Gene Information

Name : cvrA (E2348C_1310)
Accession : YP_002328850.1
Strain : Escherichia coli E2348/69
Genome accession: NC_011601
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1346574 - 1348310 bp
Length : 1737 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCACAACAATAATTAGCCTTTTCATCTTAGGATCCATCCTTGTCACCAGCAGTATTTTACTTAGTTCATTTTC
TTCCCGTCTTGGCATTCCCATTCTGGTTATTTTTCTGGCGATCGGCATGCTGGCGGGGGTTGATGGCGTCGGCGGTATCC
CGTTTGATAATTACCCCTTCGCCTACATGGTAAGTAACCTGGCGCTGGCGATTATTTTGCTCGACGGTGGGATGCGCACT
CAGGCCAGTTCCTTTCGTGTGGCGTTAGGACCGGCACTGTCGCTGGCGACGCTGGGCGTACTTATCACCTCTGGTTTAAC
CGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGATTATTAATCGGCGCTATCGTCGGCTCCACCGATG
CTGCAGCGGTCTTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACGTGTTGGCTCGACGCTGGAAATTGAATCCGGCAGT
AATGATCCAATGGCTGTCTTTCTGACGATTACCCTGATTGCGATGATCCAGCAGCATGAAAGCAGTGTCAGCTGGATGTT
CGTGGTCGATATTCTGCAGCAATTTGGCCTCGGGATTGTCATCGGGCTTGGCGGTGGTTATTTACTGCTGCAAATGATTA
ATCGCATCGCCCTGCCCGCCGGATTATATCCATTGCTGGCATTAAGCGGCGGTATTTTAATTTTTGCTTTAACCACGGCG
CTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGCTGGGTAATCGGCCGATTCGCAACCGCTACGGCAT
CCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATGTTCCTGGTGCTGGGGCTATTGGTTAACCCAAGCG
ATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCCGCATGGATGATTTTCTTCGCCCGTCCTCTTTCGGTATTTGCC
GGATTGCTACCGTTCCGTGGCTTCAATCTGCGTGAGCGCGTGTTTATCAGCTGGGTAGGATTACGCGGCGCGGTGCCGAT
TATTCTGGCTGTGTTCCCGATGATGGCGGGGCTGGAGAATGCGCGACTGTTCTTTAATGTCGCCTTCTTTGTGGTCCTGG
TTTCACTGCTATTGCAGGGAACATCACTCTCGTGGGCGGCGAAAAAAGCCAAAGTGGTCGTTCCGCCAGTGGGACGTCCG
GTGTCACGCGTTGGCCTGGATATTCATCCGGAAAATCCGTGGGAGCAGTTTGTTTATCAATTGAGTGCCGATAAATGGTG
CGTAGGCGCGGCACTGCGTGATTTGCATATGCCAAAAGAGACGCGTATTGCGGCACTGTTTCGTGATAACCAGTTGCTTC
ATCCCACCGGCAGCACCCGACTGCGCGAAGGCGATGTGTTGTGTGTAATTGGTCGGGAACGCGATCTCCCGGCGCTCGGT
AAACTGTTCAGCCAGTCGCCGCCGGTCGCGCTGGATCAACGCTTCTTTGGTGACTTCATTCTCGAAGCCAGCGCCAAATA
TGCTGATGTGGCGCTGATATATGGCCTGGAAGACGGGCGAGAATATCGCGATAAGCAGCAAACGCTGGGTGAAATCGTCC
AGCAGTTGTTAGGCGCAGCACCGGTTGTCGGTGACCAGGTAGAGTTTGCCGGGATGATCTGGACGGTGGCCGAGAAAGAA
GATAATGAAGTGTTGAAGATTGGTGTTCGGGTAGCGGAGGAAGAAGCCGAATCTTAA

Protein sequence :
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99