Gene Information

Name : metB (E2348C_4243)
Accession : YP_002331701.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4443634 - 4444794 bp
Length : 1161 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACCATCGCAGTGCGTAGCGGGTTAAATGACGACGAACAGTATGGTTGCGTTGTCCCTCCCAT
CCATCTTTCCAGTACCTATAACTTTACCGGATTTAATGAACCGCGCGCGCATGATTACTCGCGGCGCGGCAACCCAACGC
GCGATGTGGTTCAGCGAGCGCTGGCAGAACTGGAAGGCGGTGCTGGTGCAGTACTTACTAATACCGGCATGTCCGCGATT
CACCTGGTAACGACCGTCTTTTTGAAACCTGGCGATCTGCTGGTTGCGCCGCACGACTGCTACGGCGGTAGCTATCGCCT
GTTCGACAGCCTGGCGAAACGCGGTTGCTATCGCGTGTTGTTTGTTGATCAAAGCGATGAACAGGCATTACGGGCAGCGC
TGGCAGAAAACCCCAAACTGGTACTGGTAGAAAGCCCAAGTAATCCATTGTTACGCGTCGTGGATATTGCGAAAATCTGC
CATCTGGCAAGGGAAGTCGGGGCGGTGAGCGTGGTGGATAACACCTTCTTAAGCCCGGCATTACAAAATCCACTGGCATT
AGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTGAACGGTCACTCTGACGTGGTGGCAGGCGTAGTGATTGCTA
AAGACCCGGACGTTGTCACTGAACTTGCCTGGTGGGCAAACAATATTGGCGTGACGGGCGGCGCGTTTGACAGCTATCTG
CTGCTGCGCGGGTTGCGAACGCTGGTGCCGCGAATGGAGCTGGCACAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGGAAAATCAGGGGCATGAAATTGCCGCGCGCCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGCGATGAGCAGACGCTGCGTCGTTTCCTGGGCGGGCTGTCGTTG
TTTACGCTGGCGGAATCATTAGGGGGAGTGGAAAGTTTAATCTCTCACGCCGCAACCATGACACATGCAGGCATGGCGCC
AGAAGCGCGTGCTGCCGCCGGGATCTCCGAGACGCTGCTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQSDEQALRAALAENPKLVLVESPSNPLLRVVDIAKIC
HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-58 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-59 43