Gene Information

Name : lysS (ABBFA_002612)
Accession : YP_002326510.1
Strain : Acinetobacter baumannii AB307-0294
Genome accession: NC_011595
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2771642 - 2773171 bp
Length : 1530 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACGCAACAAAACGCTCAATCGACTTCTGAACCAACTATTTCCGAAAACGATTTAATTGCACAGCGTCATGCCAAATT
AAAGCAAATCCAAGATGTTGCAAAGGAAACTGGAAAGAGTCCTTGGCCAAATACATTCAAACGTGAACATTACGCTGCTG
ATTTACAAGAACAATTTAAAGATCAGTCTAAAGAACAAATCGAAAGCGCTGAACATGTTTATGTAAAAGTTGCTGGCCGT
GTCATGTTAAACCGTGGTTCTTTCATGGTGATTCAAGACATGACTGGTCGTATCCAATTATATGTTGACCGTAAAGGTTT
ACCAAAAGATACGCTTGAAACTATTAAAGGTTTAGACCTTGGCGATATTATTGCTGCTGAAGGTTATATCGGTCGTTCTG
GCAAAGGTGACTTATATGTACACCTTGAAGGTTTTGAACTTCTTACAAAATCGCTTCGTCCATTGCCGGATAAATTTCAT
GGTTTGAACGACACAGAAGTTAAATATCGTAAGCGTTATCTTGACTTAATTGTGAATGAAGAAACGCGTAAGACTTTTGA
AATTCGTGCCAAAGTCGTTGCAGGTATTCGCGCATTTTTAACTAATGAACGTTTCATGGAAGTTGAAACGCCAATGATGC
ATGTGATTCCGGGTGGCGCGTCTGCACGTCCGTTTGAAACGCATCATAATGCTTTAGATATGCCATTATTCTTGCGTATC
GCACCTGAGCTTTATTTAAAGCGTTTAGTAGTGGGTGGTTTTGAGCGTGTGTTCGAAATTAACCGTAACTTCCGTAATGA
AGGGGTGTCAACACGTCATAACCCTGAATTTACCATGATCGAGTTTTATCAGGCATATGCTGATTATAAAGACTTGATGG
CTTTAACTGAAAACATGCTTGAAAAGTTAGCTCTTGATATTTTAGGTACAACTGATGTGCCTTACCAAGGTGAAGTGTTT
AGCTTTAAAGGACCATTCAAGAAAATCTCTATGTTTGATGCGATTTTGGAGAATAATCCGCAGTTCACGCCTGAAAATGT
AGGCGATCGTGAATTCCTTGCAAAATTTGTTCGTGAGGAATTAAAAGAAGAAGTTAAACCTGGTTTTGGTTTAGGTAAGC
TTCAAACAATCGTATTTGAAGAAACGGTTGAGACTAAACTTCGTCAGCCTACTTTTATTACTGAGTACCCAGCAGAGACT
TCTCCACTTGCTCGCCGTAATGATGATAATCCGCACATTACTGATCGTTTTGAGTTCTTTATTGGTGGCCGTGAATTGGC
AAACGGCTTTAGTGAGTTAAATGATCCGATTGATCAGGCTGAACGTTTCCAAGCGCAAGTTGCTGAAAAAGATGCTGGTG
ATGATGAAGCAATGCATTACGATGCAGAGTTTGTTGAAGCACTTGAATATGGTTTACCTCCAACAGCGGGTGAAGGTATT
GGTATTGACCGTTTGGTTATGCTTTTTGCAGATGCACCAAGTATTCGTGATGTGATTTTGTTCCCGCATATGCGTCGTAA
AGAAGGTTAA

Protein sequence :
MTQQNAQSTSEPTISENDLIAQRHAKLKQIQDVAKETGKSPWPNTFKREHYAADLQEQFKDQSKEQIESAEHVYVKVAGR
VMLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFH
GLNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHHNALDMPLFLRI
APELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLALDILGTTDVPYQGEVF
SFKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQPTFITEYPAET
SPLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALEYGLPPTAGEGI
GIDRLVMLFADAPSIRDVILFPHMRRKEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-128 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002326510.1 lysyl-tRNA synthetase VFG1668 Protein 1e-128 55