Gene Information

Name : arcC (THA_1104)
Accession : YP_002334898.1
Strain : Thermosipho africanus TCF52B
Genome accession: NC_011653
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : -
Position : 1126374 - 1127315 bp
Length : 942 bp
Strand : -
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGAAAAAATTGGCAGTTGTTGCTATTGGTGGTAATGCAATTAATAGACCAGGAGAAAAACCAACAGCAGAAAATATGTT
CAAAAATATAAAAGTTACAGCATCATATCTTGCAGATATGATTGAATTAGGTTACAGAATAATAATAACTCACGGAAATG
GACCACAAGTTGGGAATCTACTAGTTCAACAGGATATTGCAAAGGATACTATTCCACCATTTCCAATGGATGTATTAGGT
GCAATGACCCAAGGATATCTTGGATATATGATTTCTCAAGAGTTGAAAAATGTATTAAATGAAAGAAAAATAGATAAGGA
AATTGCTACAGTAGTAACTCAAATTGTAGTAAATAAAGATGATCCAGGATTTAAAAATCCAACAAAACCAGTAGGTCCAT
TTTATAGCGAAGAAGAAGCAAAAAAGATTATGGAAGAAAAAGGTTGGATATTCAAAGAAGATGCTGGTAGAGGATGGAGA
AGAGTAGTTCCATCACCAATACCACTTGATGTTATTGAAAAAAGAACAATAAAAGACTTGGTAGAAAATGACGTTATAGT
AGTAGCAGGTGGTGGTGGTGGGATTCCAGTAATAATCGATGAAAAAGGAGAAATAAAAGGAGTAGAAGCAGTAATAGATA
AAGATAGAGCATCAGCATTAATAGCAAAAGAACTTGATGCAGATGAATTCATAATCCTTACAGCTGTAGAAAAAGTATAT
CTCAACTTTAACAAACCTGATCAAAAGCCACTTGATACAATCACAGTAAAGGAAGCTGAAAAATATATGAATGAAGGTCA
TTTTGCAAAAGGAAGTATGCTACCAAAAATAGAAGCCTGTATCTCCTTTGTAACATCAACAAATAGACCAGCACTCATCA
CCGATATGGAAAAACTAAAAGATGCACTAGAAGGAAAAACTGGAACAAGGATTATTCCATAA

Protein sequence :
MKKLAVVAIGGNAINRPGEKPTAENMFKNIKVTASYLADMIELGYRIIITHGNGPQVGNLLVQQDIAKDTIPPFPMDVLG
AMTQGYLGYMISQELKNVLNERKIDKEIATVVTQIVVNKDDPGFKNPTKPVGPFYSEEEAKKIMEEKGWIFKEDAGRGWR
RVVPSPIPLDVIEKRTIKDLVENDVIVVAGGGGGIPVIIDEKGEIKGVEAVIDKDRASALIAKELDADEFIILTAVEKVY
LNFNKPDQKPLDTITVKEAEKYMNEGHFAKGSMLPKIEACISFVTSTNRPALITDMEKLKDALEGKTGTRIIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 1e-62 50
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 1e-62 50
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 1e-62 50
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 1e-62 50
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 1e-62 50
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 1e-62 50
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 8e-57 47
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 1e-56 45