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Name : lysS (THA_1523) Accession : YP_002335305.1 Strain : Thermosipho africanus TCF52B Genome accession: NC_011653 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 1528779 - 1530287 bp Length : 1509 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : TTGTTAAAGGAGTTTAGGGAACAGAGGATAAATGAAATTAAGCAGATAAGTGCAAAAGGTGTTAATCCATATCCATACAA ATTTGAAAAAACACATAGTAGCCAGGATATAAAAGCTCAATTTGAGAACTTAAACCCTGGAGAAGTTAAAGAAGATGCAA GTGTGTCTACTGCTGGAAGAATAATGTCTTTAAGGCATCATGGTAAAAGTGCATTTTTCCATATTAAAGATTTCTTTGGT AGAATTCAGGCATATATTAGGCAAGATATAGTTGGAAAAGATGTATACGAATTTTTTAAAGAACATATTGCAATTGGAGA TATAGTTGGTGTAAAGGGAAGTGTCTTTAAAAGTAAAACTGGAGAAGTGACAATTTTGGTAAAAGAAATTGAGCTTCTTA ATAAGCCTTTAAGGCCGATGCCAGAAAAATGGCATGGAATTAAAGATAAGGAAGTTTTGTATAGACAAAGATATGTTGAT ATGATTGCTAACGATGAAACACTAAATAGATTTAGAATAAGATTTGAGATAATAAAGCTTATTAGAGAATTTTTGAATTC AAAAGGATTCATTGAGGTTGAAACACCAATATTAGAATATGTTACGGGAGGAGCGTCAGCAAGACCATTTATAACACACT TGAATGTGTTTGATATTGATATGTACATGAGAATTGCTACAGAACTTTATTTGAAGAGATTCATAGTGGGTGGATTTGAA AAAGTATATGAATTAGGAAAAAATTTTAGAAATGAAGGTCTTTCTTACAAGCATCACCCTGAATTTACTTCAATTGAAAT TTATCAGGCATATGCCGACTATGAAGATATGATGAACTTAACTGAAGAACTTTTTGTGTTTATTGTTGAAAAACTTTTTG GAACAACAAAAGTCAAATATCAAGATATAGAAATTGATTTTTCAAGGCCATGGAGAAGAGTTAAAATGAGAGATTTTATT AAAGAACATTTAGGTGTTGATATCCTTGAAGATACAGAAGAAAAGATGTTAGAAGTATTAAAGCAACACGATGTTGAAGT TGAGATAAAAGATAAGGGGCATTTAATTGAAAAACTCTGGGATTTAGTAGAGGACAAAGTTGTTCAACCAACATTCTTGT TAGAACATCCAGTGGAAATATCTCCTCTTGCAAAGAAACATAGAGAGGATCCAAGAGTTACTGAAAGATTTGAGCTTATA ATTTATGGTAGAGAAATGGCAAATGCATTTAGTGAATTGAATGATCCTGTTGATCAATACGAAAGATTTTTAAGGCAAGC TAAACTTCGTGAAGCTGGAGATGAGGAAGCCCAGATGATGGATAAAGATTTTGTTAGAGCTCTCGAATACGGTATGCCAC CTACTGGTGGTCTTGGTATAGGAATTGATAGATTGGTTATGCTTTTAACTAATTCGCCTACTATCAGAGATGTAATTGCA TTTCCACTGGTAAGACCAATTTCATTTGAAGAGGAAGAAATGAACTTAGAAGGGGGATCGCAAGAATGA Protein sequence : MLKEFREQRINEIKQISAKGVNPYPYKFEKTHSSQDIKAQFENLNPGEVKEDASVSTAGRIMSLRHHGKSAFFHIKDFFG RIQAYIRQDIVGKDVYEFFKEHIAIGDIVGVKGSVFKSKTGEVTILVKEIELLNKPLRPMPEKWHGIKDKEVLYRQRYVD MIANDETLNRFRIRFEIIKLIREFLNSKGFIEVETPILEYVTGGASARPFITHLNVFDIDMYMRIATELYLKRFIVGGFE KVYELGKNFRNEGLSYKHHPEFTSIEIYQAYADYEDMMNLTEELFVFIVEKLFGTTKVKYQDIEIDFSRPWRRVKMRDFI KEHLGVDILEDTEEKMLEVLKQHDVEVEIKDKGHLIEKLWDLVEDKVVQPTFLLEHPVEISPLAKKHREDPRVTERFELI IYGREMANAFSELNDPVDQYERFLRQAKLREAGDEEAQMMDKDFVRALEYGMPPTGGLGIGIDRLVMLLTNSPTIRDVIA FPLVRPISFEEEEMNLEGGSQE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 9e-102 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_002335305.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 5e-102 | 47 |
