Gene Information

Name : ABBFA_001365 (ABBFA_001365)
Accession : YP_002325268.1
Strain : Acinetobacter baumannii AB307-0294
Genome accession: NC_011595
Putative virulence/resistance : Virulence
Product : acetaldehyde dehydrogenase 2(acetaldehyde dehydrogenaseII) (ACDH-II)
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 1470146 - 1471657 bp
Length : 1512 bp
Strand : -
Note : [C] COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence : 
ATGCGCTATATCGATCCAAATCAACCAGGCTCAAAAGTTCAATTTAAATCACAATATGAAAATTTTATTGGCGGTGAATG
GGTTGCACCTCTAAAGGGTGAATATTTTGATAATGTGTCACCAGTGGATGGAAAAGCTTTCACACGCATTCCACGCTCTA
GTGCTGAAGATATTGAACTTGCTTTAGATGCAGCACACAAAGCGAAAGCTTCATGGAATAAATCTTCACCGACTACACGT
TCTAATATACTTTTAAAAATTGCTGATCGTTTAGAAGCAAATCTTGAAATGCTTGCGGTTGCAGAAACTTGGGACAACGG
TAAAGCAGTTCGTGAAACTTTAGCAGCTGACCTTCCACTTGCAATCGACCATTTCCGTTATTTCGCAGGATGTATTCGTG
CTCAAGAAGGCGGCATCTCTGAAATTGATGAAGATACCATTGCCTACCATTTCCATGAACCACTAGGTGTGGTTGGTCAA
ATCATTCCATGGAACTTCCCGATTTTAATGGCTGCATGGAAGCTCGCTCCCGCTTTGGCGGCTGGTAACTGTGTGGTGAT
TAAGCCAGCTGAGCAAACTCCGGTAGGTATTTTGTTGGTTGCCGAACTCATCCAAGATATCTTACCGCCGGGCGTACTTA
ATATTGTGAATGGTTTCGGTGCAGAAGTTGGCCGTCCGTTAGCGACAAGCCCACGTATTGCAAAAATTGCGTTCACAGGT
TCAACTCAAACTGGGCAAATGGTGATGCAATATGCGACCGAAAATATTATTCCAGTCACGCTAGAGCTTGGCGGCAAGTC
ACCGAACCTTTTCTTTGAAGACATCATGGATAAAGAAGATGACTTCTTAGAAAAAACGCTGGAAGGTTTTGCCATGTTTG
CCTTAAACCAAGGTGAAGTATGTACTTGCCCTTCTCGTGCTTTAGTACAAGAAAGTATTGCTAATCAATTCTTAGAGTTG
GCCGTCGAACGTGTAAAACGTATTAAAACTGGTCATCCTCTCGATACTGAAACCATGATTGGTGCTCAAGCATCTTTGCA
ACAACAAGAGAAAATCTTACGTTGTATTAATACGGGCCGAGAAGAAGGTGCAGAACTCTTACTTGGTGGTAGTGGCCGTA
AAGAAGTAGGTGATGGTTTCTATGTTGATCCGACTATTTTTAAAGGCCACAACAGCATGCAAGTTTTCCAAGAAGAAATT
TTTGGTCCTGTACTGGCTGTGACAACATTTAAAGACTTTGACGATGCAATCAAAATTGCCAACGACACTATGTATGGTTT
AGGTGCAGGTGTATGGTCACGTTCAGCCCATATTTCTTACCGTGCTGGTCGTGCTATTGAGGCGGGTCGTGTCTGGACAA
ACTGCTATAACATCTACCCTGCTCATGCTGCATTTGGTGGCTACAAGAAGTCTGGTATTGGTCGTGAAAACCATAAGATG
ATGCTAGATCACTATCAACAAACCAAAAACTTGTTGGTGAGTTATTCAACCAAACCAATGGGCTTCTTCTAA

Protein sequence : 
MRYIDPNQPGSKVQFKSQYENFIGGEWVAPLKGEYFDNVSPVDGKAFTRIPRSSAEDIELALDAAHKAKASWNKSSPTTR
SNILLKIADRLEANLEMLAVAETWDNGKAVRETLAADLPLAIDHFRYFAGCIRAQEGGISEIDEDTIAYHFHEPLGVVGQ
IIPWNFPILMAAWKLAPALAAGNCVVIKPAEQTPVGILLVAELIQDILPPGVLNIVNGFGAEVGRPLATSPRIAKIAFTG
STQTGQMVMQYATENIIPVTLELGGKSPNLFFEDIMDKEDDFLEKTLEGFAMFALNQGEVCTCPSRALVQESIANQFLEL
AVERVKRIKTGHPLDTETMIGAQASLQQQEKILRCINTGREEGAELLLGGSGRKEVGDGFYVDPTIFKGHNSMQVFQEEI
FGPVLAVTTFKDFDDAIKIANDTMYGLGAGVWSRSAHISYRAGRAIEAGRVWTNCYNIYPAHAAFGGYKKSGIGRENHKM
MLDHYQQTKNLLVSYSTKPMGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 8e-101 64
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 1e-100 63
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 1e-100 63
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 9e-101 63
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 3e-100 63
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 3e-100 63
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 1e-100 63
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 1e-100 63
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-135 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-144 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-144 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-144 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-143 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ABBFA_001365 YP_002325268.1 acetaldehyde dehydrogenase 2(acetaldehyde dehydrogenaseII) (ACDH-II) VFG0082 Protein 5e-136 63