Gene Information

Name : sph (BCAH187_A0805)
Accession : YP_002336808.1
Strain : Bacillus cereus AH187
Genome accession: NC_011658
Putative virulence/resistance : Virulence
Product : sphingomyelin phosphodiesterase C
Function : -
COG functional category : R : General function prediction only
COG ID : COG3568
EC number : 3.1.4.12
Position : 762183 - 763184 bp
Length : 1002 bp
Strand : +
Note : identified by match to protein family HMM PF03372; match to protein family HMM TIGR03395

DNA sequence :
GTGAAAGGTAAATTGCTAAAAGGTGTACTTAGCCTTGGGATTGGTTTAGGAGTTTTATACGGAGGATCTTCAGCTCAAGC
AGATACGTCTACAGATCAAAACAACATTTTGAAAGTGATGACGCATAACGTGTACATGCTATCAACTAACTTATATCCGA
ATTGGGGACAAAGTCAGCGTGCTGATTTAATTGGGGCGGCAGATTATATTAAAAATCAAGACGTTGTTATATTAAATGAA
GTGTTTGATAATAGTGCTTCAGATCGCCTTTTAGGAAATTTGAAGAAAGAATACCCAAATCAAACAGCTGTATTAGGTCG
TAGTAACGGAAATGAATGGGATAAAACGTTAGGTAGTTATTCATCTTCAACGCCTGAAGATGGAGGCGTTGCAATCGTGA
GCAAATGGCCGATCGTTGAAAAGGTTCAATATGTATTTGCAAATGGATGCGGGCCGGATAATTTATCGAATAAAGGATTT
GTATACGCGAAGATTAAGAAAAATGATCGTTTCGTTCATGTAATTGGGACGCATTTGCAGGCAGAAGATAGTATGTGCGG
AAAAACTTCACCTGCATCTGTACGTACAAACCAGTTAAAAGAAATTCAAGATTTTATTAAAAATAAAAATATACCAAATG
ACGAGTACGTCCTATTTGGTGGTGATATGAATGTGAATAAAATAAATGCTGAGAACAATAGTGACTCAGAATACGCATCA
ATGTTCAAAACATTGCACGCTTCTATTCCATCTTATACGGGACATACAGCAACTTGGGATGCGACGACAAACAGTATTGC
AAAATATAATTTCCCTGATAGCCCTGCCGAGTATTTAGATTATATTATTGCAAGTAAAGACCATGCGAACCCGTCATTTG
TAGAGAATAAAGTGTTACAACCGAAATCTCCACAGTGGACTGTTACATCATGGCTCAAAAAATATACGTATGATGATTAT
TCTGATCATTATCCAGTAGCAGCAACTATTTCTATGAAGTAG

Protein sequence :
MKGKLLKGVLSLGIGLGVLYGGSSAQADTSTDQNNILKVMTHNVYMLSTNLYPNWGQSQRADLIGAADYIKNQDVVILNE
VFDNSASDRLLGNLKKEYPNQTAVLGRSNGNEWDKTLGSYSSSTPEDGGVAIVSKWPIVEKVQYVFANGCGPDNLSNKGF
VYAKIKKNDRFVHVIGTHLQAEDSMCGKTSPASVRTNQLKEIQDFIKNKNIPNDEYVLFGGDMNVNKINAENNSDSEYAS
MFKTLHASIPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIASKDHANPSFVENKVLQPKSPQWTVTSWLKKYTYDDY
SDHYPVAATISMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 6e-71 58
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 5e-71 58
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 7e-71 58
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 4e-77 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sph YP_002336808.1 sphingomyelin phosphodiesterase C VFG1798 Protein 4e-78 58
sph YP_002336808.1 sphingomyelin phosphodiesterase C VFG0674 Protein 2e-77 55