Gene Information

Name : escU (E2348C_3960)
Accession : YP_002331422.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaU
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4792
EC number : -
Position : 4129023 - 4130060 bp
Length : 1038 bp
Strand : -
Note : member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli

DNA sequence :
ATGAGTGAAAAAACAGAAAAGCCCACACCCAAAAAACTGAGGGATCTAAAAAAGAAGGGCGATGTAACAAAAAGTGAAGA
GGTAATGGCTGCAGTGCAGTCATTAATCTTATTTTCATTTTTTTCTTTATATGGCATGAGTTTTTTTGTTGATATAGTTG
GGTTAGTTAATACGACAATAGACTCGCTAAATAGACCGTTTTTGTATGCCATTCGAGAAATATTAGGTGCGGTGTTAAAT
ATATTTTTATTATATATTTTGCCAATTTCTTTGATTGTCTTTGTTGGAACTGTTACGACTGGTGTATCACAAATAGGATT
CATCTTTGCGGTTGAAAAAATAAAACCATCGGCTCAGAAGATTAGTGTAAAAAATAACCTGAAAAATATTTTTTCTGTAA
AGAGCATTTTTGAGCTACTTAAATCAGTATTTAAGTTAGTGATAATTGTTCTCATTTTTTATTTTATGGGGCATTCATAT
GCAAATGAGTTTGCTAATTTCACAGGACTGAACGCATATCAAGCTCTTGTCGTTGTTGCCTTTTTTGTTTTTCTTTTATG
GAAAGGCGTGCTATTCGGATATCTACTCTTTTCAGTATTTGATTTCTGGTTCCAGAAGCATGAGGGACTGAAGAAAATGA
AAATGAGTAAAGATGAGGTGAAACGAGAAGCCAAGGATACTGATGGTAACCCTGAAATTAAAGGGGAGCGCCGTCGCCTT
CATTCCGAGATACAAAGTGGAAGTTTGGCGAATAACATCAAAAAATCAACCGTTATTGTTAAAAACCCGACTCACATTGC
GATTTGCCTATACTATAAACTTGGGGAGACTCCATTACCTTTAGTTATTGAAACAGGAAAAGATGCCAAAGCTCTACAGA
TCATTAAACTGGCTGAACTCTATGATATTCCAGTGATTGAAGATATTCCTTTAGCAAGAAGTCTCTATAAGAATATACAT
AAAGGACAATATATAACAGAAGACTTTTTTGAACCTGTGGCACAATTGATTCGTATTGCGATAGACCTTGATTATTAA

Protein sequence :
MSEKTEKPTPKKLRDLKKKGDVTKSEEVMAAVQSLILFSFFSLYGMSFFVDIVGLVNTTIDSLNRPFLYAIREILGAVLN
IFLLYILPISLIVFVGTVTTGVSQIGFIFAVEKIKPSAQKISVKNNLKNIFSVKSIFELLKSVFKLVIIVLIFYFMGHSY
ANEFANFTGLNAYQALVVVAFFVFLLWKGVLFGYLLFSVFDFWFQKHEGLKKMKMSKDEVKREAKDTDGNPEIKGERRRL
HSEIQSGSLANNIKKSTVIVKNPTHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAELYDIPVIEDIPLARSLYKNIH
KGQYITEDFFEPVAQLIRIAIDLDY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escU YP_003236100.1 T3SS structure protein EscU Virulence LEE Protein 4e-152 100
escU AAC38372.1 EscU Virulence LEE Protein 3e-152 100
ECs4580 NP_312607.1 secretion system apparatus protein SsaU Virulence LEE Protein 5e-152 99
escU AAC31525.1 L0046 Virulence LEE Protein 4e-152 99
escU ACU09470.1 secretion system apparatus protein SsaU Virulence LEE Protein 4e-152 99
escU NP_290280.1 secretion system apparatus protein SsaU Virulence LEE Protein 5e-152 99
escU CAI43886.1 EscU protein Virulence LEE Protein 4e-149 98
escU CAC81850.1 EscU protein Virulence LEE II Protein 1e-148 98
escU YP_003232141.1 secretion system apparatus protein SsaU Virulence LEE Protein 1e-148 98
escU AAK26703.1 EscU Virulence LEE Protein 4e-149 98
escU YP_003223487.1 T3SS structure protein EscU Virulence LEE Protein 5e-149 98
escU AAL57530.1 EscU Virulence LEE Protein 4e-149 98
unnamed AAL06357.1 EscU Virulence LEE Protein 2e-143 91
escU AFO66307.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-117 75
escU AFO66403.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-117 75
YPO0273 YP_002345355.1 secretion system apparatus protein SsaU Virulence Not named Protein 3e-62 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
escU YP_002331422.1 secretion system apparatus protein SsaU VFG0718 Protein 2e-152 100
escU YP_002331422.1 secretion system apparatus protein SsaU VFG0824 Protein 2e-152 99