Gene Information

Name : guaA (LMHCC_1537)
Accession : YP_002350495.1
Strain : Listeria monocytogenes HCC23
Genome accession: NC_011660
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1542275 - 1543819 bp
Length : 1545 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAGACTTTACCGAGCAAGAGAAAATTATCGTTCTAGATTTTGGTAGTCAGTACAATCAACTAATTACGCGCCGCAT
TCGTGAATTCGGTGTGTATAGTGAATTACATCCGCATACTATTACAGTTGAAGAAATGAAAGCACTAAATCCAACGGGGA
TTATTTTTTCAGGAGGACCTAACAGTGTGTATGACGAAGATGCCTTCCGCGCTGACGAAAGAATCTTTGACATGGGAATT
CCGATTTTAGGAATTTGTTACGGCATGCAATTAATGACAACGCACTTCGGTGGCAAAGTAGAACGTGCGAAAGACCGCGA
ATACGGGAAAGCGGACATTCACGTCGAAAAACCAAGTCGTTTATTTGCTGGACTACCAACCGATCAAGTTGTTTGGATGA
GTCACGGCGATTTAGTTGTCGAGGAACCAGCTGGATTTGAAGTAACAGCTACTAGTAAGTCTTGCCCAATTGCAGCTATT
GCAGACGAAGAGCGTTCTCTTTACGGCGTGCAATTCCACCCAGAAGTACGTCACTCAGTTCACGGAAACGAATTACTGAA
GAATTTTGCATTAAACGTTTGTGGCTGTAAAGGCGACTGGACAATGGAGAACTTTAGTGAAGTAGAAATCGCTAAAATCC
AAGAAATCGTAGGCGACAAAAAAGTCTTGCTTGCACTTTCTGGCGGCGTAGATTCCTCTGTTGTTGGTGTGTTAATTCAT
AAAGCAATTGGCGACCAACTAACATGTATTTTCGTTGATCATGGCCTTCTTCGTAAAGGGGAAGCTGACCAAGTAATGGC
GACATTACAAGGCGAGTTCAACATGAACATCATCAAAGTAGATGCGAAAAAACGCTTCATGGACAAACTTGCTGGCGTTT
CTGACCCAGAACAAAAACGTAAAATCATCGGTAACGAATTCATTTACGTATTCGACGATGAAGCCAACAAACTAGACGGC
GTAGAATTCCTAGCACAAGGAACACTTTACACAGACATCATCGAAAGTGGTACAGCAACTGCCCAAACAATCAAGTCTCA
CCACAATGTCGGCGGTCTACCAGAAGATATGCAATTTAAACTAATCGAACCTTTAAATACACTTTTCAAAGATGAAGTTC
GCGCACTAGGAACAGAACTTGGCATGCCTGACGCAATCGTTTGGCGCCAACCATTCCCAGGCCCAGGCTTAGGAATCCGC
GTTCTTGGCGAAATTACGGAAGAGAAATTAGAGATTGTCCGCGATTCTGATTACATCTTGCGTGAAGAAATCAAAAACGC
AGGTCTAGAACGCGAAATTTGGCAATACTTTACTGCTCTTCCAAATATCCGTAGCGTTGGTGTTATGGGTGATGGTAGAA
CGTATGACCATACTGTAGTTGTTCGTGCGGTGACAAGTATTGATGGTATGACAGCCGATTGGGCACGTATTCCGTGGGAT
GTACTGGAGAAAATTTCGGTACGGATTGTGAATGAAGTGGATCATGTGAATCGTGTTGTTTATGATATTACGAGTAAGCC
ACCAGCTACGGTTGAGTGGGAGTAA

Protein sequence :
MKDFTEQEKIIVLDFGSQYNQLITRRIREFGVYSELHPHTITVEEMKALNPTGIIFSGGPNSVYDEDAFRADERIFDMGI
PILGICYGMQLMTTHFGGKVERAKDREYGKADIHVEKPSRLFAGLPTDQVVWMSHGDLVVEEPAGFEVTATSKSCPIAAI
ADEERSLYGVQFHPEVRHSVHGNELLKNFALNVCGCKGDWTMENFSEVEIAKIQEIVGDKKVLLALSGGVDSSVVGVLIH
KAIGDQLTCIFVDHGLLRKGEADQVMATLQGEFNMNIIKVDAKKRFMDKLAGVSDPEQKRKIIGNEFIYVFDDEANKLDG
VEFLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPGPGLGIR
VLGEITEEKLEIVRDSDYILREEIKNAGLEREIWQYFTALPNIRSVGVMGDGRTYDHTVVVRAVTSIDGMTADWARIPWD
VLEKISVRIVNEVDHVNRVVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 76
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 76
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-130 53