Gene Information

Name : clpB (BCAH187_A1327)
Accession : YP_002337297.1
Strain : Bacillus cereus AH187
Genome accession: NC_011658
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1245188 - 1247788 bp
Length : 2601 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCTCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAACAAGGTGCTGAAGGTTTAATTAAGAAAAAGCCCTCTGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCTTTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAAAAATTGCAAGATGA
TTACATTTCAGTTGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGCGATATAAACCAATTATTTACAAGATTTCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTAAGAGCGGGGAAAATTGACCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCAGTTTTAATTGGTGAACCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGGTTAGCACAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTAAAAGATAGAACAATT
TTTGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGCGGTGAGTTTGAGGAGCGTCTCCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGTATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGTAAAACAGAAG
GCGCAATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACGACGTTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCGGACCGTTTCTTACCAGATAAAGCAATTGATCTTGTCGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAAAAGGACTTTGGTAGCCAAGAACGTCTAAAAACGTTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCCAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGATTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCGCGCGCAGGTATCAAAGACCCGAACCGTCCGATTGGTTCCTTCATTTTCTTAGGACCTACTG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCATTATTCGATAGTGAAGAACAAATGATTCGTATTGATATG
TCTGAGTATATGGAGAAACACGCGGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCGGTTATTTTATTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGACGGTCGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGATGATGGCTCCATTAAAGAGGAATCAAGAGA
GCTTGTAATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCACATTACG
GTAGAATTAACAGACGCAGCGAAAGAGTTTGTTGTCGAAGCTGGCTTCGATCCGATGTACGGAGCCCGTCCATTAAAAAG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACGATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAGTAA

Protein sequence :
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAEGLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEDDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002337297.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG0079 Protein 0.0 48
clpB YP_002337297.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 4e-110 41