Gene Information

Name : thyA (LMHCC_0682)
Accession : YP_002349651.1
Strain : Listeria monocytogenes HCC23
Genome accession: NC_011660
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 694113 - 695057 bp
Length : 945 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATATTTGGATTTAGAAAAGTACGTTTTAGAGAATGGAACACAAAAAGGAGATCGCACTGGAACTGGAACAAT
CAGCACATTTGGTTATCAAATGCGTTTTGATTTACAAGAGGGCTTTCCGATTATGACAACAAAACGGGTACCATTTAAAC
TTGTAGTAAGTGAACTGCTATGGTTTTTACATGGAGATACGAATATTCGCTACCTTTTACAGCATAATAATAATATTTGG
AATGAATGGGCTTTTGAGCGTTTTGTGAAAAGCGATGATTATAAAGGCGAAGATATGACTGACTTTGGTCTGCGTGCTGA
ACGTGATCCAGCTTTCAAAGAAGTGTATCAAGCGGAGATGGAGAAGTTTAAAACACGTATTTTAGAAGACGAAGCGTTCG
CGAATAAATACGGTGAGCTAGGTAATATTTACGGTAAACAATGGCGCGAATGGAAGACTTCACAAGGAGAAACAATTGAT
CAGTTAGCGGATTTGATTGAAATGATTAAAACGAATCCGAACTCGCGTCGTTTGATTGTGTCTGCTTGGAATCCAGAAGA
TATTCCGAATATGGCTTTACCGCCATGTCATTCGCTATTCCAATTTTATGTAGCGGACGGAAAATTATCATGTCAGCTGT
ATCAACGTAGTGCCGATATTTTCCTTGGTGTGCCGTTTAATATTGCGAGCTATGCACTTCTAACACACCTGATTGCGCGT
GAAGTAGGGCTGGAAGTTGGCGAGTTTATCCATACAATGGGTGACGCGCATCTTTATAACAACCATATTGAGCAAGTGAA
AGAACAGTTGTCTAGAACACCGCACAAACTTCCAAAATTAGTGCTTTCAGATAAACCAGCAACGATTTTTGATTTTGATG
TAGCGGATATTTCACTGGATGGTTATAATCCAGATCCAGCAATTAAAGCACCAATTTCAGTATAA

Protein sequence :
MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIW
NEWAFERFVKSDDYKGEDMTDFGLRAERDPAFKEVYQAEMEKFKTRILEDEAFANKYGELGNIYGKQWREWKTSQGETID
QLADLIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAR
EVGLEVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHKLPKLVLSDKPATIFDFDVADISLDGYNPDPAIKAPISV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-101 65