Gene Information

Name : guaA (Blon_1723)
Accession : YP_002323177.1
Strain : Bifidobacterium longum JCM 1222
Genome accession: NC_011593
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1889657 - 1891219 bp
Length : 1563 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCAAACGGTCCTGTGCTTGTCGTCGACTTCGGCGCCCAGTACGCCCAGCTCATCGCCCGCCGCGTGCGCGAAGCAGG
CGTGTACTCCGAGCTGGTCCCTCATTCCATGCCGGTTGACGAGATCCTGGCCAAGGATCCGAAGGCGATTATTCTGTCCG
GCGGCCCGGCCTCTGTGTTCGAGCCCGGCGCGCCGACCATAGATACTAAGGTATTCGAATCCGGTGTTCCTGTGCTTGGT
ATCTGTTACGGCTTCCAGGTCATGGCCTATGAGCTCGGCGGCAAGGTGGATAAGGCCGCTCTCGGCGAATACGGCAAGAC
CTCAGCCACCATCGATGACGCCGACGGCATCCTCGCCGACTCCCCCGCCGAGCAGACCACGTGGATGAGCCACGGTGTGG
CGGTCGAACAGGCCCCGGCCGGCTTCGAAGTGCTGGCCCACACCGAAGGCGCGCCCGTGGCCGCCATGGCGGACGAATCC
CGCAAGCTCTATGGTGTGCAGTGGCACCCGGAAGTCAAGCACTCCCCGCTTGGCCAGAAGCTTATCGAAAACTTCCTGCA
CCGTTGCGCCGCGCTGCCCAACGACTGGGATGCCTCCTCGATTATCGAGGATCAAGTCAAGAAGATCCGCGAGAAGGTCG
GCGACGCCGAGGTGATCTGCGGCCTGTCCGGCGGCGTGGACTCCGCCGTGGCCGCCGCTCTGGTGCACAAGGCCATCGGC
GACCAGCTCACCTGCGTGTTCGTGGACCACGGCCTGCTGCGTAAGGGCGAGGTCGAGCAGGTCAAGCACGACTTCGTTGC
CGCCACCGGCATCAAGCTCATCACCGTGGACGCGGCCGACGACTTCCTTGAGGCCCTGAAGGGAGTCTCCGAGCCGGAGC
GCAAGCGCAAGATCATCGGTGAGAAGTTCATCCGCACGTTCGAGAAGGCCCAGCGCCAAGTGCTTGAAGAGGCCGGCGCG
CGCGGCAAGGAAGTCAAGTTCCTCGTGCAGGGCACCCTCTACCCCGACGTCGTCGAATCCGGCGGCGGCGACGGCGCGGC
CAACATCAAGTCCCACCACAACGTCGGCGGCCTGCCCAAGGACATCAAGTTCCAGCTCATCGAACCGCTGCGCACTCTGT
TCAAGGATGAGGTGCGCGCCATCGGCACCGAGCTCGGTCTGCCCGACGAAATCGTCTGGCGTCAGCCTTTCCCGGGCCCG
GGTCTGGGCATCCGCATCATCGGCGAGATCACCAAGGAGCGCCTCGACCTGCTGCGCGAGGCCGACGCCATCGCCCGCGA
GGAGCTCTCCAAGGCCGGTCTCGACCGCGACATCTGGCAGTGCCCGGTCGTGCTGCTCGCCGACGTTCACTCGGTGGGCG
TCCAGGGTGACGAGCGCACCTACGGCTCCCCCATCGTGCTGCGCCCGGTGAGCTCGGAAGACGCCATGACCGCCGACTGG
TCTCGCGTGCCCTACGACGTGCTCGCCACGATCTCCACGCGCATCACCAACGAGTGCCGCCAGATCAACCGCGTCGTCCT
CGATTGCACGAGCAAGCCGCCGGCCACAATTGAATGGGAGTAA

Protein sequence :
MANGPVLVVDFGAQYAQLIARRVREAGVYSELVPHSMPVDEILAKDPKAIILSGGPASVFEPGAPTIDTKVFESGVPVLG
ICYGFQVMAYELGGKVDKAALGEYGKTSATIDDADGILADSPAEQTTWMSHGVAVEQAPAGFEVLAHTEGAPVAAMADES
RKLYGVQWHPEVKHSPLGQKLIENFLHRCAALPNDWDASSIIEDQVKKIREKVGDAEVICGLSGGVDSAVAAALVHKAIG
DQLTCVFVDHGLLRKGEVEQVKHDFVAATGIKLITVDAADDFLEALKGVSEPERKRKIIGEKFIRTFEKAQRQVLEEAGA
RGKEVKFLVQGTLYPDVVESGGGDGAANIKSHHNVGGLPKDIKFQLIEPLRTLFKDEVRAIGTELGLPDEIVWRQPFPGP
GLGIRIIGEITKERLDLLREADAIAREELSKAGLDRDIWQCPVVLLADVHSVGVQGDERTYGSPIVLRPVSSEDAMTADW
SRVPYDVLATISTRITNECRQINRVVLDCTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-170 68
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-141 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-141 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-141 54