Gene Information

Name : secA (THA_1422)
Accession : YP_002335207.1
Strain : Thermosipho africanus TCF52B
Genome accession: NC_011653
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1437532 - 1440102 bp
Length : 2571 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
GTGAAATTATTCGACAAAAATGAAAGGGTTATAAAAAAATATTGGAAAAAAGTAAATAAAATAAACAAGATAAACCTTGA
AAGTAAAAATTTAACCGAATTAATTAATTCCTTGAAAACAATTAAAGAAAATATTACTCCTGAAAATATTGACGAATATA
TTCCAGAAGTTTTTGCAATAGTAAGAGAAGTATCCAAACGAGTAATTGGATTAAGACCATTTGATGTACAACTTATAGGT
GCAATGGTTCTCCATGAAGGGAAAGTTGCAGAAATGAAAACAGGTGAAGGAAAAACTCTAGTTGCAACTATGCCGGTTGT
ATTAAATGCACTGCTTGGAAAAGGCGTTCACCTTGTAACTGTAAACGATTATCTTGCAAAAAGAGACGCTATGTGGATGG
GACCTATATATCTTGCTTTGGGACTTAGAGTAGGTGTTATAAATACACAAAACAAGTCATATGAAGTTATTTGGAAAAAT
GAGGAACTTGCAAAAAAGGCGTTAAATGAAAATTTGAGTGTTTGGCCTCAAGGTTTTAATGGAGAATTTCTTGAAGACGA
AGCAAAAAATAAAGAAGCACTAGAAGCTTATCAGGTTGAATTGAAGGAAATCAGCAGAAAAGAAGCATATGAGTGTGATA
TAACATACGGAACAAATACAGAGTTTGGGTTTGACTACTTAAGAGACAATCTTGTAATTGACCTGGAAGATAGAGTTCAA
AGAGGACATTTTTATGCAATAGTGGACGAAGTAGATAGCATCCTTATAGACGAGGCAAGAACTCCTTTAATAATAAGTGG
TCCATCAAAAACAAAAGCTTCAGATTATATTCGCTTCAATCAAATTGCTAAAAAACTCGTAAAAGACAAGCATTTTACTA
TAGACGAGCAGAAAAAATCTGTAATATTAACAGACGAAGGTATAGAATATATAGAAAAACTTTTAAATATAGAAAATCTC
TATGATCCTGAACACGTGAATAAAATGTATTTCTTATTAAATGCTTTAAAAGCACATTACCTGTTTAAAAAAGATGTAGA
TTATATTATTCATAACGGTGAGATTGTAATAGTAGACGAATTCACAGGTAGACTTCTTCCAGGAAGAAGATACAGTGGAG
GACTTCACCAAGCTATTGAAGCAAAAGAAGGAGTTAAAATCAAAGAAGAGTCGGTTACTTATGCAACTATAACATACCAG
AATTACTTTAGAATGTATGAAAAACTTTCCGGTATGACAGGAACTGCTAAAACAGAGGAAGAAGAATTTAAACAAATATA
CGGTATGGAAGTAGTTGTTATCCCAACTCACAAACCAATGATCAGAATAGATAGAGACGATTTAATTTACAGAACAGAAG
ACGAAAAATTTGAGGCAGTAGTAAAAGAAATAAAAAAACGCTATGAAAAAGGGCAACCTGTTTTAGTAGGTACAACATCC
ATTGAAAAAAGCGAAAGATTGAGTAAAATGCTAAGCAAAGAAAAAATACCTCACAACGTTTTAAATGCAAAACATCATGA
AAAGGAAGCTCAAATCGTTGCATTAGCTGGTCAAAAAGGTTCAGTTACAATTGCAACTAATATGGCTGGTAGGGGGACAG
ACATTAAATTAGGCCCCGGTGTAAAGGAATTAGGCGGGTTACTTATAATTGGAACTGAAAGACATGAAAGTAGAAGGATA
GACAACCAACTTAGAGGTAGAGCTGGAAGACAAGGTGACCCAGGTGAATCTATATTCTTCTTGTCCTTAGAAGATGATAT
TATAAGAATATTTGGTGGAGAAAAACTTGAAAAAATAATGAATCTAGTAAAAATTGAAAAAGGTGAGCCAATATATCATC
CTATGCTTACAAAATTAATAGAAAGGGTCCAAAAAAAGGTTGAAAGTATAAATTTTGGAATAAGAAAAAATTTACTTCAA
ATGGATACTGTTTTGGATACACAAAGACGAGCAATATATAGCTATAGAGAATATCTACTTTCAGGAAATATCGATGAACA
CTTCAACGATGCAATAGATGATTTTATTGAAAGAAGGCTCGAAGAATTTTGTGAAAAAGGCGTTTGTAATGTAGAAGAAA
TAAAAGAATCTTTAAAAATATTAAATATTAGCCTTGATAAACTGCCTGATACTAGAAATGAACTTAAAGAATATCTAAAA
AATCTTTTAATGGAAAAATTTGAAAATAAAAAGAAAGAATTGGGAGAAGATTTCCCAAAAATTGGAAAGTTCATAGCATT
GCGTGTAATAGATGAGAATTGGAGGCAGTACCTTGAAGAAGTTGAACACGTAAAAGAAGCAGTAAGCCTTAGAGCGTATG
GACAAAAAGATCCAATCTTGGAATTTAAAAAGGAAACATTTAGAATGTTTGATGAGATGATGGCTAAAATATTTGAGCAA
ACTATAATTTATACTTTAAACATTAGAAAAATCACTGATGAAGCCGAAAAAGAGTCAGAAAACGAGCTGAAAAAAATAAA
TACCCAACACGATGAATTTACACTTGTAAACAGAAAAGAGAGAAGAGTTGCAGAAAAGAAAGGAAAAAAGAAATTAAAGG
TCAAGAGGTGA

Protein sequence :
MKLFDKNERVIKKYWKKVNKINKINLESKNLTELINSLKTIKENITPENIDEYIPEVFAIVREVSKRVIGLRPFDVQLIG
AMVLHEGKVAEMKTGEGKTLVATMPVVLNALLGKGVHLVTVNDYLAKRDAMWMGPIYLALGLRVGVINTQNKSYEVIWKN
EELAKKALNENLSVWPQGFNGEFLEDEAKNKEALEAYQVELKEISRKEAYECDITYGTNTEFGFDYLRDNLVIDLEDRVQ
RGHFYAIVDEVDSILIDEARTPLIISGPSKTKASDYIRFNQIAKKLVKDKHFTIDEQKKSVILTDEGIEYIEKLLNIENL
YDPEHVNKMYFLLNALKAHYLFKKDVDYIIHNGEIVIVDEFTGRLLPGRRYSGGLHQAIEAKEGVKIKEESVTYATITYQ
NYFRMYEKLSGMTGTAKTEEEEFKQIYGMEVVVIPTHKPMIRIDRDDLIYRTEDEKFEAVVKEIKKRYEKGQPVLVGTTS
IEKSERLSKMLSKEKIPHNVLNAKHHEKEAQIVALAGQKGSVTIATNMAGRGTDIKLGPGVKELGGLLIIGTERHESRRI
DNQLRGRAGRQGDPGESIFFLSLEDDIIRIFGGEKLEKIMNLVKIEKGEPIYHPMLTKLIERVQKKVESINFGIRKNLLQ
MDTVLDTQRRAIYSYREYLLSGNIDEHFNDAIDDFIERRLEEFCEKGVCNVEEIKESLKILNISLDKLPDTRNELKEYLK
NLLMEKFENKKKELGEDFPKIGKFIALRVIDENWRQYLEEVEHVKEAVSLRAYGQKDPILEFKKETFRMFDEMMAKIFEQ
TIIYTLNIRKITDEAEKESENELKKINTQHDEFTLVNRKERRVAEKKGKKKLKVKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-101 44