Gene Information

Name : topB (E2348C_1890)
Accession : YP_002329410.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1949538 - 1951493 bp
Length : 1956 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGCGCGCGCCATTGCTGATGTCCTGCCTAAACCGCACCGGAAAGGCGA
TGGCTTTATCGAGTGCGGTAATGGTCAGGTGGTGACCTGGTGTATCGGTCACCTGCTTGAGCAGGCGCAGCCAGACGCCT
ACGACAGCCGCTATGCGCGCTGGAATCTTGCGGATTTGCCAATTGTCCCGGAAAAGTGGCAATTACAGCCCCGACCCTCC
GTGACTAAACAACTTAATGTCATCAAACGCTTCCTGCATGAAGCCAGCGAAATCGTTCACGCCGGAGACCCGGATCGCGA
AGGGCAACTGCTGGTGGATGAAGTGCTGGACTACCTGCAACTGGCACCGGAAAAGCGCCAGCAGGTACAGCGTTGTTTGA
TAAACGACCTGAACCCGCAGGCGGTTGAGCGGGCGATCGATCGTCTTCGCTCCAATAGCGAGTTTGTACCGCTGTGCGTT
TCTGCACTGGCGCGAGCCCGAGCTGACTGGCTGTACGGCATCAATATGACCCGCGCTTACACCATTCTCGGTCGCAATGC
CGGTTATCAGGGCGTACTTTCCGTGGGACGCGTGCAGACGCCCGTACTCGGACTGGTGGTGCGCCGCGACGAAGAGATTG
AAAACTTCGTGGCGAAAGATTTCTTTGAAGTCAAAGCACATATCGTGACACCTGCCGATGAGCGGTTCACCGCTATCTGG
CAACCGAGCGAAGCGTGTGAACCGTACCAGGATGAAGAAGGGCGCTTGTTACATCGTCCACTGGCGGAGCATGTGGTTAA
CCGCATTAGTGGTCAACCAGCTATTGTCACCAGCTATAACGATAAACGGGAATCAGAATCCGCGCCGCTACCGTTTTCTC
TTTCGGCGTTGCAGATTGAAGCGGCTAAACGTTTTGGTCTGAGCGCGCAGAACGTGCTTGATATCTGCCAGAAGCTGTAC
GAAACGCACAAGCTAATCACTTATCCGCGTTCCGATTGCCGCTATTTGCCAGAAGAACATTTTGCCGGACGCCACGCGGT
GATGAATGCTATCAGCGTTCATGCACCGGATCTGTTGCCGCAGCCAGTGGTAGATCCAGATATACGCAACCGCTGTTGGG
ATGACAAAAAGGTCGATGCGCACCACGCCATCATTCCGACCGCACGGAGTTCTGCGATCAACCTGACGGAGAACGAAGCG
AAGGTCTATAACCTGATTGCCCGTCAGTACTTGATGCAGTTCTGCCCGGATGCGGTGTTCCGCAAGTGTGTTATCGAACT
GGACATTGCCAAAGGCAAATTTGTCGCTAAAGCCCGTTTTCTTGTTGAAGCAGGCTGGCGCACGCTGTTAGGCAGCAAAG
AGCGCGATGAAGAAAACGACGGCACGCCGCTGCCTGTGGTGGCGAAAGGCGATGAATTGTTGTGCGAAAAAGGCGAAGTG
GTAGAGCGGCAAACCCAACCGCCGCGCCATTTTACCGATGCAACACTGCTTTCGGCGATGACCGGGATCGCGCGCTTTGT
GCAGGACAAAGATCTGAAAAAGATCCTTCGTGCGACCGATGGTCTGGGGACAGAAGCAACGCGTGCCGGGATTATTGAAC
TGTTGTTCAAGCGGGGTTTCCTGACCAAAAAAGGGCGCTATATCCACTCCACCGACGCCGGAAAAGCGCTATTCCATTCG
CTGCCAGAAATGGCGACGCGACCGGACATGACCGCGCACTGGGAATCGGTGCTGACGCAAATCAGCGAAAAGCAGTGTCG
CTATCAGGACTTTATGCAGCCGCTGGTGGGGACATTGTACCAGTTGATTGATCAGGCAAAGCGCACGTCGGTAAGGCAGT
TTCGGGGAATAATGGCTCCCGGCGGTGGAGAGGGGAAGATAAAGGATTCGCCACGCAAGAGAGCGCCGAAAAAAAGCCCG
CCATCAGAAGAGGCGGGCAATGGAGTGATAACATAA

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEA
KVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLVEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHS
LPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGGGEGKIKDSPRKRAPKKSP
PSEEAGNGVIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-101 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-110 41