Gene Information

Name : BCAH187_A0111 (BCAH187_A0111)
Accession : YP_002336200.1
Strain : Bacillus cereus AH187
Genome accession: NC_011658
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 95450 - 97885 bp
Length : 2436 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCGATTCGTATTGGGCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTTG
GATTAAGCCCGGAGAAAGTTCAAAAAGAAGTAGAAGCGTTAATTGGACGCGGAACAGAAGCTTCTCAAACCGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGCTGTCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTCTACTTGGTTTAATCCGCGAGGGTGAAGGGGTAGCAGCACGTGTTTTAAATAACTTAGGTGTTAGCTTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCATCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACGAAAAACAATCCTGTATTAATTGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCAGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCCGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATCCGCCAAGCAGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAACATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAGTGTATTGGAGCGACAACGTTAGATGAA
TACCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGTGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAGCAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACGTGGACTCGTATCCCGGTTTCTAAGCTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCGATTCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGTCGTGCTAGAGCAGGCTTGAAAG
ATCCGAAACGTCCGATTGGTTCATTTATTTTCTTAGGACCAACAGGTGTAGGTAAAACGGAGCTAGCAAGAGCGTTGGCA
GAATCTATGTTCGGTGATGAGGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGATCTCCTCCAGGATATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCTTATTAGATGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCTAAAGGGCGTACAGTTGATTTCCGTAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAAGCGTTAAA
ACGTAATAAACATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCAGATATGAAAGGTAAAGTAATGGATGAAC
TGAAAAAGGCATTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACAGAAGG
AGCGATTTCGGCTATTGCTGATAAAGGGTTTGACCGAGAGTACGGTGCTCGTCCGCTTCGTAGAGCAATTCAGAAACATG
TAGAAGATAGACTATCGGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCAH187_A0111 YP_002336200.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 77
BCAH187_A0111 YP_002336200.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 5e-148 52