Gene Information

Name : kdsB (E2348C_0911)
Accession : YP_002328474.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 966058 - 966804 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTGTGGTCATTATTCCCGCGCGTTACGCGTCCACGCGTCTGCCCGGTAAACCATTGGTTGATATTAACGGCAA
ACCCATGATTGTTCATGTTCTTGAACGCGCGCGCGAATCAGGTGCCGAGCGCATCATCGTGGCAACCGATCATGAGGATG
TTGCCCGCGCTGTTGAAGCCGCTGGCGGCGAAGTATGTATGACGCGCGCCGATCATCAGTCAGGTACAGAACGATTGGCG
GAAGTTGTCGAAAAATGCGCATTCAGCGACGACACTGTGATCGTTAATGTGCAGGGTGATGAACCGATGATCCCTGCGAC
AATCATTCGTCAGGTTGCTGATAACCTCGCTCAGCGTCAGGTGGGTATGGCGACTCTGGCGGTGCCAATCCACAATGCGG
AAGAAGCGTTTAACCCGAATGCGGTGAAAGTGGTTCTCGACGCCGAAGGGTACGCACTGTACTTCTCTCGCGCCACCATT
CCGTGGGATCGTGATCGTTTTGTAAAAGACCTTGAAACCGTAGGCGATAACTTCCTGCGTCATCTTGGTATTTATGGCTA
CCGAGCAGGCTTTATCCGTCGTTATGTTACCTGGCAGCCAAGTCCGTTAGAACATATCGAAATGTTAGAGCAGCTTCGTG
TTCTGTGGTACGGCGAAAAAATCCACGTTGCTGTCGCCCAGGAAGTTCCTGGCACAGGTGTGGATACCCCTGAAGATCTC
AAGCGCGTTCGCGCCGAAATGCGCTAA

Protein sequence :
MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFVKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDL
KRVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-34 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-33 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-34 44