA
CTACCTCACCCACAAGGCGCAGTCCATCGGCTACCACCCCGAGATCATCCTCGCCGGCCGCCGCCTCAACGACGGCATGG
GCGCCTACGTGGTGTCGCAGCTCGTCAAGGCCATGCTCAAGCGCCGCATCACCGTCGAAGGCGCGCGCGTGCTGGTCATG
GGCCTCACCTTCAAGGAAAACTGCCCGGACCTGCGCAACACCCGCATCGTCGACATCGTCAAGGAACTCGGCGAGTACAA
CATCCAGGCCGACGTGTACGACCCGTGGGTGGACGTGGCCGAGGCCCAGCACGAATACGGGCTCACTCCGATCGACAAGC
CGGAGCCCGGCGCCTACGACGCGATCATCGTCGGCGTGGCGCATCAGCAGTTCAAGGACATGGGAGCCGAGGCCATCCGC
GCGCTCGGCAAGCCGGAACATGTGGTGTATGACCTCAAGTATGTGATGCCGAGGAATGCGGCGGATCTGCGACTTTAA

Protein sequence :
MHTLDTLKLAIIGLGYVGLPLAVEFAKKRSVVGFDINQARIDALKTGHDATLEVSDEELREATGLQYSANLQDLAACNTF
IVTVPTPIDEHKQPDLTPLVKASETIGKVLKKGDIVIYESTVYPGATEEDCVPVLEKFSGLKFNVDFYAGYSPERINPGD
KEHRVSTIKKVTSGSTPEVAELVDQLYRQIIVVGTHKAESIKVAEAAKVIENTQRDVNIALINELAIIFNKMGIDTEAVL
QAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSIGYHPEIILAGRRLNDGMGAYVVSQLVKAMLKRRITVEGARVLVM
GLTFKENCPDLRNTRIVDIVKELGEYNIQADVYDPWVDVAEAQHEYGLTPIDKPEPGAYDAIIVGVAHQQFKDMGAEAIR
ALGKPEHVVYDLKYVMPRNAADLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-149 69
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-149 69
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-114 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmz1t_1116 YP_002354771.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-149 69