Gene Information

Name : thiC (ABBFA_003281)
Accession : YP_002327157.1
Strain : Acinetobacter baumannii AB307-0294
Genome accession: NC_011595
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3491531 - 3493408 bp
Length : 1878 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACCAATTAACGAATCTCTCTTCTGCTGAAATTTCAGCACAACATGAACAAGATGCAAAAGACTTAACCCGCATCTT
ACCCGCTTCTAAAAAAGTTTATATTGAAGGCTCTCGCCCTGATATTCAGGTTCCAATGCGAGAAATTTCTTTAACCGATA
CTCCAACTGGCCTTGGTGGAGAGCACAACCCACCTATTATGGTATATGACACTTCAGGTGTTTATACTGACCCGAATGTT
CAAATTGATTTAAACAAAGGTTTACCTTCAGTTCGTCAAAAATGGATTGAAGAGCGTAACGATACTGACGTTCTTTCTGG
CCTAACTTCAAAGTTTGGACAGGAGCGTTTAAAAGATATTCGTACTGCTGATATTCGCTTTGCACATATTCAAAACCCAC
GCCGCGCTAAAGCAGGCAAAAATGTCACTCAAATGCACTATGCCAAGCAAGGTATTATCACGCCTGAAATGGAATATATT
GCAATTCGTGAAAATCAGCGTCAACGCGAAGCTGTAGATATGCGCCAGCACCCAGGTCAAAACTTTGGTGCGAAAAACTT
AAAAGAAATTACACCTGAGTTTGTTCGCCAAGAAGTTGCCGAAGGCCGCGCTATTATTCCTGCCAACATTAACCACCCAG
AACTTGAACCAATGATTATTGGCCGTAATTTCTTGGTTAAGATTAATGCCAATATTGGTAACTCGGCGCTTGGTTCTTCA
ATTGATGAAGAAGTTGCGAAAATGACATGGGCAACCCGTTGGGGCGCTGACACCATTATGGACTTGTCTACAGGTAAGAA
CATTCATGAAACACGTGAATGGATTATTCGTAACTCACCAGTTCCAATCGGTACCGTACCAATTTATCAAGCACTTGAAA
AAGTTGATGGTGTTGCCGAGAACCTGACTTGGGAAATCTTTAAAGACACGCTTATTGAACAAGCTGAACAAGGTGTTGAC
TACTTCACCATTCACGCAGGTGTATTGCTTCGCTATGTGCCACTTACAGCAAACCGTTTAACAGGTATTGTATCTCGTGG
TGGTTCAATCATGGCGCAGTGGTGTCTCGCTCATCATGAAGAGAACTTCTTATACACACACTTCGATGAAATCTGTGAAA
TCATGAAAGCCTATGATGTGTCATTTAGCTTAGGCGATGGCTTACGTCCGGGTTGTATTCAAGATGCAAATGACGAAGCG
CAGTTCAGCGAACTTAAAACACTGGGTGAGTTGACTCACCGTGCATGGGAACATGATGTTCAGGTCATGATCGAAGGTCC
GGGTCACGTACCAATGCATATGATTAAAGAGAACATGGACTTACAGTTAGAAGTGTGTAAAGAAGCTCCATTCTATACAC
TTGGGCCTTTAACCACAGATATCGCTCCGGGTTATGACCACATTACTTCTGCTATTGGTGCAGCCATGATCGGCTGGTAT
GGCACAGCAATGCTTTGCTATGTGACACCTAAAGAACATTTAGGTTTGCCAAACAAGAAAGATGTAAAAGACGGAATTAT
TACCTACAAGATTGCAGCACACGCAGCCGATCTTGCCAAAGGTCATCCGGGTGCACAGGTTCGTGATAATGCCTTGTCTA
AAGCACGTTTCGAATTCCGTTGGGACGATCAGTTCAACCTAAGCCTAGACCCAGATACAGCACGCAGCATGCATGACGAG
ACTTTACCAAAAGAAGCGCATAAATCTGCTCACTTTTGCTCAATGTGTGGTCCAAAATTCTGTTCGATGAAAATCACCCA
GAATGTTCGTGACTATGCCAACAATCTCACCAATAGCGATTCAGAGGTTGAAGAAGGCCTCAAAGCGATGAAAGAGGTTT
ATCAAGAGCAAGGACAGAAACTGTATCATAAAGTGTAA

Protein sequence :
MNQLTNLSSAEISAQHEQDAKDLTRILPASKKVYIEGSRPDIQVPMREISLTDTPTGLGGEHNPPIMVYDTSGVYTDPNV
QIDLNKGLPSVRQKWIEERNDTDVLSGLTSKFGQERLKDIRTADIRFAHIQNPRRAKAGKNVTQMHYAKQGIITPEMEYI
AIRENQRQREAVDMRQHPGQNFGAKNLKEITPEFVRQEVAEGRAIIPANINHPELEPMIIGRNFLVKINANIGNSALGSS
IDEEVAKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAENLTWEIFKDTLIEQAEQGVD
YFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEA
QFSELKTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWY
GTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDE
TLPKEAHKSAHFCSMCGPKFCSMKITQNVRDYANNLTNSDSEVEEGLKAMKEVYQEQGQKLYHKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 100
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 100
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 72