Gene Information

Name : lysS (LMHCC_2414)
Accession : YP_002351363.1
Strain : Listeria monocytogenes HCC23
Genome accession: NC_011660
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2397916 - 2399412 bp
Length : 1497 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGTAACGAGAATCATGAAGAACTAAATGACCAACTCATCGTCCGTCGCGAAAAAGTGGACATATTACGCGAAGAAGG
CATAGATCCTTTTGGCGAAAAATTCATCCGTTCCATCAGCCCGGAAGAAATTGAAACAAAATTCGCTGATAAATCAAAAG
AAGAACTTGAAGAAGATGCTATTGAAGTTTCTGTAGCAGGCCGTATTATGACAAAGCGTGTAAAAGGTAAAGTAGGTTTC
ACGCATATTCAAGACCGTTTCCATCAATTACAAATCTATATCCGCAAAGATGCGATTGGCGAAGATGCATATGCAGTTTT
CAAATTAGCAGATTTAGGCGACATTATTGGTATAAAAGGAACTATTTTCCGTACCAATACAGGTGAGCTTTCTGTTAAAG
CAACAGAGTTCACGCTATTATCTAAATCACTGCGTCCGCTTCCTGATAAATACCATGGCTTAAAAGACGTAGAACAACGC
TACCGTCAACGCTACTTAGATTTAATCACAAACGAAGAAAGTCAAAACCGCTTCGTAATGCGTAGTAAAATTTTGAAATA
CACACGTGACTATATGGATAGCCAAGGTTTCTTGGAAGTTGAAACACCAGTACTTCACACGATTGCAGGTGGGGCCGCTG
CGAAACCGTTCATTACACACCATAACGCACTTGATATGGAACTTTACTTACGAATTGCATTAGAACTTCATCTGAAACGC
CTGATTGTCGGTGGGATGGATAAAGTATATGAAATAGGCCGTGTTTTCCGTAATGAAGGAACATCCACACGACACAACCC
AGAATTTACAATGCTAGAATCCTATGCAGCATATGAAGATTACGAAGATGTTATGAACCTAGTAGAAGGTTTAGTATCTA
CAGTATGTAAACAAGTAAATGGAACAACAGAAATAACATACGGCGAATACAAAGTAGATTTAACTCCGAACTGGCGCCGC
ATCCACATGGCAGATGCTGTAAAAGAATATGTAGGCGTGGATTTCTGGAACGTAACTTCCGATGAGGAAGCGCGCGAACT
TGCTAAAAAACACGATGTACCTGTAACAGAACACATGACATACGGACACATCTTAAATGAGTTTTTTGAAACACACGTAG
AAGAAAAACTTATTCAACCAACATTTGTTTACGGACACCCAGTAGAGATTTCTCCATTGGCGAAGAAAAACAAAGAAGAT
GAACGTTTCACCGACCGCTTTGAGTTATTTATCGTTGGTCGCGAACATGCAAATGCATTTTCAGAATTAAACGATCCTAT
CGATCAAAGAGAACGTTTTGAAGCACAAATGAAAGAACGTGAACAAGGGAATGATGAAGCGCACGGAATGGATGCTGACT
TCCTTGAAGCATTAGAATATGGTTTGCCGCCAACTGGTGGACTTGGAATAGGTGTAGATCGCTTGGTAATGCTATTAACA
AATGCTCCATCTATTCGAGATATTCTGCTATTCCCAACTATGAAACACCGCGATTAA

Protein sequence :
MSNENHEELNDQLIVRREKVDILREEGIDPFGEKFIRSISPEEIETKFADKSKEELEEDAIEVSVAGRIMTKRVKGKVGF
THIQDRFHQLQIYIRKDAIGEDAYAVFKLADLGDIIGIKGTIFRTNTGELSVKATEFTLLSKSLRPLPDKYHGLKDVEQR
YRQRYLDLITNEESQNRFVMRSKILKYTRDYMDSQGFLEVETPVLHTIAGGAAAKPFITHHNALDMELYLRIALELHLKR
LIVGGMDKVYEIGRVFRNEGTSTRHNPEFTMLESYAAYEDYEDVMNLVEGLVSTVCKQVNGTTEITYGEYKVDLTPNWRR
IHMADAVKEYVGVDFWNVTSDEEARELAKKHDVPVTEHMTYGHILNEFFETHVEEKLIQPTFVYGHPVEISPLAKKNKED
ERFTDRFELFIVGREHANAFSELNDPIDQRERFEAQMKEREQGNDEAHGMDADFLEALEYGLPPTGGLGIGVDRLVMLLT
NAPSIRDILLFPTMKHRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-113 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002351363.1 lysyl-tRNA synthetase VFG1668 Protein 5e-113 48