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Name : leuS (THA_491) Accession : YP_002334323.1 Strain : Thermosipho africanus TCF52B Genome accession: NC_011653 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 487369 - 489846 bp Length : 2478 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGAAAGAATATATTCCAGGTCAGATAGAAAAAAAGTGGCAAAAAGTATGGGAAGAGGAAAAAGTATTTGAAACACCACA ATATTCTGAGAAACCAAAATTTTATGATCTAGTAATGTTTCCATACCCTTCAGGGACATTACATGTTGGCCACGTGAAAA ATTACGTTATTGGAGATATAGTTGCAAGGTATAAAAGAATGAAAGGTTTTAATGTTTTACATCCATTTGGTTACGATGCA TTTGGCCTTCCTGCTGAAAATGCTGCTATTAAAAATAAAATTCATCCTGAGGTTTGGACTTTTAAAAATATAGAAACAAT TAGAAACCAAATTAAAAAGATAGGAATAAGTTATGATTGGAAAAGGGAAATTGCAACATGTACAGAAGATTATTACAAAT GGACTCAATGGTTATTTGTCAAAATGTATGAAAAAGGACTTGCATATAAGAAGAAAGCAGCTGTTAATTGGTGCCCAAGC TGTCAAACAGTACTTGCAAATGAGCAAGTTGTAGATGGCAAGTGTGAAAGGTGTGGTACAGAGGTTACTTTAAAACATCT TGAGCAATGGTATTTTAAGATAACTGATTATGCTGAAAGACTTTTAAATGATTTAGAAAGGCTAGAAGGTTGGCCTGAGA ATGTAAAAACAATGCAAAAAAATTGGATTGGAAAAAGCACAGGTGCAGAAATTGATTTTAAAGTTGATGGCCTTGATATG AGCATTAGAGTATTTACTACAAGGCCTGATACAATCTGGGGAGTAACCTTTATGGCTATTGCTCCAGAGTCACCTCTTGT TGAAACGCTTGTAACTGAAGATAAAAAGGAAGAACTAGAAGAATTTTTGAAAAAGGTTTCTTTGGAAGATAGGTTTAAAC GAACAAGCTTGGAAGCCGAAAAGGAAGGCTTTTTCTTGGGAAGATATGCTATAAATCCTGTCACTGGAGAAAAAATTCCT ATTTACGTTGCTAATTATATATTATACGAATATGGAACAGGTGCAATTATGGCAGTGCCTGCACACGATCAAAGAGACTT TGATTTTGCAAAAAAATACAATATACCAATAAGACTTGTTATTGATAATCCTGAAAGCCCAATAGATGTAGAAAAAATGG AAAAAGCATACGAAGATGAAGGTATAATGGTAAATTCTGGACCATTTAATGGTATTTCAAGCAAAGAAGCAATTGAAAAA ATAATAGATTATCTTGAGGAAAAGAATATTGGGAAAAGAAGTGTTCAATATAAATTGAGAGATTGGCTTATCTCAAGACA AAGATATTGGGGAGCCCCTATTCCAGTTGTTTATTGTGAAAAATGTGGTACGGTAGCTGTTCCGGAAGAACAACTTCCAG TGAAACTTCCAAAAGATGTTGAATTCTTACCAACTGGACAATCACCACTTTCATTGGATGAACAATTTTTGAATACAACA TGTCCAAAGTGTGGTGGCCCTGCAAGGCGAGAAGCTGATACGATGGATACGTTTGTGGATAGTTCATGGTATTATCTAAG ATATGTAAATCCAAATCTTGAAGATAAACCATTTGAAAGTAAAGATGTTAACTATTGGCTTCCAGTTGATCAATACATAG GTGGTGTGGAACACGCGGTTTTGCACCTTTTATATTCAAGATTTATAACCAAAGTCTTGCATGATATGGGATATGTTGAT TTTGATGAGCCATTTACGAACCTATTTACACAAGGAATGATTTACAAAGATGGATGGAAAATGAGTAAATCTAAAGGAAA TGTAGTGTCACCAGATGATATGATTGAAAAATATGGTGCAGATACACTCAGAACATACATATTATTTATGGCCCCACCGG AAAAAGATGCAGAATGGAGCGATGCAGGAATAGAAGGTGTCCATAGATTTTTAAAGAGACTTTGGAATAATATTTATTCT GTGCTTGAAAAAATTAAAAATGTTAGTGCAGAAAAAATAGAATTAAAAAATAAGTTAGAAAAGGATTTAAGAAGGAAATT ACATCAGTCGATTAAAAAAATAACAGAAGATATAGAAGGTGGATTTAAATTCAATACTGCAATTGCAGGATTAATGGAAT TAAACAACAGTTTTTCAGATTATTTGAATAAGACTGAAGAAAAAGATTTAAATTTACCTCTTTTGAGGGAATTGGTTGAA AAGCTTGCACTTATACTTTCGCCGTTTGCACCACATATGGCTGAGGAAATTTGGCATGACTTAGGCAATGATACATTAAT TGTAAATGAAGAATGGCCAAAGTATGATGAAAAGGCTTTGGAAGTTGATGAAGTAACTGTAATAATACAGATAAATGGTA AAGTTAGGGGAAAAATAAATGTTGATGTCAATGCAGATGAAGAGACAGTGAAAAAGATTGCTTTTGAAGAGCCTAAGGTA TCTTCGTATATAGAAGGAAAAGAAATAGTAAAGGTTATTTATGTAAAGAATAAGCTGCTTAATATCGTTGTAAAATGA Protein sequence : MKEYIPGQIEKKWQKVWEEEKVFETPQYSEKPKFYDLVMFPYPSGTLHVGHVKNYVIGDIVARYKRMKGFNVLHPFGYDA FGLPAENAAIKNKIHPEVWTFKNIETIRNQIKKIGISYDWKREIATCTEDYYKWTQWLFVKMYEKGLAYKKKAAVNWCPS CQTVLANEQVVDGKCERCGTEVTLKHLEQWYFKITDYAERLLNDLERLEGWPENVKTMQKNWIGKSTGAEIDFKVDGLDM SIRVFTTRPDTIWGVTFMAIAPESPLVETLVTEDKKEELEEFLKKVSLEDRFKRTSLEAEKEGFFLGRYAINPVTGEKIP IYVANYILYEYGTGAIMAVPAHDQRDFDFAKKYNIPIRLVIDNPESPIDVEKMEKAYEDEGIMVNSGPFNGISSKEAIEK IIDYLEEKNIGKRSVQYKLRDWLISRQRYWGAPIPVVYCEKCGTVAVPEEQLPVKLPKDVEFLPTGQSPLSLDEQFLNTT CPKCGGPARREADTMDTFVDSSWYYLRYVNPNLEDKPFESKDVNYWLPVDQYIGGVEHAVLHLLYSRFITKVLHDMGYVD FDEPFTNLFTQGMIYKDGWKMSKSKGNVVSPDDMIEKYGADTLRTYILFMAPPEKDAEWSDAGIEGVHRFLKRLWNNIYS VLEKIKNVSAEKIELKNKLEKDLRRKLHQSIKKITEDIEGGFKFNTAIAGLMELNNSFSDYLNKTEEKDLNLPLLRELVE KLALILSPFAPHMAEEIWHDLGNDTLIVNEEWPKYDEKALEVDEVTVIIQINGKVRGKINVDVNADEETVKKIAFEEPKV SSYIEGKEIVKVIYVKNKLLNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-160 | 45 |
