Gene Information

Name : Blon_0748 (Blon_0748)
Accession : YP_002322230.1
Strain : Bifidobacterium longum JCM 1222
Genome accession: NC_011593
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 868917 - 870149 bp
Length : 1233 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: blo:BL0078 cystathionine beta-lyase

DNA sequence :
ATGACCAGATTCAATACTCAGCTCGTTCACGGACTGCCGGTTGACGACAATGACACCGGAGCAGTGAATCCGCCGATCTA
CAATTCGACGACATATGCCTTTGAGAGGGTCGATGCGATGCCCCGCTACGATTACGCGCGCAGCGGCAACCCCACGCGTG
ATTTCCTGGAGCGGCAGATCGCCCAGCTTGAACAGGGAAAGCGTGGTTTTGCGTTCGCCTCCGGTCTGGCTGCGATCCAT
GCGGTGCTCAGTACCTTCAAGCCCGGCGACCGTATCGTCGTGGGAGACAATATCTACGGTGGAACGTACTCGCAGCTCAA
TGAGTTCTTCACCCGTTGGGGGCTTGTGGTCGAATCGGTCAATACCAGGGATGACGCCGCTTTGGAGTCCGCAGTGCGGG
GCGATCGCGCGAACGGCGTCGCGCCCGCCCGGGCCGTCTATTTCGAGACCCTGACCAATCCGCTGCTCAAGGTCAATGAC
GTGCGCGCCATCTCCGCGACGGCGCATCGTCACGGCGCATTGTCCATCGTGGACAACACGTTCGCGACCCCGTACCTGCA
GCAGCCGCTTTCCCTCGGCGCGGATGTGGTGATTCATTCCGCCACCAAGTACTTGGCCGGCCACTCCGACGTCAATGCCG
GTCTTGTGGTCGTATCCAGTGAGGATCTGGCCAATCGCGTGTACTTCGCGCAGAATCGTCTCGGTGGGGTCCTGGCGCCC
GCCGAATGTGATTCGGTGCGTCGCGGCATACAGACGTTGGCCTTGCGTATGGATCGTCAGCAGGAAAACGCGAACGCCCT
CGCCCGGTATCTGCTCGCTCACCCATTGGTCAAATCCGTTCACTATCCAGGATTGCCCGGTGCCGGCGATCAGCGGCTCG
CAGCCAAGGGGTTGAAGGGCGCCGGCGGCGTGCTGAGCTTCGAAGTGGTGCCTGGCGTGGACCCTGCGGATGTGCTCAAC
AACCTGCACATCTTCCGATTGGCTGTGTCCCTTGGTGCCGTGGAATCGCTTGCGGAACTGCCTTGCCGCATGACGCATTT
CGAACTGCCCCGGGAGGAGCGTCTGAAGGTCGGCATCACCGATGAGCTGGTGCGTCTCGCCGTCGGCATCGAGGATGCGA
ACGATCTGATCGAAGACCTCGGACAGGCTTTCGATATCGCCTATGCCCGATACAGGGAACGCCACATCGACTCCGATGTA
CTTGGCGCATTGACTCCGAAGGTGTTCGCTTGA

Protein sequence :
MTRFNTQLVHGLPVDDNDTGAVNPPIYNSTTYAFERVDAMPRYDYARSGNPTRDFLERQIAQLEQGKRGFAFASGLAAIH
AVLSTFKPGDRIVVGDNIYGGTYSQLNEFFTRWGLVVESVNTRDDAALESAVRGDRANGVAPARAVYFETLTNPLLKVND
VRAISATAHRHGALSIVDNTFATPYLQQPLSLGADVVIHSATKYLAGHSDVNAGLVVVSSEDLANRVYFAQNRLGGVLAP
AECDSVRRGIQTLALRMDRQQENANALARYLLAHPLVKSVHYPGLPGAGDQRLAAKGLKGAGGVLSFEVVPGVDPADVLN
NLHIFRLAVSLGAVESLAELPCRMTHFELPREERLKVGITDELVRLAVGIEDANDLIEDLGQAFDIAYARYRERHIDSDV
LGALTPKVFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-72 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-73 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Blon_0748 YP_002322230.1 cystathionine gamma-synthase BAC0207 Protein 2e-59 41