Gene Information

Name : tir (E2348C_3941)
Accession : YP_002331403.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Virulence
Product : translocated intimin receptor Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4113830 - 4115482 bp
Length : 1653 bp
Strand : -
Note : -

DNA sequence :
ATGCCTATTGGTAACCTTGGTAATAATGTAAATGGCAATCATTTAATTCCCCCTGCGCCGCCACTACCTTCACAAACAGA
CGGCGCGGCACGGGGAGGAACTGGTCATCTAATTAGCTCTACAGGAGCATTAGGATCTCGTTCATTGTTTTCTCCCCTGA
GAAATTCTATGGCTGATTCTGTCGATTCCAGAGATATTCCAGGACTTCCTACAAACCCATCGAGGCTTGCTGCAGCTACA
TCTGAGACATGCTTGCTTGGAGGATTTGAAGTTCTCCATGATAAGGGGCCACTTGATATTCTCAATACGCAAATTGGACC
CTCTGCATTTCGTGTTGAAGTGCAGGCAGATGGTACTCATGCCGCTATTGGAGAAAAAAATGGTTTGGAGGTTAGCGTTA
CATTAAGTCCTCAAGAATGGAGCAGCTTGCAATCTATTGATACTGAGGGTAAAAACAGATTTGTTTTTACCGGGGGACGT
GGCGGTAGTGGGCATCCGATGGTCACTGTCGCATCAGATATCGCGGAAGCTCGTACGAAAATACTGGCCAAATTAGACCC
AGACAATCATGGAGGACGTCAACCCAAGGACGTTGATACGCGTTCTGTTGGTGTTGGCAGCGCTTCGGGAATAGATGATG
GCGTTGTTAGCGAAACCCATACTTCAACAACAAATTCCAGCGTTCGCTCAGATCCTAAATTCTGGGTTTCTGTCGGCGCA
ATTGCTGCTGGTTTAGCGGGACTGGCGGCAACTGGTATTGCACAGGCGTTGGCTTTGACACCGGAACCGGATGATCCTAC
AACCACCGATCCTGATCAGGCCGCAAATGCTGCAGAAAGTGCAACAAAAGATCAGTTAACGCAAGAAGCATTCAAGAACC
CTGAGAACCAGAAAGTTAACATCGATGCGAACGGAAATGCTATTCCGTCTGGGGAATTAAAAGATGATATTGTTGAGCAA
ATAGCACAACAAGCTAAAGAGGCTGGTGAGGTGGCCAGACAGCAGGCTGTTGAAAGCAATGCACAGGCGCAGCAGCGATA
TGAGGATCAGCATGCCAGACGTCAGGAGGAATTACAGCTTTCATCGGGTATTGGTTACGGCCTCAGCAGTGCATTGATTG
TTGCTGGGGGAATTGGTGCTGGTGTAACGACTGCGCTCCATAGACGAAATCAGCCGGCAGAACAGACAACTACTACAACA
ACACATACGGTAGTGCAGCAACAGACCGGAGGGAATACCCCAGCACAAGGTGGCACTGATGCCACAAGAGCAGAAGACGC
TTCTCTGAATAGACGTGATTCGCAGGGGAGTGTTGCATCGACACACTGGTCAGATTCCTCTAGCGAAGTGGTTAATCCAT
ATGCTGAAGTTGGGGGGGCTCGGAATAGTCTATCGGCTCATCAGCCAGAAGAGCATATTTATGATGAGGTCGCTGCAGAT
CCTGGTTATAGCGTTATTCAGAATTTTTCAGGGAGCGGCCCAGTTACCGGAAGGTTAATAGGAACTCCAGGGCAAGGTAT
CCAAAGTACTTATGCGCTTCTGGCAAACAGCGGCGGATTGCGTTTAGGTATGGGAGGATTAACGAGTGGTGGCGAGAGCG
CAGTAAGTTCTGTAAATGCCGCACCAACGCCGGGACCAGTACGTTTCGTTTAA

Protein sequence :
MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADSVDSRDIPGLPTNPSRLAAAT
SETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADGTHAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGR
GGSGHPMVTVASDIAEARTKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSVGA
IAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQ
IAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTT
THTVVQQQTGGNTPAQGGTDATRAEDASLNRRDSQGSVASTHWSDSSSEVVNPYAEVGGARNSLSAHQPEEHIYDEVAAD
PGYSVIQNFSGSGPVTGRLIGTPGQGIQSTYALLANSGGLRLGMGGLTSGGESAVSSVNAAPTPGPVRFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tir AAC38390.1 Tir Virulence LEE Protein 0.0 100
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 7e-162 84
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 6e-162 84
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 2e-162 84
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 2e-162 84
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 3e-142 79
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 5e-118 66
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 6e-118 66
espE CAC81869.1 EspE protein Virulence LEE II Protein 7e-120 66
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 9e-120 66
tir AAK26722.1 Tir Virulence LEE Protein 5e-120 66
tir AAL57549.1 Tir Virulence LEE Protein 5e-120 66
tir AAC31506.1 L0027 Virulence LEE Protein 7e-105 60
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 7e-105 60
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 7e-105 60
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 4e-106 60
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 1e-104 60
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 4e-106 60
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 1e-104 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tir YP_002331403.1 translocated intimin receptor Tir VFG0737 Protein 0.0 100
tir YP_002331403.1 translocated intimin receptor Tir VFG0805 Protein 4e-105 60