Gene Information

Name : pyk (LMHCC_0999)
Accession : YP_002349961.1
Strain : Listeria monocytogenes HCC23
Genome accession: NC_011660
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1030751 - 1032508 bp
Length : 1758 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAAAAACGAAAATTGTTTGTACAATTGGTCCTGCAAGTGAGTCAGTTGACACTTTAGTTCAGTTGATCGAAGCAGG
AATGAACGTAGCACGTCTTAATTTCTCTCACGGAGACTTTGAAGAGCACGGTGCGCGTATTGTAAATATCCGTGAAGCAT
CGAAAAAAACTGGCAAACAAGTGGCTATCTTACTTGATACAAAAGGTCCAGAAATCCGTACGAACGACATGGTTGGCGGA
AAACTAGAATTCCAAACAGGTGATGTTGTACGTGTTTCTATGACTCCTGTTGAAGGAACAAAAGAAAAATTCTCCGTAAC
TTACGGCGAACTTTACGATGACGTAGAAATCGGTTCTTCCATTTTACTTGATGACGGTTTAATCGGTCTTGAAGTAATCG
AAAAAGACGAAGCTAATCGCGAACTAGTAACAAAAGTACTTAACCCAGGTGTACTTAAAAATAAAAAAGGTGTTAACGTA
CCAAACGTTTCTATCAACCTACCAGGAATCACAGAAAAAGACGCTGCTGATATCCGCTTCGGTTTAGAACAAGGTATCGA
TTTTATCGCTGCATCTTTCGTACGTCGTGCTACAGATGTTCTTGAAATTACTAAAATTCTAGAAGAGCATAATGCAACTC
ACGTACAAATTATTCCTAAAATCGAAAACCAAGAGGGCGTTGACAATATCGACGAAATCTTACAAGTATCTCAAGGCTTA
ATGGTTGCTCGTGGTGACCTTGGTGTTGAAATTCCAGCTGAAGAAGTTCCGATTGTACAAAAAGAACTTATCAGAAAATG
TAATAAACTTGGAAAACCTGTTATTACTGCAACACAAATGCTTGATTCCATGCAACGTAACCCACGTCCAACTCGCGCTG
AAGCAAGTGACGTAGCGAATGCGATTTTTGATGGAACAGATGCAATTATGTTATCTGGTGAAACAGCTGCTGGGGATTAT
CCAGTAGAAGCAGTTAAAATGATGGCGAAAATCGCTGTTCGTACAGAAGAAGTACTAGTTGCTCAAGATAAATTTGCACT
TAAACTTCACGAAAATACGGATATGACAGAAGCTATCGGTCAAGCAGTTGGCCATACTGCGAAAAACCTAAATGTACAAA
CTATCGTTGCTGCGACTCAAAGTGGTCACACAGCGCGTATGATCTCTAAATACCGTCCAAAATCTCATATCGTTGCTGTA
ACATTCAACGAGCATGTATACCGCGGTTTAGCACTTTCATGGGGTGTTTATCCTCGTCTAGCTACTCCAGTTAGCAACAC
AGATGAAATGTTCGACCTTGCAGTGAAAGAATCTCTTGCTTCTGGCGTTGCAAAACAAGGCGACTTAATTATCATCACTG
CTGGTGTTCCAGTTACTGAAAGTGGAACAACAAACGTAATGAAAATCCAATTAATTGGTGAAAAAGTTGTTAAAGGCCAA
GGTATTGGCAGCAAATCTGTTATTGGTAAAGCAATCGTTGCTAAATCCAATGCAGAAGCACTTGAAAAAGCAGAAGAAGG
CGGAATCTTAATCGTTAAAACAACGGATAAAGAAATGCTACCTGCATTCGAGAAAAGTGCAGCAGTTGTTGTGGAAGAAG
GCGGATTAACTAGCCACGCAGCAGTTGTAGGAATCAACCTTGGCATTCCTGTCATCGTTGGCGCTAAAGATGCAACATCT
CTTGTAAAAGACGGTGAAATCATTACTGTTGATTCTCGTCAAGGCGTTGTATATAACGGTAAAACAGCAACACATTAA

Protein sequence :
MKKTKIVCTIGPASESVDTLVQLIEAGMNVARLNFSHGDFEEHGARIVNIREASKKTGKQVAILLDTKGPEIRTNDMVGG
KLEFQTGDVVRVSMTPVEGTKEKFSVTYGELYDDVEIGSSILLDDGLIGLEVIEKDEANRELVTKVLNPGVLKNKKGVNV
PNVSINLPGITEKDAADIRFGLEQGIDFIAASFVRRATDVLEITKILEEHNATHVQIIPKIENQEGVDNIDEILQVSQGL
MVARGDLGVEIPAEEVPIVQKELIRKCNKLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGDY
PVEAVKMMAKIAVRTEEVLVAQDKFALKLHENTDMTEAIGQAVGHTAKNLNVQTIVAATQSGHTARMISKYRPKSHIVAV
TFNEHVYRGLALSWGVYPRLATPVSNTDEMFDLAVKESLASGVAKQGDLIIITAGVPVTESGTTNVMKIQLIGEKVVKGQ
GIGSKSVIGKAIVAKSNAEALEKAEEGGILIVKTTDKEMLPAFEKSAAVVVEEGGLTSHAAVVGINLGIPVIVGAKDATS
LVKDGEIITVDSRQGVVYNGKTATH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-106 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002349961.1 pyruvate kinase VFG0479 Protein 1e-106 51