Gene Information

Name : hemC (BCAH187_A4600)
Accession : YP_002340526.1
Strain : Bacillus cereus AH187
Genome accession: NC_011658
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4263142 - 4264071 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCGCAAAATTATTGTAGGGTCACGAAAGAGTAAATTAGCATTAACGCAAACAAACTGGTTTATTGATCAGTTAAAAGC
GCTAGGTTTACCATATGAATTTGAAGTGAAAGAAATCGTCACAAAAGGCGATGTAATTTTAGATGTTACTCTTTCAAAAG
TAGGTGGCAAAGGCTTGTTTGTGAAAGAGATTGAACATGCGCTACTTACGAAAGAAATTGATATGGCTGTACATAGTATG
AAAGATATGCCGGCCGTACTTCCAGAAGGATTAATGATTGGTTGTACACCAAAGCGTGTTGACCCTCGTGATGCTTTTAT
CTCAAAAAACGGAGCGTCGTTTAAAGAGTTAGCAGAAGGCGCTATTTTAGGTACGAGTAGTTTAAGACGTAGTGCACAGC
TACTCGCTGCGAGACCAGACTTACAAGTGAAGTGGATTCGTGGAAATATCGATACACGTTTACGCAAATTAAAAGAAGAA
GATTACGATGCAATTATTTTAGCGACAGCGGGATTACAAAGAATGGGCTGGGATAATGAAGTTATTACAGAACATTTAGA
TGAGACGTTATGTGTACCTGCTGTAGGACAAGGTGCATTAGCGATTGAGTGTCGTGAGGATGATAAAGATTTACTGCAGT
TGTTAGCTCATATGAATGATGGAGTAACAGAAAAAACAGTGGCAGCAGAACGCGTATTTCTTCATAAACTTGAAGGGGGA
TGCCAAGTTCCGATCGCTGGATATGCAACTCTTACGGAAAACGATGCAATCGAATTAACAGCTCTTGTCGGGTCTATGGA
CGGTTCTGTTTTATTGAAAGAGAAAGTAGTAGGAACTGATCCAGAGAAAGTAGGATTAGAGGCTGCGGACCGTTTAATTA
ACCAAGGCGCAAAAGAACTCATTCTTGCTGCAAATAAGGAGCAACAATAA

Protein sequence : 
MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSM
KDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEE
DYDAIILATAGLQRMGWDNEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHMNDGVTEKTVAAERVFLHKLEGG
CQVPIAGYATLTENDAIELTALVGSMDGSVLLKEKVVGTDPEKVGLEAADRLINQGAKELILAANKEQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-58 48
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-58 48