Gene Information

Name : LMHCC_1625 (LMHCC_1625)
Accession : YP_002350581.1
Strain : Listeria monocytogenes HCC23
Genome accession: NC_011660
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1627768 - 1629942 bp
Length : 2175 bp
Strand : +
Note : -

DNA sequence :
ATGAACTGTGAAAAATGTAATCAAAATCCAGCAACAATCCAACTATATATGAATATTAATGGCAAGCGTGTAGAAATGCC
GCTTTGTGCCTCTTGTTATGCAGAAGTTAGAAATCAAGCCAACTTTGGCGCAAATGAGTTTCCGGGAGCAAGCGGTTCTC
CGTTTGACGATATTTTCCGTCAATTGAGTGGTGCTGCTAGTCAAGCAAACCGTGAACAAAGAAGCCAAGCAAACGCACAA
GTACAAACACAAACTGCTGGTGGCGGCAATGGTTTACTAGATGAATTTGGAACAAACTTAACAGATATGGCGAAAAATGA
GCAACTCGACCCTGTCATCGGTCGTGACAAAGAAATTAAACGCGTCATTGAAATATTAAACCGCCGTAATAAAAATAATC
CAGTCTTAATTGGTGAACCAGGTGTTGGTAAAACAGCTGTCGTCGAAGGACTTGCAAATGCGATTGTCGCAGGAGAAGTT
CCAAGCAAATTAATGAACAAAGAAGTTATCTTATTAGATGTCGCTTCACTTGTTTCTGGAACAGGGATCCGTGGTCAATT
TGAAGAACGCATGAAACAACTAATTAAAGAGCTACAAGAACGTAAAAACACGATTCTATTTATTGATGAAGTGCATACGA
TTGTTGGGGCAGGTTCCGCAGAAGGCTCGATGGATGCAGGAAACATTCTAAAACCAGCTCTAGCTCGTGGCGATTTACAA
ATGATTGGCGCTACTACGCTAAAAGAGTACCGCACAATCGAAAAAGACGCCGCACTTGAGCGTCGTTTCCAACCAGTAAC
TGTAAGCGAACCATCCACAAAAGAAACGCTAACTATTTTAAATGGTTTAAAACCAAAATACGAAGATTTCCATGAAGTAG
TTTATTCACCAGAAGCATTATCAGCTGCAGTTGAATTAAGCGCTCGTTACATCCAAGATCGTCATTTGCCAGACAAAGCG
ATTGATTTAATGGATGAAGTTGGTTCCAAATACAATCTATCTATTGAAAAATTGGACGAAAATACCGTGAGCGAACGTGT
TGCCCGTTTAGAAGAGGAAAAAAATCAAGCTCTTCAAATGGAAGACTACGAAAAGGCAGCTAAAGTTCGTGACGAGATTA
CTCGCTTAGAAGAAAATAAAACAAGCAATTCCTTCTCAGAACGCCCAGTCATCCAAGCATCTGATATCCAAGCGATTATT
GAAGAAAAAACTGGCATCCCAGTAGGACGTTTACAAGAAGACGAGCAATCCAAAATGAAGAACTTAGAAAGCAACTTAAC
TGGTAAAGTTATTGGTCAAGAAGATGCTGTAAGAAAAGTAGCCAAAGCAATTCGTCGTAGTCGTGTTGGACTTAAATCAA
AAAATCGCCCAATTGGTTCCTTCCTATTTGTTGGACCAACTGGTGTCGGAAAAACAGAACTTGGACGCACGCTAGCTCGT
GAATTATTCGGTACTAGTGAAGCGATGATTCGTTTAGACATGAGTGAATTCATGGAAAAACACAGCGTCTCTAAATTAAT
CGGTTCCCCTCCTGGCTATGTTGGTCACGAAGAAGCTGGACAATTAACAGAAAAAGTTCGTCGCAATCCGTATAGCATCA
TTTTGTTAGACGAAATCGAAAAAGCACATCCAGACGTTCAACATATGTTCCTGCAAATTTTAGAAGACGGTCGACTAACT
GATTCACAAGGACGTACAGTGAGCTTTAAAGATACAGTCATCATTATGACAAGTAACGCTGGCGCAACTGACACAGAAGC
TTCTGTCGGCTTTAATACAACAACCGAATCAAAACTTGAAAAAGGTTCTGACATCTTAGCAAAATTAGGTGCATACTTCA
AGCCAGAATTCTTAAACCGTCTAGACAGCGTCATTGAATTTAAATCCCTAGAAAAAGACGATTTAGTACAAATCATCGAC
TTAATGCTCGTTGATTTAAATGAAATGCTCGCTCAAGAAGATGTGACAATCGATGTTTCTAAAGAAGTAAAAGAACATTT
GATTGACCTTGGTTATGACCCTAAATTCGGAGCACGTCCACTACGCCGGACTATCCAAGAACACCTAGAAGATGCCATTG
CCGACAGTTTAATTGAACAACCAGAAGCAAAACATCTCGTTGCAACCCTTAACGATAATAAAGAAATTACTATAACAGAA
CAAGTAACAGTGTAA

Protein sequence :
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFRQLSGAASQANREQRSQANAQ
VQTQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRVIEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGEV
PSKLMNKEVILLDVASLVSGTGIRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQ
MIGATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALSAAVELSARYIQDRHLPDKA
IDLMDEVGSKYNLSIEKLDENTVSERVARLEEEKNQALQMEDYEKAAKVRDEITRLEENKTSNSFSERPVIQASDIQAII
EEKTGIPVGRLQEDEQSKMKNLESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAR
ELFGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLT
DSQGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTESKLEKGSDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIID
LMLVDLNEMLAQEDVTIDVSKEVKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNDNKEITITE
QVTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-156 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LMHCC_1625 YP_002350581.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 0.0 99
LMHCC_1625 YP_002350581.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 3e-160 53