Gene Information

Name : thiC (E2348C_4301)
Accession : YP_002331757.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4523559 - 4525454 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTGCAACAAAACTGACCCGCCGCGAACAACGCGCCCAGGCCCAACATTTTATCGACACCCTGGAAGGCTCCGCCTT
TCCCAACTCAAAACGCATTTACATCACTGGCACACAACCCGGCGTGCGCGTGCCAATGCGTGAGATCCAGCTTAGCCCGA
CGCTAATTGGCGGCAGCAAAGAACAGCCGCAGTACGAAGAAAACGAAGCGATTCCGGTCTACGACACCTCCGGCCCATAT
GGCGATCCGCAGATTGCCATTAACGTGCAGCAAGGGCTGGCAAAACTACGCCAGCCGTGGATCGATGCGCGCGGCGATAC
CGAAGAACTTACCGTGCGCAGTTCCGATTACACAAAAGCGCGGCTGGCAGATGATGGCCTTGACGAGCTGCGTTTTAGCG
GCGTATTAACGCCAAAACGCGCCAAAGCAGGACGCCGCGTCACCCAACTGCACTACGCCCGCAAGGGTATCATCACGCCC
GAAATGGAATTCATCGCCATTCGCGAGAATATGGGTCGCGAGCGCATACGTAGCGAAGTTTTACGCCACCAGCATCCGGG
AATGAGCTTTGGCGCACGTCTTCCGGAAAATATCACTGCGGAATTTGTCCGTGATGAAGTTGCTGCCGGACGTGCGATTA
TCCCGGCCAACATTAATCATCCGGAATCGGAGCCGATGATTATTGGCCGTAACTTCCTGGTAAAAGTTAACGCCAATATC
GGCAACTCAGCGGTCACCTCTTCCATCGAAGAAGAAGTGGAAAAACTGGTATGGTCCACGCGCTGGGGAGCGGATACCGT
GATGGATCTTTCCACTGGTCGCTATATTCACGAAACCCGCGAGTGGATTTTGCGTAACAGCCCGGTGCCGATCGGTACAG
TGCCGATCTACCAGGCGCTGGAGAAGGTGAACGGGATCGCCGAAGATCTTACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAACAGGCCGAGCAAGGTGTGGATTACTTCACTATCCATGCGGGGGTGCTGCTGCGCTACGTGCCGATGACCGCGAAACG
CCTGACCGGTATCGTCTCTCGCGGCGGTTCGATTATGGCGAAATGGTGCCTCTCCCATCATCAGGAAAATTTCCTCTATC
AACACTTCCGCGAAATTTGTGAAATCTGTGCTGCTTATGACGTTTCGCTGTCGCTGGGCGACGGCCTGCGCCCCGGTTCT
ATTCAGGACGCCAACGATGAAGCACAGTTTGCCGAGCTGCATACGCTGGGCGAACTGACCAAAATCGCCTGGGAATATGA
CGTGCAGGTGATGATTGAAGGCCCAGGCCACGTGCCGATGCAGATGATTCGCCGCAATATGACCGAGGAGTTAGAGCACT
GCCACGAAGCGCCGTTTTACACTCTGGGGCCGCTAACTACCGATATCGCGCCGGGCTATGACCACTTCACGTCAGGGATT
GGTGCGGCGATGATTGGCTGGTTTGGCTGCGCGATGCTCTGCTACGTAACGCCGAAAGAGCATCTGGGCCTGCCAAATAA
AGAAGATGTTAAACAAGGGCTTATCACCTATAAGATTGCCGCTCACGCCGCCGACCTGGCGAAAGGGCATCCGGGCGCGC
AAATTCGCGATAACGCCATGTCGAAAGCCCGCTTCGAATTTCGCTGGGAAGACCAGTTTAATCTGGCCCTCGACCCGTTT
ACTGCCCGCGCTTATCACGATGAAACCCTGCCGCAAGAGTCCGGTAAAGTCGCCCATTTTTGCTCCATGTGTGGACCGAA
ATTCTGCTCGATGAAAATCAGCCAGGAAGTGCGTGATTACGCCGCCGCGCAAACCATTGAAGTGGGAATGGCGGATATGT
CGGAGAACTTCCGCGCCAGAGGCGGAGAAATCTACCTGCGTAAGGAGGAAGCGTGA

Protein sequence :
MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPY
GDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARKGIITP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68